Skip to main content

Konzeptualisierung der Psychotherapie bei ADHS und Sucht

Published Online:https://doi.org/10.1024/0939-5911.a000387

Zusammenfassung.Zielsetzung: Das komorbide Auftreten der Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) und substanzbezogener Störungen (SUD) ist häufig und hat einen negativen Einfluss auf den Behandlungserfolg. Studien zur Wirksamkeit ADHS-spezifischer Medikamente bei dem komorbiden Auftreten beider Störungen kommen zu uneinheitlichen Ergebnissen. Einheitlich wird allerdings eine psychotherapeutische Behandlung bei dieser Patientengruppe empfohlen, während bislang jedoch kein evaluiertes Behandlungskonzept veröffentlich wurde. Ziel dieser Arbeit ist ein Überblick zu psychotherapeutischen Ansätzen bei beiden Störungsbildern und einen Ausblick auf psychotherapeutische Ansätze für das gemeinsame Auftreten beider Störungen zu geben. Methodik: Die Zusammenstellung der Literatur erfolgte auf Basis einer Medline-, PsycINFO- und Google Scholar-Recherche (Schlüsselwörter: substance abuse, adhd, psychotherapy, therapy, methylphenidate, atomoxetine, bupropion, CBT, relapse prevention, mindfulness, MBRP, DBT). Ergebnisse: Psychotherapeutische Ansätze zur Behandlung der ADHS im Erwachsenenalter und von SUD überschneiden sich inhaltlich. Als wirksam erweisen sich CBT- und achtsamkeitsbasierte Verfahren sowie die DBT. Schlussfolgerung: Eine Kombination der oben dargestellten therapeutischen Ansätze könnte bei der Behandlung einer komorbid auftretenden ADHS und SUD sinnvoll sein. Hier bedarf es weiterer Forschungsarbeit.


Psychotherapy for Co-occurring ADHD and SUD

Abstract.Aims: Attention-deficit hyperactivity disorder (ADHD) and substance use disorder (SUD) often co-occur, which makes treatment very difficult. Investigations into the effectiveness of ADHD medications in co-occurring ADHD and SUD have resulted in contradictory results, whereas psychotherapy is presently recommended. However, there is a lack of studies on suitable psychotherapeutic approaches. This article provides readers with information about combined psychotherapy for ADHD and SUD. Additionally, it provides a perspective on psychotherapeutic approaches for co-occurring ADHD and SUD. Methods: An overview of the literature was compiled from Medline, PsycINFO and Google Scholar (keywords: substance abuse, ADHD, psychotherapy, therapy, methylphenidate, atomoxetine, bupropion, CBT, relapse prevention, mindfulness, MBRP, DBT). Results: Psychotherapeutic approaches for ADHD and SUD overlap. CBT, mindfulness and DBT appear to be effective. Conclusions: A combination of approaches may be useful in the treatment of comorbid ADHD and SUD. Further investigation is required.

Literatur

  • Arias, A. J., Gelernter, J., Chan, G., Weiss, R. D., Brady, K. T. & Farrer, L., et al. (2008). Correlates of co-occurring ADHD in drug-dependent subjects: Prevalence and features of substance dependence and psychiatric disorders. Addictive Behaviors, 33, 1199 – 1207. First citation in articleCrossrefGoogle Scholar

  • Aviram, R. B., Rhum, M. & Levin, F. R. (2001). Psychotherapy of Adults with Comorbid Attention-Deficit/Hyperactivity Disorder and Psychoactive Substance Use Disorder. The Journal of Psychotherapy Practice and Research, 10, 179 – 186. First citation in articleGoogle Scholar

  • Bishop, S. R., Lau, M., Shapiro, S., Carlson, L., Anderson, N. D. & Carmody, J., et al. (2004). Mindfulness: A proposed operational definition. Clinical Psychology: Science and Practice, 11, 230 – 241. First citation in articleCrossrefGoogle Scholar

  • Bowen, S., Chawla, N., Collins, S. E., Witkiewitz, K., Hsu, S. & Grow, J., et al. (2009). Mindfulness-Based Relapse Prevention for Substance Use Disorders: A pilot Efficacy Trial. Substance Abuse, 30, 295 – 305. First citation in articleCrossrefGoogle Scholar

