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Themenschwerpunkt

Was tun, bevor es losgeht? FRITZ – Das Frühinterventions- und Therapiezentrum in Berlin

Published Online:https://doi.org/10.1024/1661-4747/a000309

Zusammenfassung. Psychosen manifestieren sich häufig im jungen Erwachsenenalter und können schwerwiegende Auswirkungen auf das Leben der Betroffenen und ihrer Angehörigen haben. In den meisten Fällen geht der Erstmanifestation eine mehrjährige Prodromalphase mit heterogener Symptomatik und erheblichem Funktionsverlust voraus. Eine Identifikation dieser Personen mit erhöhtem Erkrankungsrisiko ermöglicht es, präventive Maßnahmen zu ergreifen. Eine frühe Diagnosestellung und Einleitung einer adäquaten Behandlung, die pharmakologische, psycho- und soziotherapeutische Ansätze umfasst, sind von hoher Bedeutung für die Prognose der Erkrankung. Am besten können diese Ziele im Rahmen von spezialisierten Behandlungsangeboten für junge, erstmals psychotisch erkrankte Menschen bzw. mit erhöhtem Erkrankungsrisiko erreicht werden. Während solche Zentren in vielen Ländern Teil der Regelversorgung sind, sind sie im deutschsprachigen Raum noch die Ausnahme. Das Frühinterventions- und Therapiezentrum FRITZ am Urban bietet ambulante und stationäre Angebote zur Behandlung von Risikopersonen für die Entwicklung psychotischer Störungen und Patienten in einer frühen Phase der Erkrankung. Durch niedrigschwellige Beratungsangebote, eine zugewandte und unterstützende Haltung des multiprofessionellen Teams, das Angebot stabiler Bezugspersonen, die Wahrung der Patientenautonomie, eine Stärkung des Selbstwertes, sowie den Einbezug von Peers soll ein positiver Erstkontakt mit dem Versorgungssystem ermöglicht werden. Die Behandlung ist intensiv psychotherapeutisch ausgerichtet und soll durch frühen Einsatz von Individual Placement and Support (IPS) Strategien nicht nur zu einer Symptomremission, sondern auch zu einer funktionellen Recovery beitragen.


What to do before it starts? FRITZ – The early intervention and therapy centre in Berlin

Abstract. First episode psychosis frequently manifest in young adulthood and can impact severely on the lives of the affected individuals and their relatives. In most cases, a first episode psychosis is preceded by a long-term prodromal phase with heterogeneous symptomatology and considerable functional impairment. The early identification of individuals at high risk of psychosis enables a timely implementation of preventive strategies, and an early diagnosis and the start of an adequate therapy, including pharmacological, psychotherapeutic and socio-therapeutic approaches, are essential for the prognosis of the disease. These aims are best achieved in specialised early intervention centres for young people experiencing first-episode psychosis. While in many countries such centres form part of standard care provisions, in German-speaking areas they remain the exception. The Early Intervention and Therapy Centre FRITZ am Urban offers in- and out-patient care for persons at risk of psychosis as well as for individuals in an early phase of the disease. Low-threshold counselling, an open and supportive attitude on the part of the multidisciplinary team, the availability of regular contact persons, the preservation of patient autonomy, the strengthening of a patient’s self-esteem and peer consultation and peer support are designed to create a positive first contact experience with the psychiatric care system. The treatment on offer is of a pronounced psychotherapeutic orientation, and an early application of Individual Placement and Support (IPS) strategies not only seeks to reduce symptoms but also to contribute to functional recovery.

Literatur

  • Aghotor, J. , Pfueller, U. , Moritz, S. , Weisbrod, M. & Roesch-Ely, D. (2010). Metacognitive training for patients with schizophrenia (MCT): Feasibility and preliminary evidence for its efficacy. Journal of Behavior Therapy and Experimental Psychiatry , 41 , 207–211. First citation in articleCrossrefGoogle Scholar

  • Bechdolf, A. & Klingberg, S. (2014). Psychotherapie bei schizophrenen Störungen: Kein Evidenz-, sondern ein Implementierungsproblem. Psychiatrische Praxis , 41 , 8–10. First citation in articleCrossrefGoogle Scholar

  • Bechdolf, A. , Veith, V. , Güttgemanns, J. & Gross, S. (2010). Kognitive Verhaltenstherapie bei Personen mit erhöhtem Psychoserisiko: Ein Behandlungsmanual . Bern: Huber. First citation in articleGoogle Scholar

