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Free AccessOriginal communication

A prospective survey study on the education and awareness about walking exercise amongst inpatients with symptomatic peripheral arterial disease in Germany

Published Online:https://doi.org/10.1024/0301-1526/a001057

Summary:Background: To determine the adherence to supervised exercise training and underlying reasons for non-adherence amongst patients with inpatient treatment of symptomatic lower extremity peripheral arterial disease (PAD). Patients and methods: This was a prospective questionnaire-based survey study of all consecutively treated inpatients with treatment for either intermittent claudication or chronic limb-threatening ischaemia (CLTI) surveyed at sixteen participating centres in Germany. Results: A total of 235 patients (median age 70 years) were included, thereof 29.4% females and 34.6% with CLTI. The median time from first PAD diagnosis was 4 years (IQR: 1–8). Only 11.4% have previously participated in any walking exercise programme before the index treatment, thereby 10.0% in the IC subgroup and 12.0% with CLTI. Amongst all patients, 35.6% responded they were appropriately informed about the necessity and benefits of walking exercise programmes by their hospital physicians (25.8% by general practitioners), and 65.3% agreed that adherence to supervised exercise may improve their pain-free walking distance. A total of 24.5% responded they had access to necessary information concerning local walking exercise programmes. Amongst 127 free text comments on the reasons for non-adherence to supervised exercise training, 64% of the comments contained lack of information or consent on such measures. Conclusions: Less than 12% of the patients enrolled in the current study have ever participated in a walking exercise programme during their life course. Although all practice guidelines contain corresponding class I recommendations, especially for patients suffering from IC, most patients responded that they were not appropriately informed about the necessity of exercise training along with the fact that 65% agreed that exercise may increase the pain-free walking distance. Taken all together, these results emphasise that we miss an important opportunity in the patient-physician communication. Efforts should be made to improve acceptance and application of structured walking-exercise for patients with PAD.

References

  • 1 Song P, Rudan D, Zhu Y, Fowkes FJI, Rahimi K, Fowkes FGR, et al. Global, regional, and national prevalence and risk factors for peripheral artery disease in 2015: an updated systematic review and analysis. Lancet Glob Health. 2019;7(8):e1020–e30. First citation in articleCrossref MedlineGoogle Scholar

  • 2 Aboyans V, Ricco JB, Bartelink MEL, Bjorck M, Brodmann M, Cohnert T, et al. Editor’s Choice – 2017 ESC guidelines on the diagnosis and treatment of peripheral arterial diseases, in collaboration with the European Society for Vascular Surgery (ESVS). Eur J Vasc Endovasc Surg. 2018;55(3):305–68. First citation in articleCrossref MedlineGoogle Scholar

  • 3 Gerhard-Herman MD, Gornik HL, Barrett C, Barshes NR, Corriere MA, Drachman DE, et al. 2016 AHA/ACC guideline on the management of patients with lower extremity peripheral artery disease: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2017;69(11):e71–e126. First citation in articleCrossref MedlineGoogle Scholar

  • 4 Hiatt WR, Goldstone J, Smith SC Jr, McDermott M, Moneta G, Oka R, et al. Atherosclerotic Peripheral Vascular Disease Symposium II: nomenclature for vascular diseases. Circulation. 2008;118(25):2826–9. First citation in articleCrossref MedlineGoogle Scholar

  • 5 McDermott MM, Greenland P, Liu K, Guralnik JM, Criqui MH, Dolan NC, et al. Leg symptoms in peripheral arterial disease: associated clinical characteristics and functional impairment. JAMA. 2001;286(13):1599–606. First citation in articleCrossref MedlineGoogle Scholar

  • 6 Smolderen KG, Pelle AJ, Kupper N, Mols F, Denollet J. Impact of peripheral arterial disease on health status: a comparison with chronic heart failure. J Vasc Surg. 2009;50(6):1391–8. First citation in articleCrossref MedlineGoogle Scholar

  • 7 Olsen PS, Gustafsen J, Rasmussen L, Lorentzen JE. Long-term results after arterial surgery for arteriosclerosis of the lower limbs in young adults. Eur J Vasc Surg. 1988;2(1):15–8. First citation in articleCrossref MedlineGoogle Scholar

  • 8 Hiatt WR, Hirsch AT, Regensteiner JG, Brass EP. Clinical trials for claudication. Assessment of exercise performance, functional status, and clinical end points. Vascular Clinical Trialists. Circulation. 1995;92(3):614–21. First citation in articleCrossref MedlineGoogle Scholar

  • 9 Lawall H, Huppert P, Espinola-Klein C, Rümenapf G. The diagnosis and treatment of peripheral arterial vascular disease. Dtsch Arztebl Int. 2016;113(43):729–36. First citation in articleMedlineGoogle Scholar