  • Bowen, S., Chawla, N. & Marlatt, G. A. (2010). Mindfulness-Based Relapse Prevention for Addictive Behaviors: A Clinician′s Guide. New York: Oxford Press. First citation in articleGoogle Scholar

  • Bowen, S., Witkiewitz, K., Clifasefi, S. L., Grow, J., Chawla, N. & Hsu, S. H., et al. (2014). Relapse efficacy of mindfulness-based relapse prevention, standard relapse prevention, and treatment as usual for substance use disorders: a randomized clinical trial. JAMA Psychiatry, 71, 547 – 556. First citation in articleCrossrefGoogle Scholar

  • Bueno, V. F., Kozasa, E. H., da Silva, M. A., Alves, T. M., Louzã, M. R. & Pompéia, S. (2015). Mindfulness Meditation Improves Mood, Quality of Life, and Attention in Adults with Attention Deficit Hyperactivity Disorder. BioMed Research International, 2015. Zugriff am 13. 07. 2015. Verfügbar unter www.ncbi.nlm.nih.gov/pmc/articels/PMC4475526. First citation in articleGoogle Scholar

  • Carpentier, P. J., van Gogh, M. T., Knapen, L. J. M., Buitelaar, J. K. & De Jong, C. A. J. (2011). Influence of Attention Deficit Hyperactivity Disorder and Conduct Disorder on Opioid Dependence and Psychiatric Comorbidity in Chronic Methadone-Maintained Patients. European Addiction Research, 17, 10 – 20. First citation in articleCrossrefGoogle Scholar

  • Chaney, E. R., O′Leary, M. R. & Marlatt, G. A. (1978). Skill training with alcoholics. Journal of Consulting and Clinical Psychology, 46, 1092 – 1104. First citation in articleCrossrefGoogle Scholar

  • Chang, Z., Lichtenstein, P., Halldner, L., D′Onofrio, B., Serlachius, E. & Fazel, S., et al. (2014). Stimulant ADHD medication and risk for substance abuse. Journal of Child Psychology and Psychiatry, 55, 878 – 885. First citation in articleCrossrefGoogle Scholar

  • Chiesa, A. & Serretti, A. (2014). Are Mindfulness-Based Interventions Effective for Substance Use Disorders? A Systematic Review of the Evidence. Substance Use & Misuse, 49, 492 – 512. First citation in articleCrossrefGoogle Scholar

  • Courbasson, C., Nishikawa, Y. & Dixon, L. (2012). Outcome of dialectical behaviour therapy for concurrent eating and substance use disorders. Clinical Psychology and Psychotherapy, 19, 434 – 449. First citation in articleCrossrefGoogle Scholar

  • Dakwar, E. & Levin, F. R. (2013). Individual mindfulness-based psychotherapy for cannabis or cocaine dependence: a pilot feasibility trial. American Journal of Addiction, 22, 521 – 526. First citation in articleCrossrefGoogle Scholar

  • Dalsgaard, S., Mortensen, P. B., Frydenberg, M. & Thomsen, P. H. (2014). ADHD, stimulant treatment in childhood and subsequent substance abuse in adulthood – A naturalistic long-term follow-up-study. Addictive Behaviors, 39, 325 – 328. First citation in articleCrossrefGoogle Scholar

  • Davis, M. L., Powers, M. B., Handelsman, P., Medina, J. L., Zvolensky, M. & Smits, J. A. J. (2015). Behavioral Therapies for Treatment-Seeking Cannabis-Users: A Meta-Analysis of Randomized Controlled Trials. Evaluation & the Health Profession, 38, 94 – 114. First citation in articleCrossrefGoogle Scholar

  • Dutra, L., Stathopoulou, G., Basden, S. L., Leyro, T. M., Powers, M. B. & Otto, M. W. (2008). A Meta-Analytic Review of Psychosocial Interventions for Substance Use Disorders. The American journal of psychiatry, 165, 179 – 187. First citation in articleCrossrefGoogle Scholar

