Skip to main content
Published Online:https://doi.org/10.1026/1616-3443/a000446

Zusammenfassung.Hintergrund: Neben störungsspezifischen Behandlungskonzepten werden in den letzten Jahren vermehrt transdiagnostische Behandlungsmanuale in der expositionsbasierten Behandlung von Ängsten und komorbiden Störungen eingesetzt. Die vorliegende narrative systematische Übersichtsarbeit beschreibt den Stand der Forschung zu transdiagnostischen Behandlungskonzepten in Hinsicht auf Angst- und komorbide Störungen. Methode: Die Literaturrecherche und die Datenanalyse wurden angelehnt an die PRISMA Guidelines vorgenommen. Die Ergebnisse von 17 Untersuchungen zu expositionsbasierten transdiagnostischen Behandlungskonzepten der letzten fünfzehn Jahre werden beschrieben. Ergebnisse: Die Resultate der referierten Studien zeigen, dass expositionsbasierte transdiagnostische Behandlungen die Symptome, sowohl der primären als auch der komorbiden Störungen, signifikant reduzieren. Expositionsbasierte transdiagnostische Konzepte sind effektiv zur Behandlungen von Angststörungen und komorbider Störungen. Sie stellen eine geeignete Alternative zu störungsspezifischen Behandlungen dar. Diskussion: Die Implikationen transdiagnostischer Konzepte für das praktische Vorgehen bei der individualisierten Diagnostik, der Vorbereitung und Durchführung von Expositionen werden erörtert. Schließlich werden Vorschläge für die Konzeptualisierung einer störungsübergreifenden Behandlung von Angststörungen, insbesondere solcher mit komorbider Symptomatik, vorgestellt.


Transdiagnostic Exposure-Based Treatments of Anxiety Disorders: Implications for Clinical Practice

Abstract.Background: Besides disorder-specific cognitive behavioral therapy (CBT) concepts, transdiagnostic cognitive-behavioral treatments have been increasingly used in exposure-based therapy of anxiety and comorbid disorders in recent years. This systematic narrative review provides the state of research on transdiagnostic CBT of anxiety and comorbid disorders. Methods: Research findings from 17 studies concerning exposure-based transdiagnostic treatments of the last 15 years are presented and discussed. The literature search and data analysis were conducted accordingly to the PRISMA Guidelines. Results: The results of the reviewed studies show that exposure-based transdiagnostic treatments reduce the symptoms of both principal and comorbid disorders. Transdiagnostic methods are effective for the treatment of anxiety and comorbid disorders and are an adequate alternative to disorder-specific treatments. Discussion: The implications of transdiagnostic CBT concepts in the individual diagnosis, preparation, and implementation of exposure are discussed. In conclusion, suggestions for the conceptualization of a transdiagnostic treatment for comorbid anxiety disorders are presented.

Literatur

  • Abramowitz, J. S. (1996). Variants of exposure and response prevention in the treatment of obsessive-compulsive disorder: A meta-analysis. Behavior Therapy, 27, 583 – 600. First citation in articleCrossrefGoogle Scholar

  • Abramowitz, J. S., Deacon, B. & Whiteside, R. (2011). Exposure therapy for anxiety. New York: Guilford Press. First citation in articleGoogle Scholar

  • Arnfred, S. M., Aharoni, R., Hvenegaard, M., Poulsen, S., Bach, B. & Arendt, M., et al. (2017). Transdiagnostic group CBT vs. standard group CBT for depression, social anxiety disorder and agoraphobia / panic disorder: Study protocol for a pragmatic, multicenter non-inferiority randomized controlled trial. BMC Psychiatry, 17, 37. First citation in articleCrossrefGoogle Scholar

  • Bandelow, B., Lichte, T., Rudolf, S., Wiltink, J. & Beutel, M. (Hrsg.). (2014). S3-Leitlinie Angststörungen. Berlin, Heidelberg: Springer. First citation in articleGoogle Scholar

  • Barlow, D. H. (1990). Long-term outcome for patients with panic disorder treated with cognitive therapy. Journal of Clinical Psychology, 51, 17 – 23. First citation in articleGoogle Scholar

  • Barlow, D. H., Allen, L. B. & Choate, M. L. (2016). Toward a unified treatment for emotional disorders – republished article. Behavior Therapy , 47, 838 – 853. First citation in articleCrossrefGoogle Scholar

