Skip to main content
Grundlagen

Nicht-suizidale Selbstverletzung (NSSV) bei Jugendlichen und jungen Erwachsenen

Published Online:https://doi.org/10.1026/0942-5403/a000065

Nicht-suizidales selbstverletzendes Verhalten (NSSV) stellt ein häufiges Phänomen sowohl im Jugendalter als auch im jungen Erwachsenenalter dar. NSSV zeigt auch in nicht-klinischen Populationen eine enge Beziehung zu psychopathologischen Auffälligkeiten. Im klinischen Kontext steht ein repetitives NSSV häufig im Zusammenhang mit einer Borderline-Persönlichkeitsstörung (BPS) im Jugend- wie auch im Erwachsenenalter. Um die therapeutische Handlungsfähigkeit zu erweitern, ist ein verbessertes Verständnis der Entstehung und Aufrechterhaltung von NSSV dringend erforderlich. In dieser Übersichtsarbeit werden neben der Phänomenologie und den intra- und interpersonellen Funktionen der NSSV und den psychosozialen Risikofaktoren auch Ergebnisse der neurobiologischen Grundlagenforschung zur Pathogenese dieses Phänomens referiert. Im Sinne eines Diathese-Stress-Modells werden die wichtigsten Vulnerabilitätsfaktoren zusammengestellt und zukünftige Forschungsstrategien entworfen.


Non-suicidal self-injury (NSSI) in adolescents and young adults

Non-suicidal self-injurious behavior (NSSI) is a common phenomenon both in adolescence and young adulthood. NSSI in non-clinical populations also shows a close relationship to psychopathological symptoms. In the clinical context, repetitive NSSI is often linked with borderline personality disorder in adolescent as well as in adult patients. To extend the therapeutic options a better understanding of the origin and maintenance of NSSI is urgently needed. In this review, in addition to the phenomenology, intra- and interpersonal functions of NSSI and psychosocial risk factors, the results of neurobiological research on the pathogenesis of this phenomenon is referenced. In terms of a diathesis-stress model, the main vulnerability factors are delineated and future research strategies are outlined.

Literatur

  • Barron, J. , Sandman, C. A. (1983). Relationship of sedative-hypnotic response to self-injurious behavior and stereotypy by mentally retarded clients. American Journal of Mental Deficiency, 8, 177 – 186. First citation in articleGoogle Scholar

  • Barron, J. , Sandman, C. A. (1985). Paradoxical excitement to sedative-hypnotics in mentally retarded clients. American Journal of Mental Deficiency, 90,124 – 129. First citation in articleGoogle Scholar

  • Bohus, M. , Limberger, M. , Ebner, U. , Glocker, F. , Wernz, M. & Lieb, K. (2000). Pain perception during self-reported distress and calmness in patients with borderline personality disorder and self-mutilating behaviour. Psychiatry Research, 9, 251-260. First citation in articleCrossrefGoogle Scholar

  • Brunner, R. , Parzer, P. , Haffner, J. , Stehen, R. , Roos, J. , Klett, M. & Resch, F. (2007). Prevalence and psychological correlates of occasional and repetitive deliberate self-harm in adolescents. Archives of Pediatrics and Adolescent Medicine, 161, 641 – 649. First citation in articleCrossrefGoogle Scholar

  • Chapman, A. L. , Gratz, K. L. , Brown, M. Z. (2006). Solving the puzzle of deliberate self-harm: The experiential avoidance model. Behaviour Research and Therapy, 44, 371 – 394. First citation in articleCrossrefGoogle Scholar

  • Coccaro, E. F. , McCloskey, M. S. , Fitzgerald, D. A. , Phan, K. L. (2007). Amygdala and orbitofrontal reactivity to social threat in individuals with impulsive aggression. Biological Psychiatry, 6, 168 – 178. First citation in articleCrossrefGoogle Scholar

  • Coccaro, E. F. , Siever, L. J. , Klar, H. M. , Maurer, G. , Cochrane, K. , Cooper, T. B. et al. (1989). Serotonergic studies in patients with affective and personality disorders. Correlates with suicidal and impulsive aggressive behavior. Archives of General Psychiatry, 46, 587 – 599. First citation in articleCrossrefGoogle Scholar

