Abstract
Zusammenfassung: Ein Patient (S.W.) und eine Patientin (M.E.) mit intracerebraler Blutung in der rechten Hemisphäre und hemispatialem Neglect führten Linienhalbierung im nahen und fernen Raum mit der rechten und linken Hand durch. S.W. zeigte im Greifraum Verbesserungen bei Einsatz der kontraläsionalen Hand. Dieser Effekt war fehlend bis gegenläufig im extrapersonalen Raum. M.E. zeigte nur extrapersonal Verbesserungen unter kontraläsionalem Handeinsatz. Die Ergebnisse konnten mehrfach repliziert werden. Bei beiden Patienten war der Neglect extrapersonal stärker ausgeprägt als peripersonal. Die Dissoziation der Wirkung kontraläsionaler Aktivität auf den Neglect im peripersonalen und extrapersonalen Raum wurde als Hinweis auf differentielle Aufmerksamkeitssysteme interpretiert. Die Ergebnisse stehen im Einklang mit Tiermodellen und PET-Studien an gesunden Personen.
Abstract: A male (S.W.) and a female patient (M.E.) with right hemisphere lesions and hemispatial neglect conducted line bisection in near and far space using alternately right and left hand. S.W. showed improvement using his contralesional limb in near space. This effect was missing or opposite in far space. M.E. showed improvement only in far space using her contralesional limb. Results could be replicated several times. Neglect in extrapersonal space was more pronounced than in peripersonal space by both patients. The dissociational effect of contralesional activity on neglect in peri- and extrapersonal space was interpreted as a support for the hypotheses of different attentional systems for these spacial functions. Results are compatible with animal models and PET-Studies of healthy subjects.
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