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Original communication

Radial artery occlusion after cardiac catheterization and impact of medical treatment

Published Online:https://doi.org/10.1024/0301-1526/a000892

Summary:Background: The transradial artery approach is the preferred access for cardiac catheterization according to current guidelines. However, the most common complication is radial artery occlusion (RAO). Despite the rare indication for surgical reopening, the occluded radial artery is not available for further procedures or as a potential bypass graft. Still, treatment regimens for RAO are scarce. We now determined whether the addition of antithrombotic to antiplatelet therapy improves the rate of partial or complete regain of patency in RAO following transradial cardiac catheterization in a retrospective analysis. Patients and methods: In a two-center tertiary referral hospital retrospective analysis 4135 files of patients who had undergone transradial catheterization were screened for documented RAO. 141 patients were identified and 138 patients with complete information on the medical regimen and ultrasound examinations for a maximum of 3 months were included in the analysis, whereas 3 patients were excluded due to missing or incomplete follow-up information. Results: 3.3% of all patients that had undergone transradial catheterization featured an oligosymptomatic RAO, confirmed by color-coded duplex sonography. 21% of patients with additional anticoagulation regained full patency vs. 9% without additional anticoagulation (p = 0.07). 40% of patients with anticoagulation featured a partial or full regain of patency vs. 16% of patients without additional anticoagulation for a maximum of 3 months treatment (p = 0.006). No major bleedings were reported during the follow-up visits. Conclusions: RAO remains a rare complication of cardiac catheterization. The addition of antithrombotic therapy for 3 months appears to safely improve the partial or even full regain of radial patency in case of postinterventional RAO.

References

  • 1 Spaulding C, Lefèvre T, Funck F, Thébault B, Chauveau M, Hamda KB, et al. Left radial approach for coronary angiography: Results of a prospective study. Cathet Cardiovasc Diagn. 1996;39:365–70. First citation in articleCrossref MedlineGoogle Scholar

  • 2 Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F, et al. 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task force for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J. 2016;37:267–315. First citation in articleMedlineGoogle Scholar

  • 3 Wagener JF, Rao SV. Radial artery occlusion after transradial approach to cardiac aatheterization. Curr Atheroscler Rep. 2015;17:489. First citation in articleCrossref MedlineGoogle Scholar

  • 4 Kwok CS, Rashid M, Fraser D, Nolan J, Mamas M. Intra-arterial vasodilators to prevent radial artery spasm: A systematic review and pooled analysis of clinical studies. Cardiovasc Revasc Med. 2015;16:484–90. First citation in articleCrossref MedlineGoogle Scholar

  • 5 Rammos C, Burghardt A, Lortz J, Azizy O, Jánosi RA, Steinmetz M, et al. Impact of anticoagulation and vasoactive medication on regained radial artery patency after catheterization: A case-control study. Eur J Med Res. 2018;23:25. First citation in articleCrossref MedlineGoogle Scholar

  • 6 Nagai S, Abe S, Sato T, Hozawa K, Yuki K, Hanashima K, et al. Ultrasonic assessment of vascular complications in coronary angiography and angioplasty after transradial approach. Am J Cardiol. 1999;83:180–6. First citation in articleCrossref MedlineGoogle Scholar

  • 7 Hahalis GN, Leopoulou M, Tsigkas G, Xanthopoulou I, Patsilinakos S, Patsourakos NG, et al. Multicenter randomized evaluation of high versus standard heparin dose on incident radial arterial occlusion after transradial coronary angiography. JACC Cardiovasc Interv. 2018;11(22):2241–50. First citation in articleCrossref MedlineGoogle Scholar

  • 8 Zankl AR, Andrassy M, Volz C, Ivandic B, Krumsdorf U, Katus HA, et al. Radial artery thrombosis following transradial coronary angiography: Incidence and rationale for treatment of symptomatic patients with low-molecular-weight heparins. Clin Res Cardiol. 2010;99:841–7. First citation in articleCrossref MedlineGoogle Scholar

  • 9 Takeshita S, Asano H, Hata T, Hibi K, Ikari Y, Kan Y, et al. Comparison of frequency of radial artery occlusion after 4Fr versus 6Fr transradial coronary intervention (from the Novel Angioplasty USIng Coronary Accessor Trial). Am J Cardiol. 2014;113:1986–9. First citation in articleCrossref MedlineGoogle Scholar

  • 10 Dahm JB, Vogelgesang D, Hummel A, Staudt A, Völzke H, Felix SB. A randomized trial of 5 vs. 6 French transradial percutaneous coronary interventions. Catheter Cardiovasc Interv. 2002;57:172–6. First citation in articleCrossref MedlineGoogle Scholar