Whole blood pharmacokinetics of intratumourally injected naked plasmid DNA coding for equine Interleukin 12 (IL-12) was assessed as a means of in vivo gene transfer in the treatment of melanoma in grey horses. The expression of induced interferon gamma (...
Cutaneous melanoma incidence has been increasing during the last few years, and diet has been suggested as one of the lifestyle factors responsible for this increase. Since antioxidant nutrients such as ascorbic acid might prevent skin carcinogenesis, we ...
In the last years a number of new non invasive techniques for the early diagnosis of melanoma have become very popular. In addition to dermoscopy, total body photography and digital dermoscopy frequently assist the dermatologist in differentiating nevi ...
Progress in molecular biology has facilitated a new classification for melanoma. Melanomas today are considered as a heterogeneous group of tumors. The different subtypes are characterized by specific genetic alterations, including mutations in kinase, ...
Until two years ago, there was no systemic therapy that prolonged overall survival in patients with malignant melanoma. In the meantime, two new therapeutic approaches have improved the prognosis of this disease. Ipilimumab is an activator of cytotoxic T-...
Abstract. Melanoma is the most aggressive skin cancer, and surgery is the standard of care for localised disease. However, a risk of local and distant relapse exists despite tumour removal, particularly with thick or ...
Health behaviors of skin cancer patients in melanoma follow-up careAbstract. Malignant melanoma is the most common type of cancer in middle-aged adults. This skin cancer is known to have a particularly high rate of cure during the early stages of the ...