Abstract
Abstract.Background: The number of older adults with alcohol use disorder (AUD) is expected to rise. Adapted treatments for this group are lacking and information on AUD features in treatment seeking older adults is scarce. The international multicenter randomized-controlled clinical trial “ELDERLY-Study” with few exclusion criteria was conducted to investigate two outpatient AUD-treatments for adults aged 60+ with DSM-5 AUD. Aims: To add to 1) basic methodological information on the ELDERLY-Study by providing information on AUD features in ELDERLY-participants taking into account country and gender, and 2) knowledge on AUD features in older adults seeking outpatient treatment. Methods: baseline data from the German and Danish ELDERLY-sites (n=544) were used. AUD diagnoses were obtained with the Mini International Neuropsychiatric Interview, alcohol use information with Form 90. Results: Lost control, desired control, mental/physical problem, and craving were the most prevalent (> 70 %) AUD-symptoms. 54.9 % reported severe DSM-5 AUD (moderate: 28.2 %, mild: 16.9 %). Mean daily alcohol use was 6.3 drinks at 12 grams ethanol each. 93.9 % reported binging. More intense alcohol use was associated with greater AUD-severity and male gender. Country effects showed for alcohol use and AUD-severity. Conclusion: European ELDERLY-participants presented typical dependence symptoms, a wide range of severity, and intense alcohol use. This may underline the clinical significance of AUD in treatment-seeking seniors.
Zusammenfassung.Hintergrund: Für die Zukunft wird ein Anstieg des Anteils älterer Menschen mit Alkoholkonsumstörung (AKS) in westlichen Ländern erwartet. An die Bedürfnisse dieser Gruppe angepasste Interventionen fehlen bislang. Über die klinischen Merkmale behandlungssuchender Senioren mit AKS ist wenig bekannt. In der internationalen, multizentrischen, randomisiert-kontrollierten Therapiestudie „ELDERLY-Study” mit wenigen Ausschlusskriterien wurden zwei kurze ambulante Interventionen für Erwachsene im Alter 60+ mit AKS nach DSM-5 untersucht. Ziele: 1) Die Informationen zur Methodik der ELDERLY-Studie um Informationen zu den klinischen Merkmalen der AKS in der Stichprobe und in Subgruppen nach Geschlecht und Land zu ergänzen und 2) Informationen über AKS-Merkmale bei behandlungssuchenden älteren Menschen bereitzustellen . Methoden: Verwendet wurden Baselinedaten der dänischen und deutschen Studienteilnehmer (n=544). DSM-5 AKS-Diagnosen wurden mit dem Mini International Neuropsychiatric Interview, Alkoholkonsum mit der Form 90 erhoben. Ergebnisse: Kontrollverlust, erfolglose Kontrollversuche, Konsum trotz körperlicher und/oder seelischer Konsequenzen und Craving waren die häufigsten AKS-Symptome (> 70 %). 54.9 % berichteten eine schwergradige AKS, (mittelgradig: 28.2 %, leichtgradig: 16.9 %). Die durchschnittliche tägliche Trinkmenge betrug 6.3 Standardgetränke á 12 Gramm Ethanol. 93.9 % berichteten Rauschtrinken. Ein stärker ausgeprägtes Konsumverhalten war mit höherem AKS-Schweregrad und männlichem Geschlecht assoziiert. Unterschiede zwischen den Ländern zeigten sich für Konsummuster und Schweregrad. Schlussfolgerungen: ELDERLY-Teilnehmer aus zwei europäischen Ländern zeigten typische Abhängigkeitssymptome, intensive Konsummuster und alle AKS-Schweregrade. Diese Befunde unterstreichen die klinische Bedeutsamkeit von Symptomberichten bei behandlungssuchenden Senioren mit AKS.
Literature
American Psychiatric Association . (2013). Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition). Arlington, VA: American Psychiatric Publishing.2015). Outpatient treatment of alcohol use disorders among subjects 60+years: design of a randomized clinical trial conducted in three countries (Elderly Study). Bmc Psychiatry, 15.
, (2017). Prevalence of mental disorders in elderly people: the European MentDis_ICF65+study. British Journal of Psychiatry, 210(2), 125–131.
, (2004). Combined Behavioral Intervention Manual. A clinical research guide for therapists treating people with alcohol abuse and dependence (W. R. Miller Ed. Vol. 1): National Institute on Alcohol Abuse and Alcoholism, U. S. Department of Health and Human Services, National Institutes of Health.
