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Soziale Kognition bei Autismus-Spektrum-Störungen und Störungen des Sozialverhaltens

Published Online:https://doi.org/10.1026/0942-5403/a000125

Soziale Kognition umfasst eine Reihe von impliziten und expliziten Informationsverarbeitungsprozessen, die im Rahmen der sozialen Interaktion stattfinden, wie zum Beispiel die implizite Aufmerksamkeitszuwendung, die Emotionserkennung oder die Theory of Mind. Defizite in der sozialen Kognition werden im Zusammenhang mit Störungsbildern, zu deren Kernsymptomatik eine Störung in der sozialen Interaktion zählt, angenommen, darunter Autismus-Spektrum-Störungen (ASS) und Störungen des Sozialverhaltens (SSV). Die vorliegende Übersichtsarbeit gibt einen Einblick in den derzeitigen Forschungsstand mit einem Fokus auf Verhaltens- und Bildgebungsstudien über verschiedene Prozesse der sozialen Kognition bei diesen beiden Störungsbildern.


Social cognition in autism spectrum disorder and conduct disorder

Social cognition comprises different aspects of implicit and explicit information processing which take place during social interaction, e. g., implicit attention on social stimuli, emotion recognition, or theory of mind. Deficits in social cognition are associated with disorders that contain symptoms of social interaction deficits, including autism spectrum disorder (ASD) and conduct disorder (CD). This review gives an overview of the current literature on different aspects of social cognition in ASD and CD focusing on behavioral and fMRI studies.

Literatur

  • Adolphs, R. (2003). Cognitive neuroscience: Cognitive neuroscience of human social behaviour. Nature Reviews Neuroscience, 4, 165 – 178. First citation in articleCrossrefGoogle Scholar

  • Akechi, H. , Senju, A. , Kikuchi, Y. , Tojo, Y. , Osanai, H. & Hasegawa, T. (2009). Does gaze direction modulate facial expression processing in children with autism spectrum disorder? Child Development, 80, 1134 – 1146. First citation in articleCrossrefGoogle Scholar

  • Allison, T. , Puce, A. , McCarthy, G. (2000). Social perception from visual cues: Role of the STS region. Trends in Cognitive Sciences, 4, 267 – 278. First citation in articleCrossrefGoogle Scholar

  • American Psychiatric Association. (2000). Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) (4th ed.). Washington, D. C.: American Psychiatric Press. First citation in articleGoogle Scholar

  • Baron-Cohen, S. , Wheelwright, S. , Hill, J. , Raste, Y. , Plumb, I. (2001). The „Reading the Mind in the Eyes” test revised version: A study with normal adults, and adults with Asperger syndrome or high functioning autism. Journal of Child Psychology and Psychiatry, 42, 241 – 251. First citation in articleCrossrefGoogle Scholar

  • Bernhardt, B. C. , Singer, T. (2012). The neural basis of empathy. Annual Review of Neuroscience, 35, 1 – 23. First citation in articleCrossrefGoogle Scholar

  • Blakemore, S. J. , Ouden, H. den , Choudhury, S. , Frith, C. (2007). Adolescent development of the neural circuitry for thinking about intentions. Social Cognitive and Affective Neuroscience, 2, 130 – 139. First citation in articleCrossrefGoogle Scholar

  • Bons, D. , Broek, E. , Scheepers, F. , Herpers, P. , Rommelse, N. , Buitelaaar, J. K. (2012). Motor, emotional, and cognitive empathy in children and adolescents with autism spectrum disorder and conduct disorder. Journal of Abnormal Child Psychology, 41, 425 – 443. First citation in articleCrossrefGoogle Scholar

  • Bosacki, S. L. , Astington, J. W. (1999). Theory of Mind in preadolescence: Relations between social understanding and social competence. Social Development, 8, 237 – 255. First citation in articleCrossrefGoogle Scholar

  • Bowen, E. , Dixon, L. (2010). Concurrent and prospective associations between facial affect recognition accuracy and childhood antisocial behavior. Aggressive Behavior, 36, 305 – 314. First citation in articleGoogle Scholar

  • Burnett, S. , Blakemore, S.-J. (2009). Functional connectivity during a social emotion task in adolescents and in adults. European Journal of Neuroscience, 29, 1294 – 1301. First citation in articleCrossrefGoogle Scholar