  • Dimeff, L. A. & Linehan, M. M. (2008). Dialectical Behavior Therapy for Substance Abusers. Addiction Science and Clinical Practice, 4, 39 – 47. First citation in articleCrossrefGoogle Scholar

  • Ebert, D., Krause, J. & Roth-Sackenheim, C. (2003). ADHS im Erwachsenenalter – Leitlinien auf der Basis eines Expertenkonsensus mit Unterstützung der DGPPN. Der Nervenarzt, 10, 939 – 946. First citation in articleGoogle Scholar

  • Emilson, B., Gudjonsson, G., Sigurdsson, J. F., Baldursson, G., Einarsson, E. & Olafsdottir, H., et al. (2011). Cognitive behaviour therapy in medication-treated adults with ADHD and persistent Symptoms: A randomized controlled trial. BMC Psychiatry, 11, 116. First citation in articleCrossrefGoogle Scholar

  • Ercan, E. S., Coşkunol, H., Varan, A. & Toksöz, K. (2003). Childhood Attention Deficit/Hyperactivity Disorder and Alcohol Dependence: A 1-Year Follow-Up. Alcohol and Alcoholism, 38, 352 – 356. First citation in articleCrossrefGoogle Scholar

  • Hepark, S., Kan, C. C. & Speckens, A. E. M. (2014). Feasibility and effectiveness of mindfulness training in adults with ADHD: a pilot study. Tijdschrift voor Psychiatrie, 56, 471 – 476. First citation in articleGoogle Scholar

  • Hesslinger, B., Tebartz van Elst, L., Nyberg, E., Dykierek, P., Richter, H. & Berner, M., et al. (2002). Psychotherapy of attention deficit hyperactivity disorder in adults. European Archives of Psychiatry and Clinical Neuroscience, 252, 177 – 184. First citation in articleCrossrefGoogle Scholar

  • Hesslinger, B., Philipsen, A. & Richter, H. (2004). Psychotherapie der ADHS im Erwachsenenalter. Göttingen: Hogrefe. First citation in articleGoogle Scholar

  • Hirvikoski, T., Waaler, E., Alfredson, J, Pihlgren, C., Holmström, A. & Johnson, A., et al. (2011). Reduced ADHD symptoms in adults with ADHD after structured skills training group: Results from a randomized controlled trial. Behaviour Research and Therapy, 49, 175 – 85. First citation in articleCrossrefGoogle Scholar

  • Hofmann, S. G., Sawyer, A. T., Witt, A. A. & Oh, D. (2010). The effect of mindfulness-based therapy on anxiety and depression. Journal of Consulting and Clinical Psychology, 78, 169 – 183. First citation in articleCrossrefGoogle Scholar

  • Kalbag, A. S. & Levin, F. R. (2005). Adult ADHD and Substance Abuse: Diagnostic and Treatment Issues. Substance Use & Misuse, 40 (13 – 14), 1955 – 1981. First citation in articleCrossrefGoogle Scholar

  • Kessler, R. C., Berglund P., Demler O., Jin, R., Merikangas, K.R & Walters, E. E. (2005). Lifetime Prevalence and Age-of-Onset of DSM-VI Disorders in the National Comorbidity Survey Replication. Formerly Archives of General Psychiatry, 62, 593 – 602. First citation in articleCrossrefGoogle Scholar

  • Klein, R. G. (2002). Alcohol, stimulants, nicotine, and other drugs in ADHD. In P. S. JensenJ. R. CooperEds., Attention-Deficit/Hyperactivity Disorder: State of the Sciences/Best Practices. 16-1 – 16-17. Kingston (NJ): Civic Research Institute. First citation in articleGoogle Scholar

  • Kollins, S. H., English, J. S., Itchon-Ramos, N., Chrisman, A. K., Dew, R. & O′Brien, B., et al. (2014). A Pilot Study of Lis-Dexamphetamine Dimesylate (LDX/SPD489) to Facilitate Smoking Cessation in Nicotine-Dependent Adults With ADHD. Journal of Attention Disorders, 18, 158 – 168. First citation in articleCrossrefGoogle Scholar