  • Birchwood, M. , Todd, P. & Jackson, C. (1998). Early intervention in psychosis: the critical-period hypothesis. International Clinical Psychopharmacology , 13 , 31–40. First citation in articleCrossrefGoogle Scholar

  • Bond, G. R. , Drake, R. E. & Luciano, A. (2015). Employment and educational outcomes in early intervention programmes for early psychosis: a systematic review. Epidemiology and Psychiatric Sciences , 24 , 446–457. First citation in articleCrossrefGoogle Scholar

  • Boonstra, N. , Klaassen, R. , Sytema, S. , Marshall, M. , De Haan, L. , Wunderink, L. , Wiersma, D. (2012). Duration of untreated psychosis and negative symptoms – A systematic review and meta-analysis of individual patient data. Schizophrenia Research , 142 , 12–19. First citation in articleCrossrefGoogle Scholar

  • Coldham, E. L. , Addington, J. & Addington, D. (2002). Medication adherence of individuals with a first episode of psychosis. Acta Psychiatrica Scandinavica , 106 , 286–290. First citation in articleCrossrefGoogle Scholar

  • Correll, C. U. , Olvet, D. M. , Auther, A. M. , Hauser, M. , Kishimoto, T. , Carrión, R. E. , … Cornblatt, B. A. (2014). The Bipolar Prodrome Symptom Interview and Scale–Prospective (BPSS-P): description and validation in a psychiatric sample and healthy controls. Bipolar disorders , 16 , 505–522. First citation in articleCrossrefGoogle Scholar

  • Cotton, S. M. , Filia, K. M. , Ratheesh, A. , Pennell, K. , Goldstone, S. & McGorry, P. D. (2015). Early psychosis research at Orygen, The National Centre of Excellence in Youth Mental Health. Social Psychiatry and Psychiatric Epidemiology , 51 , 1–13. First citation in articleCrossrefGoogle Scholar

  • Fusar-Poli, P. , Deste, G. , Smieskova, R. , Barlati, S. , Yung, A. R. , Howes, O. , … Borgwardt, S. (2012). Cognitive Functioning in prodromal psychosis: A Meta-analysis. Archives of General Psychiatry , 69 , 562–571. First citation in articleCrossrefGoogle Scholar

  • Fusar-Poli, P. , Rocchetti, M. , Sardella, A. , Avila, A. , Brandizzi, M. , Caverzasi, E. , … McGuire, P. (2015). Disorder, not just state of risk: meta-analysis of functioning and quality of life in people at high risk of psychosis. The British Journal of Psychiatry , 207 , 198–206. First citation in articleCrossrefGoogle Scholar

  • van der Gaag, M. , Smit, F. , Bechdolf, A. , French, P. , Linszen, D. H. , Yung, A. R. , … Cuijpers, P. (2013). Preventing a first episode of psychosis: Meta-analysis of randomized controlled prevention trials of 12month and longer-term follow-ups. Schizophrenia Research , 149 , 56–62. First citation in articleCrossrefGoogle Scholar

  • Häfner, H. , Maurer, K. , Löffler, W. , an der Heiden, W. , Hambrecht, M. & Schultze-Lutter, F. (2003). Modeling the early course of schizophrenia. Schizophrenia Bulletin , 29 , 325–340. First citation in articleCrossrefGoogle Scholar

  • Hoffmann, H. , Jäckel, D. , Glauser, S. , Mueser, K. T. & Kupper, Z. (2014). Long-term effectiveness of supported employment: 5-Year follow-up of a randomized controlled trial. American Journal of Psychiatry , 171 , 1183–1190. First citation in articleCrossrefGoogle Scholar

  • Jacobi, F. , Höfler, M. , Siegert, J. , Mack, S. , Gerschler, A. , Scholl, L. , … Wittchen, H.-U. (2014). Twelve-month prevalence, comorbidity and correlates of mental disorders in Germany: the Mental Health Module of the German Health Interview and Examination Survey for Adults (DEGS1-MH). International journal of methods in psychiatric research , 23 , 304–319. First citation in articleCrossrefGoogle Scholar

  • Karow, A. , Bock, T. , Naber, D. , Löwe, B. , Schulte-Markwort, M. , Schäfer, I. , … Lambert, M. (2013). Die psychische Gesundheit von Kindern, Jugendlichen und jungen Erwachsenen – Teil 2: Krankheitslast, Defizite des deutschen Versorgungssystems, Effektivität und Effizienz von „Early Intervention Services“. Fortschritte der Neurologie Psychiatrie , 81 , 628–638. First citation in articleCrossrefGoogle Scholar

