Abstract. In the development of new psychiatric drugs and the exploration of their efficacy, behavioral testing in mice has always shown to be an inevitable procedure. By studying the behavior of mice, diverse pathophysiological processes ...

Abstract. Inflammational-immunological processes within the pathophysiology of schizophrenia seem to play an important role. Early signals of neurobiological changes in the embryonal phase of brain in later patients with schizophrenia ...

Abstract. Phosphatidylinositol-3-kinase (PI3K) signaling influences susceptibility to virus infections, anoxia, obstetric complications, and cancer; which are changed in patients with schizophrenia and their first degree relatives. ...

Abstract. The present study explored the impact of Akt1 and Akt3 on behavior. Akt1 (akt1^-/-) and Akt3 (akt3^-/-) knockout mice were compared to wild type (wt) mice. The akt1^-/- mice, akt3^-/- mice, and wt mice were ...

Abstract. The impact of the environment early in life on long-term outcomes is well known. Stressful experiences during pre- and postnatal development can modulate the genetic programming of specific brain circuits underlying emotional and ...

Abstract. Animal-assisted therapy (AAT) has been shown to be effective in recent meta-analyses with an improvement of mental health, quality of life, and a decrease in the sense of isolation. Reduction of depressive symptoms in human ...