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Full-Length Research Report

Facets of Subjective Health Horizons Are Differentially Linked to Brain Volume

Published Online:June 25, 2018https://doi.org/10.1024/1662-9647/a000191

Abstract

Abstract. An active lifestyle including physical exercise and novelty processing is considered to promote brain health. Also, subjective future time perspectives (FTP) are known to shape motivation and goal-directed behavior, with links to objective health, well-being, and cognition. Nevertheless, the links between subjective FTP and brain physiology are largely unknown. We report data from 326 healthy older adults who completed the Subjective Health Horizon Questionnaire (SHH-Q) and structural magnetic resonance imaging (MRI). Voxel-based morphometry analyses revealed associations between (1) the SHH-Q Novelty factor and brain regions of the episodic memory network, and (2) the SHH-Q Body factor and regions contributing to the cortical representation of bodily states. Longitudinal and experimental data are needed to better understand the etiology of these links.

References

  • Addis, D., Wong, A., & Schacter, D. (2007). Remembering the past and imagining the future: Common and distinct neural substrates during event construction and elaboration. Neuropsychologia, 45, 1363–1377. doi 10.1016/j.neuropsychologia.2006.10.016 First citation in articleCrossref, Google Scholar

  • Arzy, S., Collette, S., Ionta, S., Fornari, E., & Blanke, O. (2009). Subjective mental time: The functional architecture of projecting the self to past and future. The European Journal of Neuroscience, 30, 2009–2017. doi 10.1111/j.1460-9568.2009.06974.x First citation in articleCrossref, Google Scholar

  • Ashburner, J., & Friston, K. J. (2000). Voxel-based morphometry: The methods. NeuroImage, 11, 805–821. doi 10.1006/nimg.2000.0582 First citation in articleCrossref, Google Scholar

  • Benoit, R., & Schacter, D. (2015). Specifying the core network supporting episodic simulation and episodic memory by activation likelihood estimation. Neuropsychologia, 75, 450–457. doi 10.1016/j.neuropsychologia.2015.06.034 First citation in articleCrossref, Google Scholar

  • Bertram, L., Böckenhoff, A., Demuth, I., Düzel, S., Eckardt, R., Li, S.-C. C., ... Steinhagen-Thiessen, E. (2014). Cohort profile: The Berlin Aging Study II (BASE-II). International Journal of Epidemiology, 43, 703–712. doi 10.1093/ije/dyt018 First citation in articleCrossref, Google Scholar

  • Brandtstädter, J., & Greve, W. (1994). The aging self: Stabilizing and protective processes. Developmental Review, 52–80. doi 10.1006/drev.1994.1003 First citation in articleCrossref, Google Scholar

  • Brandtstädter, J., & Rothermund, K. (2002). The life-course dynamics of goal pursuit and goal adjustment: A two-process framework. Developmental Review, 22, 117–150. doi 10.1006/drev.2001.0539 First citation in articleCrossref, Google Scholar

  • Brandtstädter, J., Rothermund, K., Kranz, D., & Kühn, W. (2010). Final decentrations – personal goals, rationality perspectives, and the awareness of life’s finitude. European Psychologist, 15, 152–163. doi 10.1027/1016-9040/a000019 First citation in articleLink, Google Scholar

  • Buckner, R., Andrews-Hanna, J., & Schacter, D. (2008). The brain’s default network: Anatomy, function, and relevance to disease. Annals of the New York Academy of Sciences, 1124, 1–38. doi 10.1196/annals.1440.011 First citation in articleCrossref, Google Scholar

  • Bulganin, L., & Wittmann, B. (2015). Reward and novelty enhance imagination of future events in a motivational-episodic network. PLoS ONE, 10(11), e0143477. doi 10.1371/journal.pone.0143477 First citation in articleGoogle Scholar

  • Carstensen, L., & Lang, FR. (1996). Future Time Perspective Scale. Stanford, CA: Stanford University Press. First citation in articleGoogle Scholar

  • Craig, A. D. (2002). How do you feel? Interoception: The sense of the physiological condition of the body. Nature Reviews Neuroscience, 3, 655–666. doi 10.1038/nrn894 First citation in articleCrossref, Google Scholar

  • Craig, A. D. (2003). Interoception: The sense of the physiological condition of the body. Current Opinion in Neurobiology, 13, 500–505. First citation in articleCrossref, Google Scholar

  • Di Lernia, D., Serino, S., & Riva, G. (2017). Pain in the body: Altered interoception in chronic pain conditions. A systematic review. Neuroscience and Biobehavioral Reviews, 71, 328–341. doi 10.1016/j.neubiorev.2016.09.015 First citation in articleCrossref, Google Scholar

  • Droit-Volet, S. (2013). Time perception, emotions and mood disorders. Journal of Physiology, 107, 255–264. doi 10.1016/ j.jphysparis.2013.03.005 First citation in articleGoogle Scholar