  • Laier, S. , Biester, A. & Bechdolf, A. (2014). Psychotherapie bei schizophrenen Erkrankungen. Nervenheilkunde , 33 , 693–697. First citation in articleCrossrefGoogle Scholar

  • Large, M. M. & Nielssen, O. (2011). Violence in first-episode psychosis: A systematic review and meta-analysis. Schizophrenia Research , 125 , 209–220. First citation in articleCrossrefGoogle Scholar

  • Leopold, K. , Nikolaides, A. , Bauer, M. , Bechdolf, A. , Correll, C. U. , Jessen, F. , … Pfennig, A. (2015). Angebote zur Früherkennung von Psychosen und bipolaren Störungen in Deutschland: Bestandsaufnahme. Der Nervenarzt , 86 , 352–358. First citation in articleCrossrefGoogle Scholar

  • Leopold, K. , Pfeiffer, S. , Correll, C. U. , Bauer, M. & Pfennig, A. (2013). Früherkennungszentren für psychische Erkrankungen – ein Komplementärangebot der psychiatrischen Regelversorgung in Deutschland. Psychiatrische Praxis , 40 , 264–270. First citation in articleCrossrefGoogle Scholar

  • Leopold, K. , Ritter, P. , Correll, C. U. , Marx, C. , Özgürdal, S. , Juckel, G. , … Pfennig, A. (2012). Risk constellations prior to the development of bipolar disorders: Rationale of a new risk assessment tool. Journal of Affective Disorders , 136 , 1000–1010. First citation in articleCrossrefGoogle Scholar

  • Luciano, A. , Metcalfe, J. D. , Bond, G. R. , Xie, H. , Miller, A. L. , Riley, J. , … Drake, R. E. (2016). Hospitalization risk before and after employment among adults with schizophrenia, bipolar disorder, or major fepression. Psychiatric Services , 67 , 1131–1138. First citation in articleCrossrefGoogle Scholar

  • McCrone, P. , Craig, T. K. J. , Power, P. & Garety, P. A. (2010). Cost-effectiveness of an early intervention service for people with psychosis. The British Journal of Psychiatry , 196 , 377–382. First citation in articleCrossrefGoogle Scholar

  • McGorry, P. D. (2008). Is early intervention in the major psychiatric disorders justified? Yes. British Medical Journal , 337 , a695. First citation in articleCrossrefGoogle Scholar

  • McGorry, P. D. (2015). Early intervention in psychosis: obvious, effective, overdue. The Journal of Nervous and Mental Disease , 203 , 310. First citation in articleCrossrefGoogle Scholar

  • McLean, J. , Biggs, H. , Whitehead, I. , Pratt, R. & Maxwell, M. (2009). Evaluation of the delivering for mental health peer support worker pilot scheme . Edinburgh: Scottish Government Social Research. First citation in articleGoogle Scholar

  • Miller, T. J. , McGlashan, T. H. , Rosen, J. L. , Cadenhead, K. , Ventura, J. , McFarlane, W. , … Woods, S. W. (2003). Prodromal assessment with the structured interview for prodromal syndromes and the scale of prodromal symptoms: predictive validity, interrater reliability, and training to reliability. Schizophrenia Bulletin , 29 , 703–715. First citation in articleCrossrefGoogle Scholar

  • Müller, H. , Laier, S. & Bechdolf, A. (2014). Evidence-based psychotherapy for the prevention and treatment of first-episode psychosis. European Archives of Psychiatry and Clinical Neuroscience , 264 , 17–25. First citation in articleCrossrefGoogle Scholar

  • NICE. (2014, February 12). Psychosis and schizophrenia in adults: prevention and management. Clinical guidline . Online: https://www.nice.org.uk/guidance/cg178/chapter/1-recommendations?unlid=214673181201631735658 [22.06.2016]. First citation in articleGoogle Scholar

  • van Os, J. , Kenis, G. & Rutten, B. P. F. (2010). The environment and schizophrenia. Nature , 468 , 203–212. First citation in articleCrossrefGoogle Scholar

  • Penttilä, M. , Jääskeläinen, E. , Hirvonen, N. , Isohanni, M. & Miettunen, J. (2014). Duration of untreated psychosis as predictor of long-term outcome in schizophrenia: systematic review and meta-analysis. The British Journal of Psychiatry , 205 , 88–94. First citation in articleCrossrefGoogle Scholar

