Defizite in den Exekutivfunktionen von Kindern mit ADHS
Zur klinischen Validität des ADHS-Diagnostikums für Kinder und Jugendliche (ADHS-KJ)
Abstract
Zusammenfassung. Das Erhebungsverfahren ADHS-KJ beinhaltet eine differenzierte neuropsychologische Erfassung der exekutiven Funktionen sowie eine standardisierte Verhaltensbeobachtung des hyperaktiven Verhaltens von Kindern und Jugendlichen im Alter von 6;0 bis 12;11 Jahren. Die Aussagekraft des neuropsychologischen Moduls des ADHS-KJ wurde anhand einer Gruppe von Kindern mit einer ADHS-Diagnose (n = 58) und einer parallelisierten Kontrollgruppe untersucht (n = 58); es wurde überprüft, inwieweit das Alter und die medikamentöse Behandlung der Kinder die Ergebnisse beeinflussten. Zusätzlich wurden die neuropsychologischen Ergebnisse mit Befunden einer standardisierten Verhaltensbeobachtung in Zusammenhang gesetzt. Es wurde belegt, dass das Erhebungsverfahren ADHS-KJ zwischen Kindern mit und ohne eine ADHS auf der Basis der Komponenten der exekutiven Funktionen und des darauf bezogenen Gesamttestwertes des ADHS-KJ sowie der Beobachtung des hyperkinetischen Verhaltens differenzieren konnte. Die Unterschiede zwischen der ADHS- und Kontrollgruppe wurden durch kleine (d = .36) bis große (d = .95) Effektstärken gekennzeichnet. Das Erhebungsverfahren ADHS-KJ differenzierte deutlich zwischen jüngeren und älteren Kindern mit ADHS (d ≥ 1.00). Das Erhebungsverfahren ADHS-KJ kann als multimodales und multimethodales Vorgehen für die Diagnostik einer ADHS empfohlen werden, wobei die Auffälligkeiten in den Exekutivfunktionen besonders kennzeichnend für Kinder der Altersgruppe von sechs bis acht Jahren sind.
Abstract. The diagnosis of attention deficit hyperactivity disorder (ADHD) poses a challenge to therapists because ADHD has been declared a behavioral disorder for a long time. Therefore, the diagnosis is based on observable behavior, which is subject to various deviations. According to the current understanding of the disorder, the self-regulation of children with ADHD is disturbed, which is associated with deficits in executive functions. The aim of this study was to validate a diagnostic instrument for ADHD (ADHS-KJ; Petermann & Petermann, 2019) and to check whether the neuropsychological test and the Behavioural Observation Scale of Hyperactivity differ between children with ADHD (n = 58) and a parallel control group (n = 58). In addition, we controlled for age effects comparing the scores of children in the neuropsychological test and the Behavioral Observation Scale in two age groups (n = 14: 6.0 – 7.99 and n = 13: 10.0 – 12.99). The influence of psychopharmacological medication on these scores was also examined by comparing children with ADHD who received some medication (n = 31), children with ADHD without medication (n = 27), and children without ADHD (n = 31). Multivariate variance analyses were performed to investigate group differences using effect sizes (Cohen’s d) to evaluate the magnitude of differences in the executive functions between the clinical and the control group. The results of the present study showed significant differences between children with and without clinical ADHD in the area of Flexible Attention Control Deficits: Divided Attention (Subtest 1; d = .40), Deficits in Action Planning to Achieve a Goal Without Errors (Subtest 2; d = .57), Deficits in Inhibition of External Stimuli for Attention Control (Subtest 3; d = .36), Deficits in Inhibition of Internal Impulses to the Reaction Stop (Subtest 4; d = .39), overall Deficits of the Executive Functions (DEF; d = .63), and the Behavioural Observation Scale of Hyperactivity (VBH; d = .95). These effect sizes are to be interpreted as small to large. Age differences were detected in all subtests, with the exception of the subtest Deficits in Inhibition of Internal Impulses for Reaction Stop. Differences were also found in the overall score of Deficits of the Executive Functions (DEF) and the Behavioral Observation Scale of Hyperactivity (VBH) with large effect sizes (d ≥ 1.00). Influences related to medications of children with an ADHD diagnosis were only found to be significant in the subtest Deficits in Inhibition of External Stimuli for Attention Control (d =.70). The study was able to detect significant differences of the ADHD group in comparison with the control group as well as difference in the age group comparison. These findings support the hypothesis that the diagnostic instrument ADHS-KJ is suitable for use in diagnostics of children without medication. The multimodal and multimethod diagnostic instrument ADHS-KJ is recommended in the diagnostics of ADHD in order to support the observable behavior of the affected child with psychometrically secured data and to identify the exact source of possible impairments or deviations. The information provided by the ADHS-KJ makes a significant contribution to diagnostic clarification and individual therapy planning.