  • Düzel, E., Bunzeck, N., Guitart-Masip, M., & Düzel, S. (2010). NOvelty-related Motivation of Anticipation and exploration by Dopamine (NOMAD): Implications for healthy aging. Neuroscience and Biobehavioral Reviews, 34, 660–669. doi 10.1016/j.neubiorev. 2009.08.006 First citation in articleCrossref, Google Scholar

  • Düzel, S., Voelkle, M. C., Düzel, E., Gerstorf, D., Drewelies, J., Steinhagen-Thiessen, E., ... Lindenberger, U. (2016). The Subjective Health Horizon Questionnaire (SHH-Q): Assessing future time perspectives for facets of an active lifestyle. Gerontology, 62, 345–353. doi 10.1159/000441493 First citation in articleCrossref, Google Scholar

  • Good, C. D., Johnsrude, I. S., Ashburner, J., Henson, R. N., Friston, K. J., & Frackowiak, R. S. (2001). A voxel-based morphometric study of aging in 465 normal adult human brains. NeuroImage, 14, 21–36. doi 10.1006/nimg.2001.0786 First citation in articleCrossref, Google Scholar

  • Hassabis, D., Kumaran, D., & Maguire, E. (2007). Using imagination to understand the neural basis of episodic memory. The Journal of Neuroscience, 27, 14365–14374. doi 10.1523/jneurosci.4549-07.2007 First citation in articleCrossref, Google Scholar

  • Hassabis, D., Kumaran, D., Vann, S., & Maguire, E. (2007). Patients with hippocampal amnesia cannot imagine new experiences. Proceedings of the National Academy of Sciences of the United States of America, 104, 1726–1731. doi 10.1073/pnas.0610561104 First citation in articleCrossref, Google Scholar

  • Hassabis, D., & Maguire, E. (2007). Deconstructing episodic memory with construction. Trends in Cognitive Sciences, 11, 299–306. doi 10.1016/j.tics.2007.05.001 First citation in articleCrossref, Google Scholar

  • Hayasaka, S., & Nichols, T. E. (2004). Combining voxel intensity and cluster extent with permutation test framework. NeuroImage, 23, 54–63. doi 10.1016/j.neuroimage.2004.04.035 First citation in articleCrossref, Google Scholar

  • Heckhausen, J., Wrosch, C., & Schulz, R. (2010). A motivational theory of lifespan development. Psychological Review, 117, 32–60. doi 10.1037/a0017668 First citation in articleCrossref, Google Scholar

  • Hertzog, C., Kramer, A., Wilson, R., & Lindenberger, U. (2008). Enrichment effects on adult cognitive development: Can the functional capacity of older adults be preserved and enhanced? Psychological Science in the Public Interest, 9, 1–65. doi 10.1111/j.1539-6053.2009.01034.x First citation in articleCrossref, Google Scholar

  • Infurna, F., & Gerstorf, D. (2013). Linking perceived control, physical activity, and biological health to memory change. Psychology and Aging, 28, 1147–1163. doi 10.1037/a0033327 First citation in articleCrossref, Google Scholar

  • Kozik, P., Hoppmann, C., & Gerstorf, D. (2014). Future time perspective: Opportunities and limitations are differentially associated with subjective well-being and hair cortisol concentration. Gerontology, 61, 166–174. doi 10.1159/000368716 First citation in articleCrossref, Google Scholar

  • Lang, F., & Carstensen, L. (2002). Time counts: Future time perspective, goals, and social relationships. Psychology and Aging, 17, 125–39. First citation in articleCrossref, Google Scholar

  • Lindenberger, U. (2014). Human cognitive aging: Corriger la fortune? Science, 346(6209), 572–578. doi 10.1126/science. 1254403 First citation in articleCrossref, Google Scholar

  • Lindenberger, U., Wenger, E., & Lövdén, M. (2017). Toward a stronger science of human plasticity. Nature Reviews Neuroscience, 18, 261–262. doi 10.1038/nrn.2017.44 First citation in articleCrossref, Google Scholar

  • Lisman, J., & Grace, A. (2005). The hippocampal-VTA loop: Controlling the entry of information into long-term memory. Neuron, 46, 703–713. doi 10.1016/j.neuron.2005.05.002 First citation in articleCrossref, Google Scholar

  • Lisman, J., Grace, A., & Duzel, E. (2011). A neo-Hebbian framework for episodic memory: Role of dopamine-dependent late LTP. Trends in Neurosciences, 34, 536–547. doi 10.1016/j.tins.2011.07.006 First citation in articleCrossref, Google Scholar

  • Maguire, E. A. (2001). The retrosplenial contribution to human navigation: a review of lesion and neuroimaging findings. Scandinavian Journal of Psychology, 42, 225–238. First citation in articleCrossref, Google Scholar

  • Maguire, E. A., Spiers, H. J., Good, C. D., Hartley, T., Frackowiak, R. S., & Burgess, N. (2003). Navigation expertise and the human hippocampus: A structural brain imaging analysis. Hippocampus, 13, 250–259. doi 10.1002/hipo.10087 First citation in articleCrossref, Google Scholar

