Abstract
Abstract We sought to determine if gender differences in cerebral blood flow velocity emerge while persons performed cognitive tasks known to favor men, e.g., tests of spatial abilities. Bilateral measures were obtained simultaneously from the middle cerebral artery (VMCA) by transcranial Doppler sonography while men and women college students performed 31-s thinking tasks. Tests of spatial ability included (1) three spatial visualizing tasks (finding words among sets of letters, locating pictures hidden within a complex scene, and finding embedded geometric patterns), and (2) a mental rotation task. Two nonspatial visualizing control tasks were looking at (1) a list of words and (2) a set of pictures. Women had significantly faster global VMCAs than men during all tasks except looking at pictures. Two tasks (looking at pictures, mental rotation) produced hemispheric asymmetry (right > left) in women only. Gender differences in the number of correct responses occurred for finding words (women > men) and mental rotation (paradoxically, men > women) but not the other tests of spatial abilities. Our study shows that transcranial Doppler sonography provides noninvasive, real-time physiological indices of gender differences in spatial abilities.
References
Ackerstaff, R.G. , Keunen, R.W. , van Pelt, W. , Montauban van Swijndregt, A.D. , Stijnen, T. (1990). Influence of biological factors on changes in mean cerebral blood flow velocity in normal aging: A transcranial Doppler study. Neurological Research, 12, 187– 191 .Bryden, M.P. (1980). Sex differences in brain organization: Different brains or different cognitive strategies?. Behavioral and Brain Sciences, 3, 230– 231 .Bulla-Hellwig, M. , Vollmer, J. , Götzen, A. , Skreczek, W. , Hartje, W. (1996). Hemispheric asymmetry of arterial blood flow velocity changes during verbal and visuospatial tasks. Neuropsychologia, 34, 987– 991 .Christensen, H. , Kopelman, M.D. , Stanhope, N. , Lorentz, L. , Owen, P. (1998). Rates of forgetting in Alzheimer dementia. Neuropsychologia, 36, 547– 557 .Cupini, L.M. , Matteis, M. , Troisi, E. , Sabbadini, M. , Bernardi, G. , Caltagirone, C. , Silvestrini, M. (1996). Bilateral simultaneous transcranial Doppler monitoring of flow velocity changes during visuospatial and verbal working memory tasks. Brain, 119, 1249– 1254 .Droste, D.W. , Harders, A.G. , Rastogi, E. (1989). A transcranial Doppler study of blood flow velocity in the middle cerebral arteries performed at rest and during mental activities. Stroke, 20, 1005– 1011 .Gur, R.C. , Gur, R.E. , Resnick, S.M. , Skolnick, B.E. , Alavi, A. , Reivich, M. (1987). The effect of anxiety on cortical cerebral blood flow and metabolism. Journal of Cerebral Blood Flow and Metabolism, 7, 173– 177 .Halpern, D. (1992). Sex differences in cognitive abilities (2nd. ed.). Hillsdale, NJ: Erlbaum .Halpern, D. (1997). Sex differences in intelligence: Implications for education. American Psychologist, 52, 1091– 1102 .Harders, A.G. , Laborde, G. , Droste, D.W. , Rastogi, E. (1989). Brain activity and blood flow velocity changes: a transcranial Doppler study. International Journal of Neuroscience, 47, 91– 102 .Hartje, W. , Ringelstein, E.B. , Kistinger, B. , Fabianek, D. , Willmes, K. (1994). Transcranial Doppler ultrasonic assessment of middle cerebral artery blood flow velocity changes during verbal and visuospatial cognitive tasks. Neuropsychologia, 32, 1443– 1452 .Horton-Lambirth, A. , Roberts, A.E. , McKinney, W.M. (1998). Cerebral blood flow velocities modulate during cognitive tasks using vision and vision-like requirements: ATCD study. Psychobiology, 26, 183– 189 .Kail, R. , Carter, P. , Pellegrino, J. (1979). The locus of sex differences in spatial ability. Perception & Psychophysics, 26, 182– 186 .Klingelhöfer, J. , Matzander, G. , Sander, D. , Schwarze, J. , Boecker, H. , Bischoff, C. (1997). Assessment of functional hemispheric asymmetry by bilateral simultaneous cerebral blood flow velocity monitoring. Journal of Cerebral Blood Flow and Metabolism, 17, 577– 585 .Knecht, S. , Henningsen, H. , Deppe, M. , Huber, T. , Ebner, A. , Ringelstein, E.-B. (1996). Successive activation of both cerebral hemispheres during cued word generation. NeuroReport, 7, 820– 824 .Kramer, J.H. , Delis, D.C. , Kaplan, E. , O'Donnell, L. , Prifitera, A. (1997). Developmental sex differences in verbal learning. Neuropsychology, 11, 577– 584 .Masters, M.S. (1998). The gender difference on the Mental Rotations test is not due to performance factors. Memory & Cognition, 26, 444– 448 .Matteis, M. , Silvestrini, M. , Troisi, E. , Cupini, L.M. , Caltagirone, C. (1997). Transcranial Doppler assessment of cerebral flow velocity during perception and recognition of melodies. Journal of the Neurological Sciences, 149, 57– 61 .Matteis, M. , Silvestrini, M. , Caltagirone, C. , Monaldo, B.C. , Troisi, E. (1998). Age and sex differences in cerebral hemodynamics: a transcranial Doppler study. Stroke, 29, 963– 967 .Raichle, M.E. (1994). Images of the mind: Studies with modern imaging techniques. Annual Review of Psychology, 45, 333– 356 .Rihs, F. , Gutbrod, K. , Gutbrod, B. , Steiger, H.-J. , Sturzenegger, M. , Mattle, H.P. (1995). Determination of cognitive hemispheric dominance by “stereo” transcranial Doppler sonography. Stroke, 26, 70– 73 .Schmelzeis, M.C. , Roberts, A.E. , McKinney, W.M. (1994). Cognitive activities modulate blood flow velocities in three cerebral arteries. Psychobiology, 22, 254– 258 .Schnittger, C. , Johannes, S. , Arnavaz, A. , Munte, T.F. (1997). Blood flow velocity changes in the middle cerebral artery induced by processing of hierarchical visual stimuli. Neuropsychologia, 35, 1181– 1184 .Shamma, F.N. , Fayad, P. , Brass, L. , Sarrel, P. (1992). Middle cerebral artery blood velocity during controlled ovarian hyperstimulation. Fertility & Sterility, 57, 1022– 1025 .Van De Graaff, K. , Fox, S.I. (1989). Concepts of human anatomy and physiology (2nd ed.). Dubuque, IA: Brown .von Reutern, G.-M. , von Büdingen, H.I. (1993). Ultrasound diagnosis of cerebrovascular disease . NY: Thieme Medical Publishers .Voyer, D. , Voyer, S. , Bryden, M.P. (1995). Magnitude of sex differences in spatial abilities. A meta-analysis and consideration of critical variables. Psychological Bulletin, 117, 250– 270 .Vriens, E.M. , Kraaier, V. , Musbach, M. , Wieneke, G.H. , van Huffelen, A.C. (1989). Transcranial pulsed Doppler measurements of blood velocity in the middle cerebral artery: reference values at rest and during hyperventilation in healthy volunteers in relation to age and sex. Ultrasound in Medicine & Biology, 15, 1– 8 .Wainer, H. (1991). Adjusting for differential base rates: Lord's paradox again. Psychological Bulletin, 109, 147– 151 .