Original Communication
Lipid Peroxidation in Nicotinamide-Deficient and Nicotinamide-Supplemented Rats
Published Online:March 14, 2013https://doi.org/10.1024/0300-9831.70.6.321
Abstract
Supplementation or deficiency of nicotinamide in rats may interfere with the oxidative balance, with excess leading to greater lipid peroxidation, measured by TBARS, and deficiency causing a greater consumption of antioxidants such as vitamin E and glutathione. Urinary N-methylnicotinamide excretion was much more marked in the supplemented group, whereas the difference between deficient and control animals was non-significant.