  • Barlow, D. H., Ellard, K. K., Fairholme, C. P., Farchione, T. J., Boisseau, C. L., Allen, L. B. et al. (2004). The unified protocol for transdiagnostic treatment of emotional disorders. New York: Oxford Press. First citation in articleGoogle Scholar

  • Barlow, D. H., Farchione, T. J., Sauer-Zavala, S., Latin, H. M., Ellard, K. K. & Bullis, J. R., et al. (2017). Unified protocol for transdiagnostic treatment of emotional disorders: Therapist guide. New York, NY: Oxford University Press. First citation in articleGoogle Scholar

  • Becker, E. & Hoyer, J. (2005). Generalisierte Angststörung (Fortschritte der Psychotherapie). Göttingen: Hogrefe. First citation in articleGoogle Scholar

  • Becker, C. B., Zayfert, C. & Anderson, E. (2004). A survey of psychologists’ attitudes towards and utilization of exposure therapy for PTSD. Behaviour Research and Therapy, 42, 277 – 292. First citation in articleCrossrefGoogle Scholar

  • Boettcher, H., Brake, C. A. & Barlow, D. H. (2016). Origins and outlook of interoceptive exposure. Journal of Behavior Therapy and Experimental Psychiatry, 53, 41 – 51. First citation in articleCrossrefGoogle Scholar

  • Böhm, K., Förstner, U., Külz, A. & Voderholzer, U. (2008). Versorgungsrealität der Zwangsstörungen: Werden Expositionsverfahren eingesetzt? Verhaltenstherapie, 18, 18 – 24. First citation in articleCrossrefGoogle Scholar

  • Borkovec, T. D. & Costello, E. (1993). Efficacy of applied relaxation and cognitive-behavioral therapy in the treatment of generalized anxiety disorder. Journal of Consulting and Clinical Psychology, 61, 611 – 619. First citation in articleCrossrefGoogle Scholar

  • Boswell, J. F., Farchione, T. J., Sauer-Zavala, S., Murray, H. W., Fortune, M. R. & Barlow, D. H. (2013). Anxiety sensitivity and interoceptive exposure: a transdiagnostic construct and change strategy. Behavior Therapy, 44, 417 – 431. First citation in articleCrossrefGoogle Scholar

  • Brown, T. A., Campbell, L. A., Lehman, C. L., Grisham, J. R. & Mancill, R. B. (2001). Current and lifetime comorbidity of the DSM-IV anxiety and mood disorders in a large clinical sample. Journal of Abnormal Psychology, 110, 585 – 599. First citation in articleCrossrefGoogle Scholar

  • Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Hillsdale, NJ: Erlbaum. First citation in articleGoogle Scholar

  • Clark, L. A. & Watson, D. (1991). Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications. Journal of Abnormal Psychology, 100, 316 – 336. First citation in articleCrossrefGoogle Scholar

  • Clark, L. A., Watson, D. & Mineka, S. (1994). Temperament, personality, and the mood and anxiety disorders. Journal of Abnormal Psychology, 103, 103 – 116. First citation in articleCrossrefGoogle Scholar

  • Craske, M. G. & Barlow, D. H. (2006). Mastery of your anxiety and worry. New York: Oxford University Press. First citation in articleCrossrefGoogle Scholar

  • Craske, M. G. & Barlow, D. H. (2007). Mastery of your anxiety and panic: Therapist guide. New York: Oxford University Press. First citation in articleGoogle Scholar

  • Craske, M. G. & Mystowski, J. L. (2006). Exposure therapy and extinction: clinical studies. In M. G. CraskeD. HermansD. VansteenwegenEds., Fear and learning: Basic science to clinical application (pp. 217 – 233). Washington DC: APA Books. First citation in articleGoogle Scholar

  • Craske, M. G., Treanor, M., Conway, C. C., Zboznek, T. & Vervliet, B. (2008). Maximizing exposure therapy an inhibitory learning approach. Behavior Research and Therapy, 58, 10 – 23. First citation in articleCrossrefGoogle Scholar

  • Deacon, B. J. (2012). The ethics of exposure therapy for anxiety disorders. In P. NeudeckH. U. WittchenEds., Exposure therapy: Rethinking the model - refining the method (pp. 9 – 22). New York: Springer Press. First citation in articleGoogle Scholar