  • Favazza, A. R. (1989). Why patients mutilate themselves. Hospital Community Psychiatry, 40, 37 – 145. First citation in articleGoogle Scholar

  • Fleck, M. S. , Daselaar, S. M. , Dobbins, I. G. & Cabeza, R. (2006). Role of prefrontal and anterior cingulate regions in decision-making processes shared by memory and nonmemory tasks. Cerebral Cortex, 16, 1623 – 1630. First citation in articleCrossrefGoogle Scholar

  • Haines, J. , Williams, C.L. , Brain, K. L. & Wilson, G. V. (1995). The psychophysiology of self-mutilation. Journal of Abnormal Psychology, 104, 471 – 489. First citation in articleCrossrefGoogle Scholar

  • Hankin, B. L. , Abela, J. R. Z. (2011). Nonsuicidal self-injury in adolescence: Prospective rates and risk factors in a 2 ½ year longitudinal study. Psychiatry Research, 186, 65 – 70. First citation in articleCrossrefGoogle Scholar

  • Hayes, S. C. , Wilson, K. G. , Gifford, E. V. , Follette, V. M. & Strosahl, K. (1996). Experiental avoidance and behavioral disorders: A functional dimensional approach to diagnosis and treatment. Journal of Consulting and Clinical Psychology, 64, 1152-1168. First citation in articleCrossrefGoogle Scholar

  • Herpertz, S. (1995). Self-injurious behaviour. Psychopathological and nosological characteristics in subtypes of self-injurers. Acta Psychiatrica Scandinavcia, 91, 57 – 68. First citation in articleCrossrefGoogle Scholar

  • Herpertz, S. , Saß, H. (1994). Offene Selbstschädigung. Nervenarzt, 65, 296 – 306. First citation in articleGoogle Scholar

  • Jacobson, C. M. , Gould, M. (2007). The epidemiology and phenomenology of non-suicidal self-injurious behavior among adolescents: A critical review of the literature. Archives of Suicide Research, 11, 129 – 147. First citation in articleCrossrefGoogle Scholar

  • Kaess, M. (2010). Selbstverletzendes Verhalten. Ein zunehmendes Problem bei Jugendlichen. Kinder- und Jugendmedizin, 2, 89 – 93. First citation in articleGoogle Scholar

  • Kaess, M. (2011). Selbstverletzendes Verhalten im Jugendalter. In M. Schulte-Markwort & F. Resch, (Hrsg.), Risiken der Entwicklung im Kindes- und Jugendalter. Weinheim: Beltz. First citation in articleGoogle Scholar

  • Kaess, M. , Hille, M. , Parzer, P. , Maser-Gluth, C. , Resch, F. , Brunner, R. (2011). Neuroendocrinological stress response to acute psychosocial stress in adolescents engaging in nonsuicidal self-injury. Psychoneuroendocrinology, epub ahead of print. First citation in articleGoogle Scholar

  • Kleindienst, N. , Bohus, M. , Ludaescher, P. , Limberger, M. F. , Kuenkele, K. , Ebner-Priemer, U. W. et al. (2008). Motives for non-suicidal self-injury among women with Borderline Personality Disorder. Journal of Nervous and Mental Diseases, 196, 230 – 236. First citation in articleCrossrefGoogle Scholar

  • Kraus, A. , Valerius, G. , Seifritz, E. , Ruf, M. , Bremner, J. D. , Bohus, M. et al. (2010). Scriptdriven imagery of self-injurious behavior in patients with borderline personality disorder: An fMRI study. Acta Psychiatrica Scandinavica, 121, 41 – 51. First citation in articleCrossrefGoogle Scholar

  • Leibenluft, E. , Gardner, D. L. , Cowdry, R. W. (1987). The inner experience of the borderline self-mutilator. Journal of Personality Disorders, 1, 317 – 24. First citation in articleCrossrefGoogle Scholar

  • Linnoila, M. , Virkkunen, M. , Scheinin, M. , Nuutila, A. , Rimon, R. , Goodwin, F. K. (1983). Low cerebrospinal fluid 5-hydroxyindolacetic acid concentration differentiates impulsive from nonimpulsive violent behavior. Life Sciences, 33, 2609 – 2614. First citation in articleCrossrefGoogle Scholar