, (2016). Drinking Over the Lifespan: Focus on Older Adults. Alcohol Research-Current Reviews, 38(1), 115–120.
(2007). Detection and management of alcohol use disorders in German primary care influenced by non-clinical factors. Alcohol and Alcoholism, 42(4), 308–316.
(2015). Recent advances in treatment for older people with substance use problems: An updated systematic and narrative review. European Geriatric Medicine, 6(6), 580–586.
(2009). The Epidemiology of At-Risk and Binge Drinking Among Middle-Aged and Elderly Community Adults: National Survey on Drug Use and Health. American Journal of Psychiatry, 166(10), 1162–1169.
(2011). The Epidemiology of Alcohol Use Disorders and Subthreshold Dependence in a Middle-Aged and Elderly Community Sample. American Journal of Geriatric Psychiatry, 19(8), 685–694.
(2000). Older adult treatment outcome following elder-specific inpatient alcoholism treatment. Journal of Substance Abuse Treatment, 19(1), 67–75.
(2007). One drink, one drunk – Controlled drinking by alcoholics? 3-year-outcome after intensive outpatient treatment. Psychotherapie Psychosomatik Medizinische Psychologie, 57(1), 32–38.
(2012). Alcohol use disorders in the elderly: A brief overview from epidemiology to treatment options. Experimental Gerontology, 47(6), 411–416.
(2014). Treatment use, perceived need, and barriers to seeking treatment for substance abuse and mental health problems among older adults compared to younger adults. Drug and Alcohol Dependence, 145, 113–120.
(2011). Binge Drinking and Axis I Psychiatric Disorders in Community-Dwelling Middle-Aged and Older Adults: Results From the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). Journal of Clinical Psychiatry, 72(5), 640–647.
(2013). Older adult problem drinkers: Who presents for alcohol treatment? Aging & Mental Health, 17(1), 24–32.
(2012). Alcohol limits in older people. Addiction, 107(9), 1541–1543.
(2011). Sex Differences in Impulsivity: A Meta-Analysis. Psychological Bulletin, 137(1), 97–130.
(2017). Assertive Community Treatment For People With Alcohol Dependence: A Pilot Randomized Controlled Trial. Alcohol and Alcoholism, 52(2), 234–241.
, (1976). Alcohol dependence: provisional description of a clinical syndrome. British Medical Journal, 1, 1058–1061.
(2017). How Do Older Adults with Very-Late-Onset Alcohol Use Disorder Define Alcohol Problems? Results from an Interpretative Phenomenological Study. Alcoholism Treatment Quarterly, 35(2), 151–164.
(2013). Increases in alcohol consumption in women and elderly groups: evidence from an epidemiological study. Bmc Public Health, 13.
(German Federal Center for Health Education . (2017). http://www.kenn-dein-limit.info/alkohol-in-zahlen.html.2015). Epidemiology of DSM-5 Alcohol Use Disorder Results From the National Epidemiologic Survey on Alcohol and Related Conditions III. Jama Psychiatry, 72(8), 757–766.
, (2017). Demographic trends of binge alcohol use and alcohol use disorders among older adults in the United States, 2005–2014. Drug and Alcohol Dependence, 170, 198–207.
(2009). Epidemiologie des Alkoholkonsums bei älteren Menschen in Privathaushalten: Ergebnisse des telefonischen Gesundheitssurvey 2007.
(Epidemiology of alcohol consumption among elderly people living in private households: Results from the 2007 Telephone Health Survey . SUCHT, 55(5), 281–291.2013). Alcohol consumption, at-risk and heavy episodic drinking with consideration of injuries and alcohol-specific medical advice. Results of the German Health Interview and Examination Survey for Adults (DEGS1). Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz, 56(5–6), 809–813.
(2009). Research electronic data capture (REDCap) – A metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform, 377–381.
(2006). Age of Alcohol-Dependence Onset: Associations With Severity of Dependence and Seeking Treatment. Pediatrics, 118(3), 755–763.
(2015). Twelve-months prevalence of mental disorders in the German Health Interview and Examination Survey for Adults – Mental Health Module (DEGS1-MH): a methodological addendum and correction. International Journal of Methods in Psychiatric Research, 24(4), 305–313.
, (2001). The reliability of self-reported age of onset of tobacco, alcohol and illicit drug use. Addiction, 96, 1187–1198.
(2010). Stigma and Treatment for Alcohol Disorders in the United States. American Journal of Epidemiology, 172(12), 1364–1372.
