Recovery from Receptive Amusia Suggests Functional Reorganization of Music- Processing Networks
Abstract
Abstract: A follow-up study was performed in patients suffering from receptive amusia due to unilateral cerebrovascular cortical lesions. Perceptual musical functions had initially been assessed within the 5th and 10th day post-lesion and were re-evaluated 6-12 months after brain-damage. The standardized test battery covered local and global strategies of music perception in discrimination tasks. Retest sessions showed an overall improvement of music perception, reaching a significant group effect over all tasks. Marked improvement up to normal range was seen in four patients. These findings demonstrate the possibility of recovery from receptive amusia that can be assumed to be based on cerebral plasticity changes. Extremely mixed patterns of recovery support the hypothesis of a highly individual formation of music processing networks.
Zusammenfassung: Bei Patienten mit rezeptiver Amusie infolge einseitiger cortikaler cerebrovaskulärer Läsionen wurden Follow-up Untersuchungen durchgeführt. Die rezeptiven musikalischen Fertigkeiten der Patienten wurden erstmalig zwischen dem fünften und zehnten Tag postläsional getestet und nach weiteren sechs bis zwölf Monaten reevaluiert. Die standardisierte Testbatterie erfasste lokale und globale musikalische Verarbeitungsweisen in Form von Diskriminationsaufgaben. In den Wiederholungsmessungen zeigte sich eine allgemeine Verbesserung der Musikwahrnehmung mit signifikantem Gruppeneffekt über alle Aufgaben. Vier Patienten verbesserten sich erheblich bis in den Normbereich. Die Ergebnisse demonstrieren die Möglichkeit einer Regeneration von rezeptiver Amusie und lassen als Ursache cerebrale plastische Veränderungen vermuten. Die extrem unterschiedlichen Regenerationsmuster der Patienten unterstützen die Annahme hochgradig individuell formierter musikverarbeitender cortikaler Netzwerke.
LHD = left-hemisphere damage; RHD = right-hemisphere damage; MIDI = Musical Instrument Digital Interface; ANOVA = analysis of variance
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