  • Ludäscher, P. , Greffrath, W. , Schmahl, C. , Kleindienst, N. , Jochims, A. , Baumgärtner, U. et al. (2008). Does discontinuation of self-injury normalise pain perception in patients with borderline personality disorder?–A cross-sectional study. Acta Psychiatrica Scandinavica, 120, 62 – 70. First citation in articleCrossrefGoogle Scholar

  • Muehlenkamp, J. J. , Ertelt, T. W. , Miller, A. L. , Claes, L. (2011). Borderline personality symptoms differentiate non-suicidal and suicidal self-injury in ethnically diverse adolescent outpatients. Journal of Psychological and Psychiatry, 52, 148 – 155. First citation in articleCrossrefGoogle Scholar

  • New, A. S. , Trestman, R .L. , Mitropoulou, V. , Benishay, D. S. , Coccaro, E. , Silverman, J. et al. (1997). Serotonergic function and self-injurious behavior in personality disorder patients. Psychiatry Research, 69, 17 – 26. First citation in articleCrossrefGoogle Scholar

  • Niedtfeld, I. , Schulze, L. , Kirsch, P. , Herpertz, S. C. , Bohus, M. , Schmahl, C. (2010). Affect regulation and pain in borderline personality disorder: A possible link to the understanding of self-injury. Biological Psychiatry, 68, 383 – 391. First citation in articleCrossrefGoogle Scholar

  • Nitkowski, D , Petermann, F. (2009). Verhaltensdiagnostik selbstverletzenden Verhaltens. Nervenheilkunde, 28, 227 – 231. First citation in articleCrossrefGoogle Scholar

  • Nock, M. K. (2009a). Why do people hurt themselves? New insights into the nature and functions of self-injury. Current Directions in Psychological Science, 18, 78 – 83. First citation in articleCrossrefGoogle Scholar

  • Nock, M. K. (Ed.). (2009b). Understanding nonsuicidal self-injury: Origins, assessment, and treatment. Washington: American Psychological Association. First citation in articleCrossrefGoogle Scholar

  • Nock, M.K. (2010). Self injury. Annual Review of Clinical Psychology, 6, 15.1 – 15.25. First citation in articleCrossrefGoogle Scholar

  • Nock, M. K. , Prinstein, M. (2005). Contextual features and behavioral functions of self-mutilation among adolescents. Journal of Abnormal Psychology, 114, 140 – 146. First citation in articleCrossrefGoogle Scholar

  • Ochsner, K. N. , Bunge, S. A. , Gross, J. J. , Gabrieli, J. D. E. (2002). Rethinking feelings: An fMRI study of the cognitive regulation of emotion. Journal of Cognitive Neuroscience, 14, 1215 – 1229. First citation in articleCrossrefGoogle Scholar

  • Petermann, F. , Nitkowski, D. (2008). Selbstverletzendes Verhalten. Erscheinungsformen, Risikofaktoren und Verlauf. Nervenarzt, 79, 1017 – 1022. First citation in articleCrossrefGoogle Scholar

  • Petermann, F. , Nitkowski, D. (2011). Selbstverletzendes Verhalten: Merkmale, Diagnostik und Risikofaktoren. Psychotherapie, Psychosomatik und Medizinische Psychologie, 61, 6 – 15. First citation in articleCrossrefGoogle Scholar

  • Petermann, F. , Winkel, S. (2007). Selbstverletzendes Verhalten bei Kindern mit intellektueller Beeinträchtigung. Monatsschrift Kinderheilkunde, 155, 937 – 944. First citation in articleCrossrefGoogle Scholar

  • Petermann, F. , Winkel, S. (2009). Selbstverletzendes Verhalten (2., veränd. Aufl.). Göttingen: Hogrefe. First citation in articleGoogle Scholar

  • Plener, P. L. , Libal, G. , Keller, F. , Fegert J. M. & Muehlenkamp, J. J. (2009a). An international comparison of adolescent non-suicidal self-injury (NSSI) and suicide attempts: Germany and the USA. Psychological Medicine, 39, 1549 – 1558. First citation in articleCrossrefGoogle Scholar