  • Castelli, F. , Frith, C. , Happé, F. , Frith, U. (2002). Autism, Asperger syndrome and brain mechanisms for the attribution of mental states to animated shapes. Brain, 125, 1839 – 1849. First citation in articleCrossrefGoogle Scholar

  • Ciaramidaro, A. , Adenzato, M. , Enrici, I. , Erk, S. , Pia, L. , Bara, B. G. , Walter, H. (2007). The intentional network: How the brain reads varieties of intentions. Neuropsychologia, 45, 3105 – 3113. First citation in articleCrossrefGoogle Scholar

  • Ciaramidaro, A. , Becchio, C. , Colle, L. , Bara, B. G. & Walter, H. (2013). Do you mean me? Communicative intentions recruit the mirror and the mentalizing system. Social Cognitive and Affective Neuroscience. doi:10.1093/scan/nst062. First citation in articleGoogle Scholar

  • Crick, N. R. , Dodge, K. A. (1994). A review and reformulation of social information-processing mechanisms in children’s social adjustment. Psychological Bulletin, 115, 74 – 101 First citation in articleCrossrefGoogle Scholar

  • Critchley, H. D. , Daly, E. M. , Bullmore, E. T. , Williams, S. C. , Van Amelsvoort, T. , Robertson, D. M. et al. (2000). The functional neuroanatomy of social behaviour changes in cerebral blood flow when people with autistic disorder process facial expressions. Brain, 123, 2203 – 2212. First citation in articleCrossrefGoogle Scholar

  • Dadds, M. R. (2006). Attention to the eyes and fear-recognition deficits in child psychopathy. The British Journal of Psychiatry, 189, 280 – 281. First citation in articleCrossrefGoogle Scholar

  • Dadds, M. R. , Allen, J. L. , Oliver, B. R. , Faulkner, N. , Legge, K. , Moul, C. et al. (2012). Love, eye contact and the developmental origins of empathy v. psychopathy. The British Journal of Psychiatry, 200, 191 – 196. First citation in articleCrossrefGoogle Scholar

  • Dalton, K. M. , Nacewicz, B. M. , Johnstone, T. , Schaefer, H. S. , Gernsbacher, M. A. , Goldsmith, H. H. et al. (2005). Gaze fixation and the neural circuitry of face processing in autism. Nature Neuroscience, 8, 519 – 26. First citation in articleCrossrefGoogle Scholar

  • Davis, M. , Whalen, P. J. (2001). The amygdala: Vigilance and emotion. Molecular Psychiatry, 6, 13 – 34. First citation in articleCrossrefGoogle Scholar

  • de Wied, M. , Boxtel, A. V. , Posthumus, J. A. , Goudena, P. P. , Matthys, W. (2009). Facial EMG and heart rate responses to emotion-inducing film clips in boys with disruptive behavior disorders. Psychophysiology, 46, 996–1004. First citation in articleCrossrefGoogle Scholar

  • de Wied, M. , van Boxtel, A. , Zaalberg, R. , Goudena, P. & Matthys, W. (2006). Facial EMG responses to dynamic emotional facial expressions in boys with disruptive behavior disorders. Journal of Psychiatric Research, 40, 112–121. First citation in articleCrossrefGoogle Scholar

  • Donno, R. , Parker, G. , Gilmour, J. & Skuse, D. H. (2010). Social communication deficits in disruptive primary-school children. The British Journal of Psychiatry, 196, 282 – 289. First citation in articleCrossrefGoogle Scholar

  • Dziobek, I. , Bahnemann, M. , Convit, A. , Heekeren, H. R. (2010). The role of the fusiform-amygdala system in the pathophysiology of autism. Archives of General Psychiatry, 67, 397 – 405. First citation in articleCrossrefGoogle Scholar

  • Eisenbarth, H. , Alpers, G. W. (2011). Happy mouth and sad eyes: Scanning emotional facial expressions. Emotion, 11, 860 – 865. First citation in articleCrossrefGoogle Scholar