  • Dugas, M. J., Freeston, M. H. & Ladouceur, R. (1997). Intolerance of uncertainty and problem orientation in worry. Cognitive Therapy and Research, 21, 593 – 606. First citation in articleCrossrefGoogle Scholar

  • Dugas, M. J. & Robichaud, M. (2007). Cognitive-behavioral treatment for generalized anxiety disorder: From science to practice. New York, NY: Taylor & Francis. First citation in articleGoogle Scholar

  • Ellard, K. K., Fairholme, C. P., Boisseau, C. L., Farchione, T. J. & Barlow, D. H. (2010). Unified protocol for the transdiagnostic treatment of emotional disorders: Protocol development and initial outcome data. Cognitive and Behavioral Practice, 17, 88 – 101. First citation in articleCrossrefGoogle Scholar

  • Erickson, D. H., Janeck, A. S. & Tallman, K. (2007). A cognitive-behavioral group for patients with various anxiety disorders. Psychiatric Services, 58, 1205 – 1211. First citation in articleCrossrefGoogle Scholar

  • Farchione, T. J., Fairholme, C. P., Ellard, K. K., Boisseau, C. L., Thompson-Hollands, J. & Carl, J. R., et al. (2012). Unified protocol for transdiagnostic treatment of emotional disorders: a randomized controlled trial. Behavior Therapy, 43, 666 – 678. First citation in articleCrossrefGoogle Scholar

  • Fedoroff, I. C. & Taylor, S. (2001). Psychological and pharmacological treatments of social phobia: a meta-analysis. Journal of Clinical Psychopharmacology, 21, 311 – 324. First citation in articleCrossrefGoogle Scholar

  • Foa, E. B., Hembree, E. A., Cahill, S. P., Rauch, S. A., Riggs, D. S. & Feeny, N. C., et al. (2005). Randomized trial of prolonged exposure for posttraumatic stress disorder with and without cognitive restructuring: outcome at academic and community clinics. Journal of Consulting and Clinical Psychology, 73, 953 – 964. First citation in articleCrossrefGoogle Scholar

  • Franklin, M. E., Abramowitz, J. S., Kozak, M. J., Levitt, J. T. & Foa, E. B. (2000). Effectiveness of exposure and ritual prevention for obsessive-compulsive disorder: randomized compared with nonrandomized samples. Journal of Consulting and Clinical Psychology, 68, 594 – 602. First citation in articleCrossrefGoogle Scholar

  • Gerlach, A. & Neudeck, P. (2012). Interozeptive Exposition. In P. NeudeckH. U. WittchenEds., Exposure Therapy. Rethinking the Model, Refining the Method (pp. 191 – 192). Heidelberg: Springer Science & Business Media. First citation in articleGoogle Scholar

  • Gloster, A. T., Wittchen, H. U., Einsle, F., Höfler, M., Lang, T. & Helbig-Lang, S., et al. (2009). Mechanism of action in CBT (MAC): methods of a multi-center randomized controlled trial in 369 patients with panic disorder and agoraphobia. European Archives of Psychiatry and Clinical Neuroscience, 259 (Suppl 2), 155 – 166. First citation in articleCrossrefGoogle Scholar

  • Grillon, C. (2002). Startle reactivity and anxiety disorders: aversive conditioning, context, and neurobiology. Biological Psychiatry, 52, 958 – 975. First citation in articleCrossrefGoogle Scholar

  • Hamm, A. (2006). Spezifische Phobien (Fortschritte der Psychotherapie). Göttingen: Hogrefe. First citation in articleGoogle Scholar

  • Hamm, A., Wendt, J. & Volkmann, M. (2017). Extinktion: Neurowissenschaftliche Erkenntnisse zur Frage, wie Menschen sich ändern. Verhaltenstherapie, 27, 16 – 26. First citation in articleCrossrefGoogle Scholar

  • Heimberg, R. G. & Becker, R. E. (2002). Cognitive-behavioral group therapy for social phobia: Basic mechanisms and clinical strategies. New York: Guilford Press. First citation in articleGoogle Scholar