  • Plener, P. L. , Brunner, R. , Resch, F. , Fegert, J. M. , Libal, G. (2010). Selbstverletzendes Verhalten im Jugendalter. Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, 38, 77 – 89. First citation in articleLinkGoogle Scholar

  • Plener, P. L. , Kapusta, N. D. , Kölch, M. G. , Kaess, M. & Brunner, R. (2011). Nicht-suizidale Selbstverletzung als eigenständige Diagnose. Implikationen des DSM-V Vorschlages für Forschung und Klinik selbstverletzenden Verhaltens bei Jugendlichen. Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie (in revision). First citation in articleGoogle Scholar

  • Prinstein, M .J. , Heibron, N. , Guerry, J. D. , Franklin, J. C. , Rancourt, D. , Simon, V. et al. (2010). Peer influence and non-suicidal self-injury: Longitudinal results in community and clinically-referred adolescent samples. Journal of Abnormal Child Psychology, 38, 669 – 682. First citation in articleCrossrefGoogle Scholar

  • Reitz, S. , Krause-Utz, A. , Pogatzki-Zahn, E. M. , Ebner-Priemer, U. , Bohus, M. , Schmahl, C. (in press). Stress regulation and incision in borderline personality disorder–a pilot study modelling cutting behavior. Journal of Personality Disorders. First citation in articleGoogle Scholar

  • Resch, F. , Karwautz, A. , Schuch, B. , Lang, E. (1993). Kann Selbstverletzung als süchtiges Verhalten bei Jugendlichen angesehen werden? Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, 21, 253 – 259. First citation in articleGoogle Scholar

  • Resch, F. , Parzer, P. , Brunner, R. & the BELLA study group, (2008). Self-mutilation and suicidal behaviour in children and adolescents: prevalence and psychosocial correlates: Results of the BELLA study. European Child and Adolescent Psychiatry (Suppl 1), 17, 92 – 98. First citation in articleCrossrefGoogle Scholar

  • Resch, F. , Parzer, P. , Haffner, J. , Stehen, R. , Roos, J. , Klett, M. et al. (2009). Prävalenz und psychische Auffälligkeiten bei Jugendlichen mit selbstverletzendem Verhalten. In R. Brunner & F. Resch, (Hrsg.), Borderline-Störungen und selbstverletzendes Verhalten bei Jugendlichen (S. 85 – 94). Göttingen: Vandenhoek & Ruprecht. First citation in articleCrossrefGoogle Scholar

  • Russ, M. J. , Roth, S. D. , Lerman, A. , Kakuma, T. , Harrison, K. , Shindledecker, R. D. et al. (1992). Pain perception in self-injurious patients with borderline personality disorder. Biological Psychiatry, 32, 501 – 511. First citation in articleCrossrefGoogle Scholar

  • Russ, M. J. , Roth, S. D. , Kakuma, T. , Harrison, K. , Hull, J. W. (1994). Pain perception in self-injurious borderline patients: Naloxone effects. Biological Psychiatry, 35, 207 – 209. First citation in articleCrossrefGoogle Scholar

  • Sandman, C. A. , Hetrick, W. P. (1995). Opiate mechanisms in self-injury. Mental Retardation in Developmental Disabilities Research Reviews, 1, 130 – 136. First citation in articleCrossrefGoogle Scholar

  • Schmahl, C. G. , Bohus, M. , Esposito, F. , Treede, R. D. , Di Salle, F. , Greffrath, W. et al. (2006). Neural correlates of antinociception in borderline personality disorder. Archive of General Psychiatry, 63, 659 – 667. First citation in articleCrossrefGoogle Scholar

  • Shaffer, D. , Jacobson, C. (2010). Proposal to the DSM-V childhood disorder and mood disorder work groups to include non-suicidal self-injury (NSSI) as a DSM-V Disorder. Washington: American Psychiatric Association. First citation in articleGoogle Scholar

  • Shaw-Welch, S. (2004). Patterns of emotion in response to parasuicide imagery in borderline personality disorder. University of Washington: Dissertation. First citation in articleGoogle Scholar