  • Kolpe, M. & Carlson, G. A. (2007). Influence of Attention-Deficit/Hyperactivity Disorder Symptoms on Methadone Treatment Outcome. The American Journal on Addictions, 16, 46 – 48. First citation in articleCrossrefGoogle Scholar

  • Konstenius, M., Jayaram-Lindström, N., Guterstam, J., Beck, O., Philips, B. & Franck, J. (2014). Methylphenidate for ADHD in adults with substance dependence: A 24-week randomized placebo-controlled trial. Drug and Alcohol Dependence, 140, e109. First citation in articleGoogle Scholar

  • Kordon, A. & Kahl, K. G. (2004) Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung im Erwachsenenalter. Psychotherapie Psychosomatik Medizinische Psychotherapie, 54, 124 – 136. First citation in articleCrossrefGoogle Scholar

  • Lambert, N. M. & Hartsough, C. S. (1998). Prospective study of tobacco smoking and substance dependencies among samples of ADHD and non-ADHD-participants. Journal of Learning Disabilities, 31, 533 – 544. First citation in articleCrossrefGoogle Scholar

  • Lee, S. S., Humphreys, K. L., Flory, K., Liu, R. & Glass, K. (2011). Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: A meta-analytic review. Clinical Psychology Review, 31, 328 – 341. First citation in articleCrossrefGoogle Scholar

  • Levin, F. R., Evans, S. M., Vosburg, S. K., Horton, T., Brooks, D. & Ng, J. (2004). Impact of attention-deficit hyperactivity disorder and other psychopathology on treatment retention among cocaine abusers in a therapeutic community. Addictive Behaviors, 29, 1875 – 1882. First citation in articleCrossrefGoogle Scholar

  • Levin, F. R., Evans, S. M., Brooks, D. J., Kalbag, A. S., Garawi, F. & Nunes, E. V. (2006). Treatment of methadone-maintained patients with adult ADHD: Double-blind comparison of methylphenidate, bupropion and placebo. Drug and Alcohol Dependence, 81, 137 – 148. First citation in articleCrossrefGoogle Scholar

  • Levin, F. R., Evans, S. M., Brooks, D. J. & Garawi, F. (2007). Treatment of cocaine dependent treatment seekers with adult ADHD: Double-blind comparison of methylphenidate and placebo. Drug and Alcohol Dependence, 87, 20 – 29. First citation in articleCrossrefGoogle Scholar

  • Levin, F.R, Mariani, J. J., Specker, S., Mooney, M., Mahony, A. & Brooks, D. J., et al. (2015). Extended-Release Mixed Amphetamine Salts vs Placebo for Comorbid Adult Attention-Deficit/Hyperactivity Disorder and Cocaine Use Disorder. JAMA Psychiatry, 72, 593 – 602. First citation in articleCrossrefGoogle Scholar

  • Linehan, M. M., Armstrong, H. E., Suarez, A., Allmon, D. & Heard, H. L. (1991). Cognitive-Behavioral Treatment of Chronically Parasuicidal Borderline Patients. Formerly Archives of General Psychiatry, 48, 1060 – 1064. First citation in articleCrossrefGoogle Scholar

  • Linehan, M. M., Schmidt, H. S., Dimeff, L. A., Craft, C., Kanter, J. & Comtois, K. A. (1999). Dialectical Behavior Therapy with Borderline Personality Disorder and Drug-Dependence. The American Journal of Addictions, 8, 279 – 292. First citation in articleCrossrefGoogle Scholar

  • Linehan, M. M., Dimeff, L. A., Reynolds, S. K., Comtois, K. A., Welch, S. S., Heagerty, P. & Kivlahan, D. R. (2002). Dialectical behavior therapy versus comprehensive validation therapy plus 12-step for the treatment of opioid dependent women meeting criteria for borderline personality disorder. Drug and Alcohol Dependence, 67, 13 – 26. First citation in articleCrossrefGoogle Scholar

  • Magill, M. & Ray, L. A. (2009). Cognitive-Behavioral Treatment with adult alcohol and illicit drug users: A Meta-Analysis of Randomized Controlled Trials. Journal of Studies on Alcohol and Drugs, 70, 516 – 527. First citation in articleCrossrefGoogle Scholar