  • Heinig, I., Pittig, A., Richter, J., Hummel, K., Alt, I. & Dickhöver, K., et al. (2017). Optimizing exposure‐based CBT for anxiety disorders via enhanced extinction: Design and methods of a multicentre randomized clinical trial. International Journal of Methods in Psychiatric Research, 26, e1560. https://doi.org/10.1002/mpr.1560 First citation in articleCrossrefGoogle Scholar

  • Hoffmann, N. & Hofmann, A. (2012). Exposition bei Ängsten und Zwängen. Weinheim: Beltz. First citation in articleGoogle Scholar

  • Hofmann, S. G. (2014). Toward a cognitive-behavioral classification system for mental disorders. Behavior Therapy, 45, 576 – 587. https://doi.org/10.1016/j.beth.2014.03.001 First citation in articleCrossrefGoogle Scholar

  • Hope, D. A., Heimberg, R. G. & Turk, C. L. (2006). Managing social anxiety: Therapist guide: A cognitive-behavioral therapy approach (treatments that work). New York: Oxford Press. First citation in articleGoogle Scholar

  • Hoyer, J., Čolić, J., Pittig, A., Crawcour, S., Ginzburg, D. & Moeser, M., et al. (2017). Manualized cognitive therapy versus cognitive-behavioral treatment-as-usual for social anxiety disorder in routine practice: A cluster-randomized controlled trial. Behaviour Research and Therapy, 95, 87 – 98. First citation in articleCrossrefGoogle Scholar

  • Insel, T., Cuthbert, B., Garvey, M., Heinssen, R., Pine, D. S. & Quinn, K., et al. (2010). Research domain criteria (RDoC): toward a new classification framework for research on mental disorders. American Journal of Psychiatry, 167, 748 – 751. First citation in articleCrossrefGoogle Scholar

  • Ito, M., Okumura, Y., Horikoshi, M., Kato, N., Oe, Y. & Miyamae, M., et al. (2016). Japan Unified Protocol Clinical Trial for Depressive and Anxiety Disorders (JUNP study): study protocol for a randomized controlled trial. BMC Psychiatry, 16, 71. First citation in articleCrossrefGoogle Scholar

  • Keller, M. B. (2002). The long-term clinical course of generalized anxiety disorder. The Journal of Clinical Psychiatry, 63, 11 – 16. First citation in articleGoogle Scholar

  • Kristjánsdóttir, H., Salkovskis, P. M., Sigurdsson, B. H., Sigurdsson, E., Agnarsdóttir, A. & Sigurdsson, J. F. (2015). Transdiagnostic cognitive behavioural treatment and the impact of co-morbidity: An open trial in a cohort of primary care patients. Nordic Journal of Psychiatry, 70, 215 – 223. First citation in articleCrossrefGoogle Scholar

  • Lang, T., Helbig-Lang, S., Westphal, D., Gloster, A. T. & Wittchen, H. U. (2012). Expositionsbasierte Therapie der Panikstörung mit Agoraphobie. Ein Behandlungsmanual. Göttingen: Hogrefe. First citation in articleGoogle Scholar

  • Margraf, J. & Schneider, S. (2005). Panik: Angstanfälle und ihre Behandlung. Heidelberg: Springer. First citation in articleGoogle Scholar

  • McEvoy, P. M. & Nathan, P. (2007). Effectiveness of cognitive behavior therapy for diagnostically heterogeneous groups: A benchmarking study. Journal of Consulting and Clinical Psychology, 75, 344 – 350. First citation in articleCrossrefGoogle Scholar

  • Mohammadi, A., Birashk, B. & Gharaie, B. (2013). Comparison of the effect of group transdiagnostic therapy and group cognitive therapy on anxiety and depressive symptoms. Iranian Journal of Public Health, 42, 48 – 55. First citation in articleGoogle Scholar

  • Neudeck, P. (2015). Expositionsverfahren (Techniken der Verhaltenstherapie). Weinheim: Beltz. First citation in articleGoogle Scholar

  • Neudeck, P. & Einsle, F. (2010). Expositionstherapie: was hindert Praktiker an deren Anwendung in der klinischen Praxis? – ein kritischer Review. Verhaltenstherapie & Verhaltensmedizin, 2010 (3), 247 – 258. First citation in articleGoogle Scholar

  • Neudeck, P. & Wittchen, H. U. (Hrsg.). (2012). Konfrontationstherapie bei psychischen Störungen: Theorie und Praxis. Göttingen: Hogrefe. First citation in articleGoogle Scholar