  • Fairchild, G. , Stobbe, Y. , van Goozen, S. H. M. , Calder, A. J. , Goodyer, I. M. (2010). Facial expression recognition, fear conditioning, and startle modulation in female subjects with conduct disorder. Biological Psychiatry, 68, 272 – 279. First citation in articleCrossrefGoogle Scholar

  • Fenning, R. M. , Baker, B. L. , Juvonen, J. (2011). Emotion discourse, social cognition, and social skills in children with and without developmental delays. Child Development, 82, 717 – 731. First citation in articleCrossrefGoogle Scholar

  • Fett, A.-K. J. , Viechtbauer, W. , Dominguez, M.-D.-G. , Penn, D. L. , van Os, J. , Krabbendam, L. (2011). Neuroscience and biobehavioral reviews. Neuroscience and Biobehavioral Reviews, 35, 573 – 588. First citation in articleCrossrefGoogle Scholar

  • Frith, C. D. , Frith, U. (2007). Social cognition in humans. Current Biology, 17, R724–R732. First citation in articleCrossrefGoogle Scholar

  • Gallagher, H. L. , Frith, C. D. (2003). Functional imaging of „theory of mind”. Trends in Cognitive Sciences, 7, 77 – 83. First citation in articleCrossrefGoogle Scholar

  • Gallese, V. , Kesysers, C. , Rizzolatti, G. (2004). A unifying view of the basis of social cognition. Trends in Cognitive Sciences, 8, 396 – 403. First citation in articleCrossrefGoogle Scholar

  • Greene, D. J. , Colich, N. , Iacoboni, M. , Zaidel, E. , Bookheimer, S. Y. , Dapretto, M. R. (2011). Atypical neural networks for social orienting in autism spectrum disorders. NeuroImage, 56, 354 – 362. First citation in articleCrossrefGoogle Scholar

  • Guyer, A. E. , Monk, C. S. , McClure-Tone, E. B. , Nelson, E. E. , Roberson-Nay, R. , Adler, A. D. et al. (2008). A developmental examination of amygdala response to facial expressions. Journal of Cognitive Neuroscience, 20, 1565 – 1582. First citation in articleCrossrefGoogle Scholar

  • Habel, U. , Windischberger, C. , Derntl, B. , Robinson, S. , Kryspin-Exner, I. , Gur, R. C. , Moser, E. (2007). Amygdala activation and facial expressions: Explicit emotion discrimination versus implicit emotion processing. Neuropsychologia, 45, 2369 – 2377. First citation in articleCrossrefGoogle Scholar

  • Hagen, E. A. von dem , Stoyanova, R. S. , Rowe, J. B. , Baron-Cohen, S. , Calder, A. J. (2013). Direct Gaze Elicits Atypical Activation of the Theory-of-Mind Network in Autism Spectrum Conditions. Cerebral Cortex, doi:10.1093/cercor/bht003. First citation in articleGoogle Scholar

  • Han, T. , Alders, G. L. , Greening, S. G. , Neufeld, R. W. J. , Mitchell, D. G. V. (2012). Do fearful eyes activate empathy-related brain regions in individuals with callous traits? Social Cognitive and Affective Neuroscience, 7, 958 – 968. First citation in articleCrossrefGoogle Scholar

  • Hariri, A. R. , Mattay, V. S. , Tessitore, A. , Fera, F. , Weinberger, D. R. (2003). Neocortical modulation of the amygdala response to fearful stimuli. Biological Psychiatry, 53, 494 – 501. First citation in articleCrossrefGoogle Scholar

  • Harms, M. B. , Martin, A. , Wallace, G. L. (2010). Facial emotion recognition in autism spectrum disorders: A review of behavioral and neuroimaging studies. Neuropsychology Review, 20, 290 – 322. First citation in articleCrossrefGoogle Scholar

  • Hooker, C. I. , Paller, K. A. , Gitelman, D. R. , Parrish, T. B. , Mesulam, M. , Reber, P. J. (2003). Brain networks for analyzing eye gaze. Cognitive Brain Research, 17, 406 – 418. First citation in articleCrossrefGoogle Scholar

  • Im-Bolter, N. , Cohen, N. J. , Farnia, F. (2013). I thought we were good: Social cognition, figurative language, and adolescent psychopathology. Journal of Child Psychology and Psychiatry, 54, 724 – 732. First citation in articleCrossrefGoogle Scholar

