Abstract
Abstract: Parkinson’s disease (PD) leads to cognitive impairment. Widely used methods to assess cognition are the Clock Drawing Test (CDT) and the Mini-Mental State Examination (MMSE). Another option is the Vienna Visuo-Constructional Test 3.0 Screening (VVT-3.0). We studied the neuropsychological and demographic data of 45 healthy controls (HC) and 64 individuals diagnosed with PD (total N = 109) and compared the validity of each test by using receiver-operator characteristic (ROC) curves and logistic regression analyses. The ROC analyses of PD yielded areas under the curve (AUC) of 0.68 using VVT-3.0, 0.74 using MMSE, and 0.72 using CDT as predictors, respectively. The VVT-3.0 shows comparable validity to the more established measurement tools and MMSE und CDT and is easy to administer in a clinical setting.
Zusammenfassung: Die Parkinson-Krankheit führt zu einer kognitiven Beeinträchtigung. Weit verbreitete Methoden zur Erfassung der Kognition sind der Uhrentest und die Mini-Mental State Examination, eine weitere Option ist das Vienna Visuo-Constructional Test 3.0 Screening. Neuropsychologische und demographische Daten von 45 gesunden Kontrollpersonen und 64 Parkinsonpatienten (N = 109) wurden untersucht. Die Validität jedes Tests wurde anhand von Receiver Operator Characteristic (ROC)-Kurven und logistischen Regressionsanalysen verglichen. ROC-Analysen ergaben eine AUC von 0.68 für den VVT-3.0 von 0.74 für den MMSE und 0.72 für den CDT als Prädiktor. Der VVT-3.0 zeigt eine vergleichbare Validität wie die etablierten Messinstrumente MMSE und CDT und ist im klinischen Setting einfach anzuwenden.
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