  • Newby, J. M., McKinnon, A., Kuyken, W., Gilbody, S. & Dalgleish, T. (2015). Systematic review and meta-analysis of transdiagnostic psychological treatments for anxiety and depressive disorders in adulthood. Clinical Psychology Review, 40, 91 – 110. First citation in articleCrossrefGoogle Scholar

  • Newman, M. G., Castonguay, L. G., Borkovec, T. D., Fisher, A. J. & Nordberg, S. S. (2008). An open trial of integrative therapy for generalized anxiety disorder. Psychotherapy: Theory, Research, Practice, Training, 45 (2), 135 – 147. First citation in articleCrossrefGoogle Scholar

  • Norton, P. J. (2008). An open trial of a transdiagnostic cognitive-behavioral group therapy for anxiety disorder. Behavior Therapy, 39, 242 – 250. First citation in articleCrossrefGoogle Scholar

  • Norton, P. J. (2012). A randomized clinical trial of transdiagnostic cognitve-behavioral treatments for anxiety disorder by comparison to relaxation training. Behavior Therapy, 43, 506 – 517. First citation in articleCrossrefGoogle Scholar

  • Norton, P. J. & Barrera, T. L. (2012). Transdiagnostic versus diagnosis‐specific CBT for anxiety disorders: A preliminary randomized controlled noninferiority trial. Depression and Anxiety, 29, 874 – 882. First citation in articleCrossrefGoogle Scholar

  • Norton, P. J., Barrera, T. L., Mathew, A. R., Chamberlain, L. D., Szafranski, D. D. & Reddy, R., et al. (2013). Effect of transdiagnostic CBT for anxiety disorders on comorbid diagnoses. Depression and Anxiety, 30, 168 – 173. First citation in articleCrossrefGoogle Scholar

  • Norton, P. J., Hayes, S. A. & Hope, D. A. (2004). Effects of a transdiagnostic group treatment for anxiety on secondary depression. Depression and Anxiety, 20, 198 – 202. First citation in articleCrossrefGoogle Scholar

  • Norton, P. J. & Hope, D. A. (2005). Preliminary evaluation of a broad-spectrum cognitive-behavioral group therapy for anxiety. Journal of Behavior Therapy and Experimental Psychiatry, 36 (2), 79 – 97. First citation in articleCrossrefGoogle Scholar

  • Norton, P. J. & Hope, D. A. (2008). The „Anxiety Treatment Protocol“ A group case study demonstration of a transdiagnostic group cognitive-behavioral therapy for anxiety disorders. Clinical Case Studies, 7, 538 – 554. First citation in articleCrossrefGoogle Scholar

  • Norton, P. J. & Philipp, L. M. (2008). Transdiagnostic approaches to the treatment of anxiety disorders: A quantitative review. Psychotherapy: Theory, Research, Practice, Training, 45, 214 – 226. First citation in articleCrossrefGoogle Scholar

  • Olatunji, B. O., Cisler, J. M. & Deacon, B. J. (2010). Efficacy of cognitive behavioral therapy for anxiety disorders: a review of meta-analytic findings. Psychiatric Clinics of North America, 33, 557 – 577. First citation in articleCrossrefGoogle Scholar

  • Păsărelu, C. R., Andersson, G., Bergman Nordgren, L. & Dobrean, A. (2016). Internet-delivered transdiagnostic and tailored cognitive behavioral therapy for anxiety and depression: a systematic review and meta-analysis of randomized controlled trials. Cognitive Behaviour Therapy, 46, 1 – 28. First citation in articleCrossrefGoogle Scholar

  • Pearl, S. B. & Norton, P. J. (2017). Transdiagnostic versus diagnosis specific cognitive behavioural therapies for anxiety: A meta-analysis. Journal of Anxiety Disorders, 46, 11 – 24. First citation in articleCrossrefGoogle Scholar

  • Pittig, A. & Hoyer, J. (2018). Exposition aus Sicht niedergelassener Verhaltenstherapeutinnen und Verhaltenstherapeuten. Anwendung und systemische Barrieren. Zeitschrift für Klinische Psychologie und Psychotherapie, 46, 223 – 235. First citation in articleLinkGoogle Scholar