Literatur
1993). Teachers’ ratings of disruptive behaviors: The influence of halo effects. Journal of Abnormal Child Psychology, 21, 519 – 533.
(2013). Diagnostic and statistical manual of mental disorders (DSM-5). Washington, DC: American Psychiatric Association.
(2017). Leitlinienreport der interdisziplinären evidenz- und konsensbasierten (S3) Leitlinie „Aufmderksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) im Kindes-, Jugend- und Erwachsenenalter“. Verfügbar unter https://www.awmf.org/uploads/tx_szleitlinien/028-045l_S3_ADHS_2018-06.pdf
(2015). Cognitive computer training in children with attention deficit hyperactivity disorder (ADHD) versus no intervention: Study protocol for a randomized controlled trial. Trials, 16, 480 – 493.
(2018). Parent-based diagnosis of ADHD is a accurate as a teacher-based diagnosis of ADHD. Postgraduate Medicine, 129, 375 – 381.
(2008). Stability of executive function deficits in girls with ADHD: A prospective longitudinal followup study into adolescence. Developmental Neuropsychology, 33, 44 – 61.
(2018). The association between executive functioning and psychopathology: General or specific? Psychological Medicine, 48, 1787 – 1794.
(2018). ADHS bei Kindern und Erwachsenen – eine neue Sichtweise. Bern: Hogrefe.
(2012). Is ADHD diagnosed in accord with diagnostic criteria? Overdiagnosis and influence of client gender on diagnosis. Journal of Consulting and Clinical Psychology, 80, 128 – 138.
(1988). Statistical power analysis for the behavioral sciences (2nd ed.). Hillsdale, NJ: Erlbaum.
(2005). Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS): Wie valide sind Subtypen? Kindheit und Entwicklung, 14, 244 – 254.
(2015). Improving executive functioning in children with ADHD: Training multiple executive functions within the context of a computer game. A randomized double-blind placebo controlled trail. PLoS One, 10, 1 – 30.
(2004). How specific are executive functioning deficits in attention deficit hyperactivity disorder and autism? Journal of Child Psychology and Psychiatry, 45, 836 – 854.
(2005). ADHD subtypes: Do they differ in their executive functioning profile? Archives of Clinical Neuropsychology, 20, 457 – 477.
(2009). Exekutive Funktionen bei Jungen mit Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung im Kindesalter. Kindheit und Entwicklung, 18, 144 – 152.
(2018). Cross-informant disagreement on behavioral symptoms in adolescent Attention-Deficit/Hyperactivity Disorder and its impact on treatment effects. European Journal of Psychological Assessment, 34, 79 – 86.
(2010). The diagnostic utility of executive function assessments in the identification of ADHD in children. Child and Adolescent Mental Health, 15, 37 – 43.
(2018). ADHD and the QbTest: Diagnostic validity of QbTest. Journal of Attention Disorders, 22, 1074 – 1080.
(2004). Gender differences in the effects of oppositional behavior on teacher ratings of ADHD symptoms. Journal of Abnormal Child Psychology, 32, 215 – 224.
(2007). Aufmerksamkeitstörungen bei Kindern. Langzeiteffekte des neuropsychologischen Gruppenprogrammes ATTENTIONER. Kindheit und Entwicklung, 16, 40 – 49.