(2013). Functioning of Alcohol Use Disorders Criteria Among Middle-Aged and Older Adults: Implications for DSM-5. Substance Use & Misuse, 48(4), 309–322.
(2017). Alkoholkonsum bei Erwachsenen in Deutschland: Riskante Trinkmengen. Journal of Health Monitoring, 2(2), 66–73.
(1997). The MINI International Neuropsychiatric Interview (M. I. N. I.) A Short Diagnostic Structured Interview: Reliability and Validity According to the CIDI. European Psychiatry, 12, 224–231.
(2011). Alcohol, Tobacco, and Nonmedical Drug Use Disorders in US Adults Aged 65 Years and Older: Data From the 2001–2002 National Epidemiologic Survey of Alcohol and Related Conditions. American Journal of Geriatric Psychiatry, 19(3), 292–299.
(2016). Applied Ordinal Logistic Regression Using Stata. Thousand Oaks, CA: Sage Publications
(2014). Self-reported utilization of mental health services in the adult German population – evidence for unmet needs? Results of the DEGS1-MentalHealthModule (DEGS1-MH). International Journal of Methods in Psychiatric Research, 23(3), 289–303.
(2016). The importance of age groups in estimates of alcohol-attributable mortality: impact on trends in Switzerland between 1997 and 2011. Addiction, 111(2), 255–262.
(1994). Measurement of drinking behavior using the Form-90 family of instruments. Journal of Studies on Alcohol, 112–118.
(2012). Interpreting and Visualizing Regression Models Using Stata. Retrieved from College Station, TX:
(National Institutes of Health . (2016). ClinicalTrials.gov. Retrieved 08.11.2016NIAAA . (2016). http://www.niaaa.nih.gov/alcohol-health/special-populations-co-occurring-disorders/older-adults.2010). Adolescence as a critical window for developing an alcohol use disorder: current findings in neuroscience. Current Opinion in Psychiatry, 23(3), 227–232.
(2015). Prevalence of Alcohol Consumption and Pattern of Use among the Elderly in the WHO European Region. European Addiction Research, 21(2), 88–96.
(2002). Alcoholism treatment adherence – Older age predicts better adherence and drinking outcomes. American Journal of Geriatric Psychiatry, 10(6), 740–747.
(2013). Substance Use and Substance Use Disorders in Germany in 2012. SUCHT, 59(6), 321–331.
(2017). Stability and change in reported age of onset of depression, back pain, and smoking over 29 years in a prospective cohort study. Journal of Psychiatric Research, 88, 105–112.
(2016). Kurzbericht Epidemiologischer Suchtsurvey 2015 (Tabellenband: Alkoholkonsum, episodisches Rauschtrinken und Hinweise auf klinisch relevanten Alkoholkonsum nach Geschlecht und Alter im Jahr 2015). München: IFT Institut für Therapieforschung.
(2017). Substanzkonsum und Hinweise auf klinisch relevanten Konsum in Bayern, Hamburg, Hessen, Nordrhein-Westfalen, Sachsen und Thüringen. Ergebnisse des Epidemiologischen Suchtsurvey 2015. München: IFT Institut für Therapieforschung.
(2015). Prevalence of psychiatric disorders in US older adults: findings from a nationally representative survey. World Psychiatry, 14(1), 74–81.
(1986). Model robust confidence intervals using maximum likelihood estimators. Statistical Review, 54, 221–226.
(2004). Five-year alcohol and drug treatment outcomes of older adults versus middle-aged and younger adults in a managed care program. Addiction, 99(10), 1286–1297.
(2017). Changes in profile of patients seeking alcohol treatment and treatment outcomes following policy changes. Journal of Public Health., DOI 10.1007/s10389-017-0841-0.
(1984). Alcohol Dependence Scale: Users Guide. Toronto, Canada: Addiction Research Foundation.
(2016). The RESCueH Programme: Testing New Non-Pharmacologic Interventions for Alcohol Use Disorders: Rationale and Methods. European Addiction Research, 22(6), 306–317.
. (StataCorp .(Ed.) (2017). Stata Statistical Software: Release 14.2 College Station, TX: StataCorp LP.2009). At-risk alcohol drinking in primary care patients aged 75 years and older. International Journal of Geriatric Psychiatry, 24(12), 1376–1385.
. (2011). Multiple imputation using chained equations: Issues and guidance for practice. Statistics in Medicine, 30(4), 377–399.
(2008). Anticipating problem alcohol use developmentally from childhood into middle adulthood: what have we learned? Addiction, 103(Supplement 1), 100–108.
(