  • Jones, A. P. , Happé, F. G. E. , Gilbert, F. , Burnett, S. , Viding, E. (2010). Feeling, caring, knowing: Different types of empathy deficit in boys with psychopathic tendencies and autism spectrum disorder. Journal of Child Psychology and Psychiatry, 51, 1188 – 1197. First citation in articleCrossrefGoogle Scholar

  • Jones, A. , Laurens, K. , Herba, C. , Barker, G. & Viding, E. (2009). Amygdala hypoactivity to fearful faces in boys with conduct problems and callous-unemotional traits. American Journal of Psychiatry, 166, 95 – 102. First citation in articleCrossrefGoogle Scholar

  • Kana, R. K. , Libero, L. E. , Hu, C. P. , Deshpande, H. D. , Colburn, J. S. (2012). Functional brain networks and white matter underlying Theory-of-Mind in autism. Social Cognitive and Affective Neuroscience. doi:10.1093/scan/nss106. First citation in articleGoogle Scholar

  • Karatekin, C. (2007). Eye tracking studies of normative and atypical development. Developmental Review, 27, 283 – 348. First citation in articleCrossrefGoogle Scholar

  • Kleinhans, N. M. , Richards, T. , Johnson, L. C. , Weaver, K. E. , Greenson, J. , Dawson, G. , Aylward, E. (2011). fMRI evidence of neural abnormalities in the subcortical face processing system in ASD. NeuroImage, 54, 697 – 704. First citation in articleCrossrefGoogle Scholar

  • Kliemann, D. , Dziobek, I. , Hatri, A. , Baudewig, J. , Heekeren, H. R. (2012). The role of the amygdala in atypical gaze on emotional faces in autism spectrum disorders. Journal of Neuroscience, 32, 9469 – 9476. First citation in articleCrossrefGoogle Scholar

  • Lee, T.-W. , Josephs, O. , Dolan, R. J. , Critchley, H. D. (2006). Imitating expressions: Emotion-specific neural substrates in facial mimicry. Social Cognitive and Affective Neuroscience, 1, 122 – 135. First citation in articleCrossrefGoogle Scholar

  • Likowski, K. U. , Mühlberger, A. , Gerdes, A. B. , Wieser, M. J. , Pauli, P. , Weyers, P. (2012). Facial mimicry and the mirror neuron system: Simultaneous acquisition of facial electromyography and functional magnetic resonance imaging. Frontiers in Human Neuroscience, 6, 214. First citation in articleCrossrefGoogle Scholar

  • Lombardo, M. V. , Chakrabarti, B. , Bullmore, E. T. , Baron-Cohen, S. , Consortium, M. A. (2011). Specialization of right temporo-parietal junction for mentalizing and its relation to social impairments in autism. NeuroImage, 56, 1832 – 1838. First citation in articleCrossrefGoogle Scholar

  • Marsh, A. A. , Blair, R. J. R. (2008). Deficits in facial affect recognition among antisocial populations: A meta-analysis. Neuroscience and Biobehavioral Reviews, 32, 454 – 465. First citation in articleCrossrefGoogle Scholar

  • Marsh, L. E. , Hamilton, A. F. (2011). Dissociation of mirroring and mentalising systems in autism. NeuroImage, 56, 1511 – 1519. First citation in articleCrossrefGoogle Scholar

  • McIntosh, D. N. , Reichmann Decker, A. , Winkielman, P. , Wilbarger, J. L. (2006). When the social mirror breaks: deficits in automatic, but not voluntary, mimicry of emotional facial expressions in autism. Developmental Science, 9, 295 – 302. First citation in articleCrossrefGoogle Scholar

  • Monk, C. S. , McClure, E. B. , Nelson, E. E. , Zarahn, E. , Bilder, R. M. , Leibenluft, E. et al. (2003). Adolescent immaturity in attention-related brain engagement to emotional facial expressions. NeuroImage, 20, 420 – 428. First citation in articleCrossrefGoogle Scholar

  • Mosconi, M. W. , Mack, P. B. , McCarthy, G. , Pelphrey, K. A. (2005). Taking an „intentional stance” on eye-gaze shifts: A functional neuroimaging study of social perception in children. NeuroImage, 27, 247 – 252. First citation in articleCrossrefGoogle Scholar