  • Marlatt, G. A. (1985). Relapse prevention: Theoretical overview of the model. In G. A. MarlattJ. R. GordonEds., Relapse prevention (pp. 3 – 70). New York: Guilford. First citation in articleGoogle Scholar

  • McRae-Clark, A. L., Carter, R. E., Killeen, T. K., Carpenter, M. J., White, K. G. & Brady, K. T. (2010). A Placebo-Controlled Trial of Atomoxetine in Marijuana-Dependent Individuals with Attention Deficit Hyperactivity Disorder. The American Journal on Addictions, 19, 481 – 489. First citation in articleCrossrefGoogle Scholar

  • Pitts, M., Mangle, L. & Asherson, P. (2015). Impairments, Diagnosis and Treatments Associated with Attention-Deficit/Hyperactivity Disorder (ADHD) in UK Adults: Results from the Lifetime Impairment Survey. Archieves of Psychiatric Nursing, 29, 56 – 63. First citation in articleCrossrefGoogle Scholar

  • Philipsen, A., Richter, H., Peters, J., Alm, B., Sobanski, E. & Colla, M., et al. (2007). Structured Group Psychotherapy in Adults With Attention Deficit Hyperactivity Disorder: Results of An Open Multicentre Study. The Journal of Nervous and Mental Disease, 195, 1013 – 1019. First citation in articleCrossrefGoogle Scholar

  • Riggs, P. D., Winhusen, T., Davies, R. D., Leimberger, J. D., Mikulich-Gilbertson, S. & Klein, C., et al. (2011). Randomized Controlled Trial of Osmotic-Release Methylphenidate with CBT in Adolescents with ADHD and Substance Use Disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 50, 903 – 914. First citation in articleCrossrefGoogle Scholar

  • Rösler, M. & Retz, W. (2007). Sozialmedizinische Aspekte der ADHS. PsychoNeuro, 33, 390 – 394. First citation in articleCrossrefGoogle Scholar

  • Rostain, A. L. & Ramsay, J. R. (2006). A Combined Treatment Approach for Adults With ADHD – Results of an Open Study of 43 Patients. Journal of Attention Disorders, 10, 150 – 159. First citation in articleCrossrefGoogle Scholar

  • Safren, S. A., Sprich, S., Mimiaga, M. J., Surman, C., Knouse, L. & Groves, M., et al. (2010). Cognitive Behavioral Therapy vs Relaxation With Educational Support for Medication-Treated Adults With ADHD and Persistent Symptoms. The Journal of the American Medical Association, 304, 875 – 880. First citation in articleCrossrefGoogle Scholar

  • Schoenberg, P. L. A., Hepark, S., Kan, C. C., Barendregt, H. P., Buitelaar, J. K. & Speckens, A. E. M. (2014). Effects of mindfulness-based cognitive therapy on neurophysiological correlates of performance monitoring in adult attention-deficit/hyperactivity disorder. Clinical Neurophysiology, 125, 1407 – 1416. First citation in articleCrossrefGoogle Scholar

  • Sobanski, E. & Alm, B. (2004). Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung bei Erwachsenen. Nervenarzt, 75, 697 – 716. First citation in articleCrossrefGoogle Scholar

  • Solhkhah, R., Wilens, T. E., Daly, J., Prince, J. B., Van Patten, S. L. & Biederman, J. (2005). Bupropion SR for the Treatment of Substance-Abusing Outpatient Adolescents with Attention-Deficit/Hyperactivity Disorder and Mood Disorders. Journal of Child and Adolescent Psychopharmacology, 15, 777 – 786. First citation in articleCrossrefGoogle Scholar

  • Stevenson, C. S., Withmont, S., Bornholt, L., Livesey, D. & Stevenson, R. J. (2002) A cognitive remediation programme for adults with attention deficit hyperactivity disorder. Australian and New Zealand Journal of Psychiatry, 36, 610 – 616. First citation in articleCrossrefGoogle Scholar

  • Thurstone, C., Riggs, P. D., Salomonsen-Sautel, S. & Mikulich-Gilbertson, S. K. (2010). Randomized, Controlled Trial of Atomoxetine for Attention-Deficit/Hyperactivity Disorder in Adolescents With Substance Use Disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 49, 573 – 582. First citation in articleGoogle Scholar