(2013). Training für Kinder mit Aufmerksamkeitsstörungen. Das neuropsychologische Gruppenprogramm ATTENTIONER (3., veränd. Aufl.). Göttingen: Hogrefe.
(2019). Zum Zusammenhang von Arbeitsgedächtnisleistungen und ausgewählten Exekutivfunktionen bei Kindern mit ADHS. Ein Beitrag zur Kriteriumsvalidität des ADHS-KJ. Kindheit und Entwicklung, 28, 114 – 122.
(2012). Neurocognitive training for children with and without AD/HD. Attention Deficit Hyperactivity Disorder, 4, 11 – 23.
(2018). Executive function heterogeneity in pediatric ADHD. Journal of Abnormal Child Psychology. Advance online publication https://doi.org/10.1007/s10802-018-0438-2
(2012). Can task-switching training enhance executive control functioning in children with attention deficit/-hyperactivity disorder? Frontiers in Human Neuroscience, 5, 1 – 9.
(2018). Equivalence of mother and father ratings of ADHD in children. Child Neuropsychology, 24, 166 – 183.
(2018). A review of the clinical utility of systematic behavioral observations in Attention Deficit Hyperactivity Disorder (ADHD). Child Psychiatry & Human Development, 49, 572 – 606.
(2000). The unity and diversity of executive functions and their contributions to complex “Frontal Lobe“ tasks: A latent variable analysis. Cognitive Psychology, 41, 49 – 100.
(2018). Gender differences in the relationship between changes in ADHD symptoms, executive functions, and self- and parent-report depression symptoms in boys and girls with ADHD: A 2-year follow-up study. Journal of Attention Disorders, 22, 446 – 459.
(2018). Intelligenzdiagnostik bei Kindern und Jugendlichen mit ADHS. Kindheit und Entwicklung, 27, 165 – 174.
(2019). ADHS-Diagnostikum für Kinder und Jugendliche (ADHS-KJ). Bern: Hogrefe.
(2009). Neuropsychologische Diagnostik bei Kindern mit ADHS. Kindheit und Entwicklung, 18, 83 – 94.
(2015). Effect of training focused on executive functions (attention, inhibition, and working memory) in preschoolers exhibiting ADHD symptoms. Frontiers in Psychology, 6, 1 – 9.
(2018). Zur Bedeutung auffälliger Exekutivfunktionen in der Diagnostik einer Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung. Zeitschrift für Psychiatrie, Psychologie und Psychotherapie, 66, 207 – 217.
(2006). Komorbidität der Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) im Erwachsenenalter: Perspektiven für die Diagnostik mit dem Screeningverfahren BAS-E. Zeitschrift für Psychiatrie, Psychologie und Psychotherapie, 54, 123 – 132.
(2009). Training and transfer effects of executive functions in preschool children. Developmental Science, 12, 106 – 113.
(2011). Assessments for attention-deficit hyperactivity disorder: Use of objective measurements. The Psychiatrist, 35, 380 – 383.
(2009). Heterogeneity in ADHD: Neuropsychological pathways, comorbidity and symptoms domains. Journal of Abnormal Child Psychology, 37, 551 – 561.
(2011). Neuropsychological outcomes across the day in children with attention-deficit/hyperactivity disorder treated with Atomoxetine: Results from a placebo-controlled study using a computer-based continous performance test combined with an infra-red motion-tracking device. Journal of Child an Adolescent Psychopharmacology, 21, 433 – 444.
(2009). International statistical classification of diseases and related health problems (ICD-10). Genf: WHO.
(2018). ICD-11 for mortality and morbidity statistics. Retrieved from https://icd.who.int/browse11/l-m/
(2005). Validity of the executive function theory of Attention-Deficit/Hyperactivity disorder: A meta-analytic review. Biological Psychiatry, 57, 1336 – 1346.
(2012). Comparative study of OROS-MPH and atomoxetine on executive function improvement in ADHD: A randomized controlled trial. International Journal of Neuropsychopharmacology, 15, 15 – 26.
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