  • Oberman, L. M. , Winkielman, P. , Ramachandran, V. S. (2009). Slow echo: Facial EMG evidence for the delay of spontaneous, but not voluntary, emotional mimicry in children with autism spectrum disorders. Developmental Science, 12, 510 – 520. First citation in articleCrossrefGoogle Scholar

  • Ochsner, K. , Gross, J. (2005). The cognitive control of emotion. Trends in Cognitive Sciences, 9, 242 – 249. First citation in articleCrossrefGoogle Scholar

  • Oliver, B. R. , Barker, E. D. , Mandy, W. P. L. , Skuse, D. H. , Maughan, B. (2011). Social cognition and conduct problems: A developmental approach. Journal of the American Academy of Child and Adolescent Psychiatry, 50, 385 – 394. First citation in articleCrossrefGoogle Scholar

  • Olsson, A. , Ochsner, K. N. (2007). The role of social cognition in emotion. Trends in Cognitive Sciences, 12, 65 – 71. First citation in articleCrossrefGoogle Scholar

  • Pajer, K. , Leininger, L. , Gardner, W. (2010). Recognition of facial affect in girls with conduct disorder. Psychiatry Research, 175, 244 – 251. First citation in articleCrossrefGoogle Scholar

  • Pelphrey, K. A. , Morris, J. P. , McCarthy, G. , LaBar, K. S. (2007). Perception of dynamic changes in facial affect and identity in autism. Social Cognitive and Affective Neuroscience, 2, 140 – 149. First citation in articleCrossrefGoogle Scholar

  • Pelphrey, K. A. , Singerman, J. D. , Allison, T. & McCarthy, G. (2003). Brain activation evoked by perception of gaze shifts: The influence of context. Neuropsychologia, 41, 156 – 170. First citation in articleCrossrefGoogle Scholar

  • Phillips, M. L. , Drevets, W. C. , Rauch, S. L. , Lane, R. (2003). Neurobiology of emotion perception I: the neural basis of normal emotion perception. Biological Psychiatry, 54, 504 – 514. First citation in articleCrossrefGoogle Scholar

  • Ponari, M. , Conson, M. , D’Amico, N. P. , Grossi, D. , Trojano, L. (2012). Mapping correspondence between facial mimicry and emotion recognition in healthy subjects. Emotion, 12, 1398 – 1403. First citation in articleCrossrefGoogle Scholar

  • Sato, W. , Fujimura, T. , Kochiyama, T. , Suzuki, N. (2013). Relationships among facial mimicry, emotional experience, and emotion recognition. PLoS ONE, 8, e57889. First citation in articleCrossrefGoogle Scholar

  • Sato, W. , Toichi, M. , Uono, S. , Kochiyama, T. (2012). Impaired social brain network for processing dynamic facial expressions in autism spectrum disorders. BMC Neuroscience, 13, 99. First citation in articleCrossrefGoogle Scholar

  • Saxe, R. , Carey, S. , Kanwisher, N. (2004). Understanding other minds: Linking developmental psychology and functional neuroimaging. Annual Review of Psychology, 55, 87 – 124. First citation in articleCrossrefGoogle Scholar

  • Schnell, K. , Bluschke, S. , Konradt, B. , Walter, H. (2011). Functional relations of empathy and mentalizing: An fMRI study on the neural basis of cognitive empathy. NeuroImage, 54, 1743 – 1754. First citation in articleCrossrefGoogle Scholar

  • Schwenck, C. , Gensthaler, A. , Romanos, M. , Freitag, C. M. , Schneider, W. , Taurines, R. (2013). Emotion recognition in girls with conduct problems. European Child and Adolescent Psychiatry. doi:10.1007/s00787 – 013 – 0416 – 8. First citation in articleGoogle Scholar

  • Schwenck, C. , Mergenthaler, J. , Keller, K. , Salehi, S. , Taurines, R. , Romanos, M. et al. (2012). Empathy in children with autism and conduct disorder: group‐specific profiles and developmental aspects. Journal of Child Psychology and Psychiatry, 53, 651 – 659. First citation in articleCrossrefGoogle Scholar