  • Van Emmerik –van Oortmerssen, K., Vedel, E., Koeter, M. W., de Bruijn, K., Dekker, J. J., & van den Brink, W. et al. (2013). Investigating the efficacy of integrative cognitive behavioral therapy for adult treatment seeking substance use disorder patients with comorbid ADHD: study protocol of a randomized controlled trial. BMC Psychiatry, 13, 132. First citation in articleCrossrefGoogle Scholar

  • Van Emmerik-van Oortmerssen, K., Vedel, E., van den Brink, W. & Schoevers, R. A. (2015). Integrated cognitive behavioral therapy for patients with Substance Use Disorder and Comorbid ADHD: Two case presentations. Addictive Behaviors, 45, 214 – 217. First citation in articleCrossrefGoogle Scholar

  • White, A. M., Jordan, J. D., Schroeder, K. M., Acheson, S. K., Georgi, B. D. & Sauls, G., et al. (2004). Predictors of Relapse During Treatment and Treatment Completion Among Marijuana-Dependent Adolescents in an Intensive Outpatient Substance Abuse Program. Substance Abuse, 25, 53 – 59. First citation in articleCrossrefGoogle Scholar

  • Wilens, T. E., Biederman, J & Mick, E. (1998). Does ADHD affect the course of substance abuse? Findings from a sample of adults with and without ADHD. The American Journal on Addictions, 7, 156 – 163. First citation in articleGoogle Scholar

  • Wilens, T. E., Faraone, S. V., Biederman, J. & Gunawardene, S. (2003). Does Stimulant Therapy of Attention-Deficit/Hyperactivity Disorder Beget Later Substance Abuse? A Meta-Analytic Review of the Literature. Pediatrics, 111, 179 – 185. First citation in articleCrossrefGoogle Scholar

  • Wilens, T. E. (2004). Attention-deficit/hyperactivity disorder and the substance use disorders: the nature of the relationship, subtypes at risk and treatment issues. The Psychiatric Clinics of North America, 27, 283 – 301. First citation in articleCrossrefGoogle Scholar

  • Wilens, T. E., Prince, J. B., Waxmonsky, J., Doyle, R., Spencer, T. & Martelon, M. K., et al. (2010). An Open Trial of Sustained Release Bupropion for Attention-Deficit/Hyperactivity Disorder in Adults with ADHD plus Substance Use Disorders. Journal of ADHD Related Disorders, 1, 25 – 35. First citation in articleGoogle Scholar

  • Wilens, T. E., Adler, L. A., Tanaka, Y., Xiao, F., D′Souza, D. N. & Gutkin, S. W., et al. (2011). Correlates of alcohol use in adults with ADHD and comorbid alcohol use disorders: exploratory analysis of placebo-controlled trial of atomoxetine. Current Medical Research & Opinion, 27, 2309 – 2320. First citation in articleCrossrefGoogle Scholar

  • Winhusen, T. M., Somoza, E. C., Brigham, G. S., Liu, D. S., Green, C. A. & Covey, L. S., et al. (2010). Does treatment of Attention Deficit Hyperactivity Disorder (ADHD) enhance response to smoking cessation intervention in ADHD smokers? A randomized trial. The Journal of clinical psychiatry, 71, 1680 – 1688. First citation in articleCrossrefGoogle Scholar

  • Witkiewitz, K., Warner, K., Sully, B., Barricks, A., Stauffer, C. & Thompson, B. L., et al. (2014). Randomized trial comparing mindfulness-based relapse prevention with relapse prevention for women offenders at a residential addiction treatment center. Substance Use & Misuse, 49, 536 – 46. First citation in articleCrossrefGoogle Scholar

  • Zylowska, L., Ackerman, D. L., Yang, M. H., Futrell, J. L., Horton, N. L., & Hale, T. S. et al. (2008). Mindfulness meditation training in adults and adolescents with ADHD: A feasibility study. Journal of Attention Disorders, 11, 737 – 46. First citation in articleCrossrefGoogle Scholar