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Einfluss von multimodaler sportlicher Aktivität auf Kognition und Alltagskompetenzen bei früher Alzheimer-Demenz (SPORT&KOG)

Published Online:December 08, 2008https://doi.org/10.1024/1011-6877.21.3.163

Abstract

Der vorliegende Bericht beschreibt ein vom Bundesministerium für Gesundheit gefördertes Vorhaben zum «Leuchtturmprojekt Demenz» im Themenfeld 1 «Therapie und Pflegemaßnahmen: Wirksamkeit unter Alltagsbedingungen». Hierbei handelt es sich um eine multizentrische randomisierte Interventionsstudie, die den Einfluss von Sport (multimodale sportliche Aktivität) unter kontrollierten Bedingungen auf die kognitive Entwicklung von Alzheimer-Patienten im frühen Stadium prüft. In einem zweiarmigen Design werden je 150 Patienten mit früher AD unter Verum- bzw. Kontroll-Bedingungen untersucht. Die Verum-Gruppe erhält ein spezifisches sportliches Trainingsprogramm. In der Kontrollgruppe werden lediglich Dehnungsübungen durchgeführt. Primäre Endpunkte der Studie sind die kognitive Leistung der Patienten sowie deren Alltagskompetenz im Verlauf. Die gesundheitsbezogene Lebensqualität der Patienten sowie etwaige Verhaltensstörungen und depressive Symptome werden als sekundäre Endpunkte erfasst. Darüber hinaus werden die Angehörigen zur krankheitsbezogenen Belastung befragt und auf depressive Symptome untersucht. Angelehnt an die Hypothesen der «Initiative Demenzversorgung in der Allgemeinmedizin» (IDA) sollen entsprechende nicht-medikamentöse Versorgungsangebote dazu beitragen, dass Patienten länger in ihrem gewohnten häuslichen Umfeld leben. Im Sinne der Nachhaltigkeit der zu erwartenden Ergebnisse wird ein «Do it yourself»-Manual erstellt, mit dem das Trainingsprogramm auch ohne professionelle Anleitung, z. B. im Rahmen von Selbsthilfegruppen durchgeführt werden kann. Die weitere Implementierung (z. B. in Internetforen und weiteren Medien) wird durch einen Beirat der lokalen Krankenkassen, Gesundheitsämter und der Deutschen Alzheimer-Gesellschaft unterstützt.


Impact of Multimodal Exercise on Cognition and Daily Activity in Patients Suffering from Early Alzheimer’s Dementia (SPORT&KOG)

The present review describes a project supported by the Bundesministerium für Gesundheit («Leuchtturmprojekt Demenz» im Themenfeld 1 «Therapie und Pflegemaßnahmen: Wirksamkeit unter Alltagsbedingungen.»). This project represents a randomized multi-center intervention study aiming for the evaluation of the impact of sport (multimodal exercise) on cognition and daily activity in patients suffering from early Alzheimer’s dementia. In a 2-armed-design 150 patients per verum- and control group respectively will be examined. The verum group will receive a specific exercise program, whereas the control group will receive only stretching exercises. Primary endpoints of our study are the cognitive capacity as well as the daily activity in the course. Secondary endpoints are behaviour problems as well as depressive symptoms. Furthermore, family members will be investigated regarding care givers burden and depressive symptoms. Based on the hypothesis of the «Initiative Demenzversorgung in der Allgemeinmedizin» (IDA) this form of a drug-independent medical care might contribute to a sustained community dwelling life. To support sustainability of our results, a «do it yourself» manual will be developed to facilitate the execution of the training program without professional supervision, e.g. in support groups. The further implementation via internet and other media will be supported by an advisory board of local health insurances, health authorities and the Deutsche Alzheimer-Gesellschaft (German Alzheimer Society).

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