  • Shearer, S. L. (1994). Phenomenology of self-injury among inpatient women with borderline personality disorder. Journal of Nervous Mental Diseases, 182, 424 – 26. First citation in articleGoogle Scholar

  • Simeon, D. , Stanley, B. , Frances, A. , Mann, J. J. , Winchel, R. , Stanley, M. (1992). Self-mutilation in personality disorders: Psychological and biological correlates. American Journal of Psychiatry, 149, 221 – 226. First citation in articleCrossrefGoogle Scholar

  • Simeon, D. , Hollander, E. (2001). Self-injurious behaviors. Assessment and treatment. Washington: American Psychiatric Publishing. First citation in articleGoogle Scholar

  • Sonne, S. , Rubey, R. , Brady, K. , Malcolm, R. & Morris, T. (1996). Naltrexone treatment of self-injurious thoughts and behaviors. Journal of Nervous Mental Diseases, 184, 192 – 195. First citation in articleCrossrefGoogle Scholar

  • Sourander, A. , Aromaa, M. , Pihlakoski, L. , Haavisto, A. , Rautava, P. , Helenius, H. et al. (2006). Eraly predictors of deliberate self-harm among adolescents. A prospective follow-up study from age 3 to age 15. Journal of Affective Disorders, 93, 87 – 96. First citation in articleCrossrefGoogle Scholar

  • Stanford, S. , Jones, M.P. (2009). Psychological subtyping finds pathological, impulsive, and ‘normal’ groups among adolescents who self-harm. Journal of Child Psychology and Psychiatry, 50, 807 – 815. First citation in articleCrossrefGoogle Scholar

  • Steiger, H. , Koerner, N. , Engelberg, M. J. , Israel, M. , Ng Ying Kin, N. M. K. , Young S. N., (2001). Self-destructiveness and seroronin function in bulimia nervosa. Psychiatry Research, 103, 15 – 26. First citation in articleCrossrefGoogle Scholar

  • Stiglmayr, C. E. , Shapiro, D. A. , Stieglitz, R. D. , Limberger, M. & Bohus, M. (2001). Experience of aversive tension and dissociation in female patients with borderline personality disorder–a controlled study. Journal of Psychiatric Research, 35, 111 – 118. First citation in articleCrossrefGoogle Scholar

  • Thompson, T. (1995). Self-injurious behavior as endogenous neurochemical self-administration. Mental Retardation in Developmental Disabilities Research Reviews, 1, 137 – 148. First citation in articleCrossrefGoogle Scholar

  • Tiefenbacher, S. , Novak, M. A. , Lutz, C. K. & Meyer, J. S. (2005). The physiology and neurochemistry of self-injurious behavior: A nonhuman primate model. Frontier Bioscience, 10, 1 – 11. First citation in articleCrossrefGoogle Scholar

  • Vonderlin, E. , Haffner, J. , Behrend, B. , Brunner, R. , Parzer, P. , Resch, F. (2011). Welche Probleme berichten Jugendliche mit selbstverletzenden Verhalten? Kindheit und Entwicklung, 20, 111 – 118. First citation in articleLinkGoogle Scholar

  • Von Kalckreuth, C. , Ludäscher, P. , Parzer, P. , Kaess, M. , Schmahl, C. , Bohus, M. et al. (in preparation). Pain perception in female adolescent patients with boderline personality disorder. First citation in articleGoogle Scholar

  • Wasserman, D. , Carli, V. , Wasserman, C. , Apter, A. , Balazs, J. , Bobes, J. et al. (2010). Saving and empowering young lives in Europe (SEYLE): A randomized controlled trial. BMC Public Health, 10, 192. First citation in articleCrossrefGoogle Scholar

  • Wilkinson P. & Goodyer, I. (2011). Non-suicidal self-injury. European Child and Adolescent Psychiatry, 20, 103 – 108. First citation in articleCrossrefGoogle Scholar

  • Wilkinson, P. , Kelvin, R. , Roberts, C. , Dubicka, B. & Goodyer, I. (2011). Clinical and psychosocial predictors of suicide attempts and nonsuicidal self-injury in the Adolescent Depression Antidepressants and Psychotherapy Trial (ADAPT). American Journal of Psychiatry, 168, 495 – 501. First citation in articleCrossrefGoogle Scholar