  • Sebastian, C. L. , Fontaine, N. M. G. , Bird, G. , Blakemore, S. J. , De Brito, S. A. , McCrory, E. J. P. , Viding, E. (2012). Neural processing associated with cognitive and affective Theory of Mind in adolescents and adults. Social Cognitive and Affective Neuroscience, 7, 53 – 63. First citation in articleCrossrefGoogle Scholar

  • Senju, A. (2013). Atypical development of spontaneous social cognition in autism spectrum disorders. Brain and Development, 35, 96 – 101. First citation in articleCrossrefGoogle Scholar

  • Sterzer, P. , Stadler, C. , Krebs, A. , Kleinschmidt, A. , Poustka, F. (2005). Abnormal neural responses to emotional visual stimuli in adolescents with conduct disorder. Biological Psychiatry, 57, 7 – 15. First citation in articleCrossrefGoogle Scholar

  • Straube, T. , Pohlack, S. , Mentzel, H. J. , Miltner, W. H. R. (2008). Differential amygdala activation to negative and positive emotional pictures during an indirect task. Behavioural Brain Research, 191, 285 – 288. First citation in articleCrossrefGoogle Scholar

  • Taurines, R. , Schwenck, C. , Westerwald, E. , Sachse, M. , Siniatchkin, M. , Freitag, C. (2012). ADHD and autism: Differential diagnosis or overlapping traits? A selective review. ADHD Attention Deficit and Hyperactivity Disorders, 4, 115 – 139. First citation in articleCrossrefGoogle Scholar

  • Todorov, A. , Engell, A. D. (2008). The role of the amygdala in implicit evaluation of emotionally neutral faces. Social Cognitive and Affective Neuroscience, 3, 303 – 312. First citation in articleCrossrefGoogle Scholar

  • Tottenham, N. , Hertzig, M. E. , Gillespie-Lynch, K. , Gilhooly, T. , Millner, A. J. & Casey, B. J. (2013). Elevated amygdala response to faces and gaze aversion in autism spectrum disorder. Social Cognitive and Affective Neuroscience. doi:10.1093/scan/nst050. First citation in articleGoogle Scholar

  • Uljarevic, M. , Hamilton, A. (2013). Recognition of emotions in autism: A formal meta-analysis. Journal of Autism and Developmental Disorders, 43, 1517 – 1526. First citation in articleCrossrefGoogle Scholar

  • Viding, E. , Sebastian, C. L. , Dadds, M. R. , Lockwood, P. L. , Cecil, C. A. , De Brito, S. A. , McCrory, E. J. (2012). Amygdala response to preattentive masked fear in children with conduct problems: The role of callous-unemotional traits. American Journal of Psychiatry, 169, 1109 – 1116. First citation in articleCrossrefGoogle Scholar

  • Walter, H. , Adenzato, M. , Ciaramidaro, A. , Enrici, I. , Pia, L. , Bara, B. G. (2004). Understanding intentions in social interaction: the role of the anterior paracingulate cortex. Journal of Cognitive Neuroscience, 16, 1854 – 1863. First citation in articleCrossrefGoogle Scholar

  • Walter, H. , Kalckreuth, A. von , Schardt, D. , Stephan, A. , Goschke, T. & Erk, S. (2009). The temporal dynamics of voluntary emotion regulation. PLoS ONE, 4, e6726. First citation in articleCrossrefGoogle Scholar

  • Wang, Y. , Ramsey, R. , de C Hamilton, A. F. (2011). The control of mimicry by eye contact is mediated by medial prefrontal cortex. Journal of Neuroscience, 31, 12001 – 12010. First citation in articleCrossrefGoogle Scholar

  • Woodworth, M. , Waschbusch, D. (2008). Emotional processing in children with conduct problems and callous/unemotional traits. Child: Care, Health and Development, 34, 234 – 244. First citation in articleCrossrefGoogle Scholar

  • Zilbovicius, M. , Meresse, I. , Chabane, N. , Brunelle, F. , Samson, Y. , Boddaert, N. (2006). Autism, the superior temporal sulcus and social perception. Trends in Neurosciences, 29, 359 – 366. First citation in articleCrossrefGoogle Scholar