  • Rector, N. A., Man, V. & Lerman, B. (2014). The expanding cognitive-behavioural therapy treatment umbrella for the anxiety disorders: disorder-specific and transdiagnostic approaches. The Canadian Journal of Psychiatry, 59, 301 – 309. First citation in articleCrossrefGoogle Scholar

  • Reinholt, N. & Krogh, J. (2014). Efficacy of transdiagnostic cognitive behaviour therapy for anxiety disorders: A systematic review and meta-analysis of published outcome studies. Cognitive Behaviour Therapy, 43, 171 – 184. First citation in articleCrossrefGoogle Scholar

  • Rodriguez, B. F., Weisberg, R. B., Pagano, M. E., Machan, J. T., Culpepper, L. & Keller, M. B. (2004). Frequency and patterns of psychiatric comorbidity in a sample of primary care patients with anxiety disorders. Comprehensive Psychiatry, 45 (2), 129 – 137. First citation in articleCrossrefGoogle Scholar

  • Roemer, L, Orsillo, S. M. & Salters-Pedneault, K. (2008). Efficacy of an acceptance-based behavior therapy for generalized anxiety disorder: Evaluation in a randomized controlled trial. Journal of Consulting and Clinical Psychology, 76, 1083 – 1089. First citation in articleCrossrefGoogle Scholar

  • Rosa-Alcázar, A. I., Sánchez-Meca, J., Gómez-Conesa, A. & Marín-Martínez, F. (2008). Psychological treatment of obsessive-compulsive disorder: a meta-analysis. Clinical Psychology Review, 28, 1310 – 1325. First citation in articleCrossrefGoogle Scholar

  • Ruhmland, M. & Margraf, J. (2001a). Effektivität psychologischer Therapien von spezifischer Phobie und Zwangsstörung: Metaanalysen auf Störungsebene. Verhaltenstherapie, 11, 14 – 26. First citation in articleCrossrefGoogle Scholar

  • Ruhmland, M. & Margraf, J. (2001b). Effektivität psychologischer Therapien von generalisierter Angststörung und sozialer Phobie: Metaanalysen auf Störungsebene. Verhaltenstherapie, 11, 27 – 40. First citation in articleCrossrefGoogle Scholar

  • Ruhmland, M. & Margraf, J. (2001c). Effektivität psychologischer Therapien von Panik und Agoraphobie: Metaanalysen auf Störungsebene. Verhaltenstherapie, 11, 41 – 53. First citation in articleCrossrefGoogle Scholar

  • Schmidt-Traub, S. (2014). Panikstörung und Agoraphobie. Ein Therapiemanual (Therapeutische Praxis, Bd. 1). Göttingen: Hogrefe. First citation in articleGoogle Scholar

  • Schmucker, C., Motschall, E., Antes, G. & Meerpohl, J. J. (2013). Methoden des Evidence Mappings. Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz, 56, 1390 – 1397. First citation in articleCrossrefGoogle Scholar

  • Stangier, U., Heidenreich, T. & Peitz, M. (2009). Soziale Phobien: Ein kognitiv-verhaltenstherapeutisches Behandlungsmanual. Weinheim: Beltz. First citation in articleGoogle Scholar

  • Talkovsky, A. M. & Norton, P. J. (2014). Mediators of transdiagnostic group cognitive behavior therapy. Journal of Anxiety Disorders, 28, 919 – 924. First citation in articleCrossrefGoogle Scholar

  • Talkovsky, A. M. & Norton, P. J. (2016). Intolerance of uncertainty and transdiagnostic group cognitive behavioral therapy for anxiety. Journal of Anxiety Disorders, 41, 108 – 114. First citation in articleCrossrefGoogle Scholar

  • Wells, A. (2008). Metacognitive Therapy for Worry and Generalised Anxiety Disorder. In G. C. L. DaveyA. WellsEds., Worry and its Psychological Disorders: Theory, Assessment and Treatment (Chapter 15, pp. 259 – 272). Chichester, UK: John Wiley & Sons Ltd. https://doi.org/10.1002/9780470713143.ch15 First citation in articleGoogle Scholar

  • Wells, A., Clark, D. M., Salkovskis, P., Ludgate, J., Hackmann, A. & Gelder, M. (1995). Social phobia: The role of in-situation safety behaviors in maintaining anxiety and negative beliefs. Behavior Therapy, 26, 153 – 161. First citation in articleCrossrefGoogle Scholar