  • Pharoah, F. , Rathbone, J. , Mari, J. & Streiner, D. (2003, July 13). Family intervention for schizophrenia. Cochrane Schizophrenia Group . Chichester, UK: John Wiley & Sons. First citation in articleGoogle Scholar

  • Purcell, R. , Goldstone, S. , Moran, J. , Albiston, D. , Edwards, J. , Pennell, K. & McGorry, P. D. (2011). Toward a twenty-first century approach to youth mental health care: Some Australian initiatives. International Journal of Mental Health , 40 , 72–87. First citation in articleCrossrefGoogle Scholar

  • Ramsay, C. E. , Broussard, B. , Goulding, S. M. , Cristofaro, S. , Hall, D. , Kaslow, N. J. , … Compton, M. T. (2011). Life and treatment goals of individuals hospitalized for first-episode nonaffective psychosis. Psychiatry Research , 189 , 344–348. First citation in articleCrossrefGoogle Scholar

  • Robinson, D. , Woerner, M. G. , Alvir, J. M. J. , Bilder, R. & Goldman, R. (1999). Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder. Archives of General Psychiatry , 56 , 241–247 First citation in articleCrossrefGoogle Scholar

  • Schmidt, S. J. , Schultze-Lutter, F. , Schimmelmann, B. G. , Maric, N. P. , Salokangas, R. K. R. , Riecher-Rössler, A. , … Ruhrmann, S. (2015). EPA guidance on the early intervention in clinical high risk states of psychoses. European Psychiatry , 30 , 388–404. First citation in articleCrossrefGoogle Scholar

  • Schultze-Lutter, F. , Addington, J. , Ruhrmann, S. & Klosterkötter, J. (2007). Schizophrenia proneness instrument, adult version (SPI-A) . Rom: Giovanni Fioriti Editore. First citation in articleGoogle Scholar

  • Schultze-Lutter, F. , Michel, C. , Schmidt, S. J. , Schimmelmann, B. G. , Maric, N. P. , Salokangas, R. K. R. , … Klosterkötter, J. (2015). EPA guidance on the early detection of clinical high risk states of psychoses. European Psychiatry , 30 , 405–416. First citation in articleCrossrefGoogle Scholar

  • Schultze-Lutter, F. , Ruhrmann, S. , Fusar-Poli, P. , Bechdolf, A. , Schimmelmann, B. G. & Klosterkotter, J. (2012). Basic symptoms and the prediction of first-episode psychosis. Current pharmaceutical design , 18 , 351–357. First citation in articleCrossrefGoogle Scholar

  • Senatsverwaltung für Gesundheit und Soziales. (2014). Sozialstrukturatlas Berlin. Online: http://www.gsi-berlin.info/gsi_suchen.asp?seite=2&cbfest=Kategorie,Bereich,Thema,Unterthema&kategorie=Berichte&bereich=GBE&thema=Spezialberichte&unterthema=Sozialstrukturatlas [25.06.2016]. First citation in articleGoogle Scholar

  • Stucki, C. & Grawe, K. (2007). Bedürfnis- und Motivorientierte Beziehungsgestaltung: Hinweise und Handlungsanweisungen für Therapeuten. Psychotherapeut , 52 , 16–23. First citation in articleCrossrefGoogle Scholar

  • Turner, D. T. , van der Gaag, M. , Karyotaki, E. & Cuijpers, P. (2014). Psychological interventions for psychosis: A meta-analysis of comparative outcome studies. American Journal of Psychiatry , 171 , 523–538. First citation in articleCrossrefGoogle Scholar

  • Utschakowski, J. (2012). EX-IN-Ausbildungen: Experienced Involvement – Pro & Kontra. Psychiatrische Praxis , 39 , 202–203. First citation in articleCrossrefGoogle Scholar

  • Whitehorn, D. , Brown, J. , Richard, J. , Rui, Q. & Kopala, L. (2002). Multiple dimensions of recovery in early psychosis. International Review of Psychiatry , 14 , 273–283. First citation in articleCrossrefGoogle Scholar

  • Wojak, M. (2004). Drogenkonsum und Konsummuster in Berlin. SUCHT , 50 , 46–49. First citation in articleLinkGoogle Scholar

  • Yung, A. R. & McGorry, P. D. (1996). The initial prodrome in psychosis: descriptive and qualitative aspects. The Australian and New Zealand Journal of Psychiatry , 30 , 587–599. First citation in articleCrossrefGoogle Scholar