  • Mathalon, D. H., Sullivan, E. V., Rawles, J. M., & Pfefferbaum, A. (1993). Correction for head size in brain-imaging measurements. Psychiatry Research, 50, 121–139. First citation in articleCrossref, Google Scholar

  • Mather, M., & Carstensen, L. (2003). Aging and attentional biases for emotional faces. Psychological Science, 14, 409–415. doi 10.1111/1467-9280.01455 First citation in articleCrossref, Google Scholar

  • Mather, M., & Carstensen, L. L. (2005). Aging and motivated cognition: The positivity effect in attention and memory. Trends in Cognitive Sciences, 9, 496–502. doi 10.1016/j.tics.2005.08.005 First citation in articleCrossref, Google Scholar

  • Mather, M., & Schoeke, A. (2011). Positive outcomes enhance incidental learning for both younger and older adults. Frontiers in Neuroscience, 5, 129. doi 10.3389/fnins.2011.00129 First citation in articleCrossref, Google Scholar

  • Muthén, L. K., & Muthén, B. O. (2010). Mplus user’s guide. (6th ed.). Los Angeles: Author. First citation in articleGoogle Scholar

  • Nestor, P., Fryer, T., Smielewski, P., & Hodges, J. (2003). Limbic hypometabolism in Alzheimer’s disease and mild cognitive impairment. Annals of Neurology, 54, 343–351. doi 10.1002/ana.10669 First citation in articleCrossref, Google Scholar

  • Nyberg, L., Kim, A. S., Habib, R., Levine, B., & Tulving, E. (2010). Consciousness of subjective time in the brain. Proceedings of the National Academy of Sciences of the United States of America, 107, 22356–22359. doi 10.1073/pnas.1016823108 First citation in articleCrossref, Google Scholar

  • Raz, N., & Lindenberger, U. (2013). Life-span plasticity of the brain and cognition: From questions to evidence and back. Neuroscience and Biobehavioral Reviews, 37, 2195–2200. doi 10.1016/j.neubiorev.2013.10.003 First citation in articleCrossref, Google Scholar

  • Raz, N., & Rodrigue, K. (2006). Differential aging of the brain: Patterns, cognitive correlates and modifiers. Neuroscience and Biobehavioral Reviews, 30, 730–748. doi 10.1016/j.neubiorev.2006.07.001 First citation in articleCrossref, Google Scholar

  • Rowe, J. W., & Kahn, R. L. (2015). Successful aging 20: Conceptual expansions for the 21st century. The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences, 70, 593–596. doi 10.1093/geronb/gbv025 First citation in articleCrossref, Google Scholar

  • Schacter, D. L., Addis, D. R., & Buckner, R. L. (2008). Episodic simulation of future events: Concepts, data, and applications. Annals of the New York Academy of Sciences, 1124, 39–60. doi 10.1196/annals.1440.001 First citation in articleCrossref, Google Scholar

  • Schacter, D. L., Addis, D. R., Hassabis, D., Martin, V. C., Spreng, R. N., & Szpunar, K. K. (2012). The future of memory: Remembering, imagining, and the brain. Neuron, 76, 677–694. doi 10.1016/j.neuron.2012.11.001 First citation in articleCrossref, Google Scholar

  • Szpunar, K. K., Watson, J. M., & McDermott, K. B. (2007). Neural substrates of envisioning the future. Proceedings of the National Academy of Sciences of the United States of America, 104, 642–647. doi 10.1073/pnas.0610082104 First citation in articleCrossref, Google Scholar

  • Van Praag, H., Kempermann, G., & Gage, F. H. (2000). Neural consequences of environmental enrichment. Nature Reviews Neuroscience, 1, 191–198. doi 10.1038/35044558 First citation in articleCrossref, Google Scholar

  • Vann, S., Aggleton, J., & Maguire, E. (2009). What does the retrosplenial cortex do? Nature Reviews Neuroscience, 10, 792–802. doi 10.1038/nrn2733 First citation in articleCrossref, Google Scholar

  • Wheeler, M. A., Stuss, D. T., & Tulving, E. (1997). Toward a theory of episodic memory: The frontal lobes and autonoetic consciousness. Psychological Bulletin, 121, 331–354. First citation in articleCrossref, Google Scholar

  • Whitwell, J. L., Crum, W. R., Watt, H. C., & Fox, N. C. (2001). Normalization of cerebral volumes by use of intracranial volume: Implications for longitudinal quantitative MR imaging. American Journal of Neuroradiology, 22, 1483–1489. First citation in articleGoogle Scholar

  • Wittmann, B., Bunzeck, N., Dolan, R., & Düzel, E. (2007). Anticipation of novelty recruits reward system and hippocampus while promoting recollection. NeuroImage, 38, 194–202. doi 10.1016/j.neuroimage.2007.06.038 First citation in articleCrossref, Google Scholar