Co-prevalence of arterial aneurysm location – a correlation analysis based on a retrospective cross-sectional observational study
Abstract
Summary:Background: The aim of this retrospective single-centre cross-sectional observational study was to investigate co-prevalence of arterial aneurysm location systematically. Patients and methods: Patients with the diagnosis of any arterial aneurysm from January 2006 to January 2016 were investigated in a single centre. Patients with hereditary disorders of connective tissue, systemic inflammatory disease, or arterial pathologies other than true aneurysms were excluded. Aneurysm locations were assessed for every patient included. For patients with at least two co-existing aneurysms, co-prevalence of aneurysm location was investigated by calculating correlation coefficients and applying Fisher’s exact test. This study report is prepared according to the STROBE statement. Results: Of 3107 identified patients with arterial aneurysms, 918 were excluded. Of the remaining 2189 patients, 951 patients with at least two aneurysms were included in the study. Bilateral aneurysm combinations of paired iliac, femoral and popliteal arteries showed the highest correlation (ϕ=0.35 to 0.67), followed by bilateral combinations of subclavian (ϕ=0.36) and internal carotid (ϕ=0.38) arteries. Abdominal aortic aneurysms in combination with visceral artery aneurysms (ϕ=−0.24 to −0.12), popliteal arteries (ϕ=−0.22) and the ascending aorta (ϕ=−0.19) showed the lowest correlation, followed by the descending aorta in combination with the common iliac arteries (ϕ=−0.12 to −0.13). Conclusions: In our study sample, aneurysm co-prevalence was highly non-random. This should be considered in the context of aneurysm screening programs.
References
1 Editor’s Choice – European Society for Vascular Surgery (ESVS) 2019 Clinical Practice Guidelines on the Management of Abdominal Aorto-iliac Artery Aneurysms. Eur J Vasc Endovasc Surg. 2019;57(1):8–93.
2 . Low prevalence of abdominal aortic aneurysm among 65-year-old Swedish men indicates a change in the epidemiology of the disease. Circulation. 2011;124(10):1118–23.
3 . Impact of the first 5 years of a national abdominal aortic aneurysm screening programme. Br J Surg. 2016;103(9):1125–31.
4 . Baseline prevalence of abdominal aortic aneurysm, peripheral arterial disease and hypertension in men aged 65–74 years from a population screening study (VIVA trial). Br J Surg. 2015;102(8):902–6.
5 Analysis of risk factors for abdominal aortic aneurysm in a cohort of more than 3 million individuals. J Vasc Surg. 2010;52(3):539–48.
6 . A meta-analysis of 50 years of ruptured abdominal aortic aneurysm repair. Br J Surg. 2002;89(6):714–30.
7 . Meta analysis on mortality of ruptured abdominal aortic aneurysms. Eur J Vasc Endovasc Surg. 2008;35(5):558–70.
8 . Inflammasomes in the pathophysiology of aortic disease. Cells. 2021;10(9):2433.
9 Systematic review of the co-prevalence of arterial aneurysms within the vasculature. Eur J Vasc Endovasc Surg. 2021;61(3):473–83.
10 . Screening and management of asymptomatic popliteal aneurysms. J Med Screen. 2002;9(2):92–3.
11 . Incidence of femoral and popliteal artery aneurysms in patients with abdominal aortic aneurysms. J Vasc Surg. 2000;31(5):863–9.
12 . Popliteal aneurysms are common among men with screening detected abdominal aortic aneurysms, and prevalence correlates with the diameters of the common iliac arteries. Eur J Vasc Endovasc Surg. 2020;59(1):67–72.
13 The Society for Vascular Surgery clinical practice guidelines on the management of visceral aneurysms. J Vasc Surg. 2020;72(1s):3s–39s.
14 Editor’s Choice – Management of Descending Thoracic Aorta Diseases: Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS). Eur J Vasc Endovasc Surg. 2017;53(1):4–52.
15 The Society for Vascular Surgery clinical practice guidelines on popliteal artery aneurysms. J Vasc Surg. 2022;75(1s):109s–20s.
16 Pelvic artery aneurysm screening provides value in patients with thoracic aortic aneurysms. Int J Cardiovasc Imaging. 2017;33(10):1627–35.
17 Multiple arterial dissections and connective tissue abnormalities. J Clin Med. 2022;11(12):3264.