  • 10 Firnhaber JM, Powell CS. Lower extremity peripheral artery disease: diagnosis and treatment. Am Fam Physician. 2019;99(6):362–9. First citation in articleMedlineGoogle Scholar

  • 11 Murphy TP, Cutlip DE, Regensteiner JG, Mohler ER, Cohen DJ, Reynolds MR, et al. Supervised exercise versus primary stenting for claudication resulting from aortoiliac peripheral artery disease: six-month outcomes from the claudication: exercise versus endoluminal revascularization (CLEVER) study. Circulation. 2012;125(1):130–9. First citation in articleCrossref MedlineGoogle Scholar

  • 12 Hageman D, Fokkenrood HJ, Gommans LN, van den Houten MM, Teijink JA. Supervised exercise therapy versus home-based exercise therapy versus walking advice for intermittent claudication. Cochrane Database Syst Rev. 2018;4:CD005263. First citation in articleMedlineGoogle Scholar

  • 13 Savage P, Ricci MA, Lynn M, Gardner A, Knight S, Brochu M, et al. Effects of home versus supervised exercise for patients with intermittent claudication. J Cardiopulm Rehabil. 2001;21(3):152–7. First citation in articleCrossref MedlineGoogle Scholar

  • 14 Frank U, Nikol S, Belch J, Boc V, Brodmann M, Carpentier PH, et al. ESVM Guideline on peripheral arterial disease. Vasa. 2019;48 Suppl 102:1–79. First citation in articleAbstractGoogle Scholar

  • 15 Elgersma KM, Brown RJL, Salisbury DL, Stigen L, Gildea L, Larson K, et al. Adherence and exercise mode in supervised exercise therapy for peripheral artery disease. J Vasc Nurs. 2020;38(3):108–17. First citation in articleCrossref MedlineGoogle Scholar

  • 16 Ahimastos AA, Pappas EP, Buttner PG, Walker PJ, Kingwell BA, Golledge J. A meta-analysis of the outcome of endovascular and noninvasive therapies in the treatment of intermittent claudication. J Vasc Surg. 2011;54(5):1511–21. First citation in articleCrossref MedlineGoogle Scholar

  • 17 Nordanstig J, Gelin J, Hensater M, Taft C, Osterberg K, Jivegard L. Walking performance and health-related quality of life after surgical or endovascular invasive versus non-invasive treatment for intermittent claudication – a prospective randomised trial. Eur J Vasc Endovasc Surg. 2011;42(2):220–7. First citation in articleCrossref MedlineGoogle Scholar

  • 18 Pandey A, Banerjee S, Ngo C, Mody P, Marso SP, Brilakis ES, et al. Comparative Efficacy of Endovascular Revascularization Versus Supervised Exercise Training in Patients With Intermittent Claudication: Meta-Analysis of Randomized Controlled Trials. JACC Cardiovasc Interv. 2017;10(7):712–24. First citation in articleCrossref MedlineGoogle Scholar

  • 19 Baubeta Fridh E, Andersson M, Thuresson M, Sigvant B, Kragsterman B, Johansson S, et al. Amputation rates, mortality, and pre-operative comorbidities in patients revascularised for intermittent claudication or critical limb ischaemia: a population based study. Eur J Vasc Endovasc Surg. 2017;54(4):480–6. First citation in articleCrossref MedlineGoogle Scholar

  • 20 Kreutzburg T, Peters F, Kuchenbecker J, Marschall U, Lee R, Kriston L, et al. Editor’s Choice – The GermanVasc Score: a pragmatic risk score predicts five year amputation free survival in patients with peripheral arterial occlusive disease. Eur J Vasc Endovasc Surg. 2021;61(2):248–56. First citation in articleCrossref MedlineGoogle Scholar

  • 21 Peters F, Kreutzburg T, Riess HC, Heidemann F, Marschall U, L’Hoest H, et al. Editor’s Choice – Optimal pharmacological treatment of symptomatic peripheral arterial occlusive disease and evidence of female patient disadvantage: an analysis of health insurance claims data. Eur J Vasc Endovasc Surg. 2020;60(3):421–9. First citation in articleCrossref MedlineGoogle Scholar

  • 22 Pastori D, Farcomeni A, Milanese A, Del Sole F, Menichelli D, Hiatt WR, et al. Statins and major adverse limb events in patients with peripheral artery disease: a systematic review and meta-analysis. Thromb Haemost. 2020;120(5):866–75. First citation in articleCrossref MedlineGoogle Scholar

  • 23 Kokkinidis DG, Arfaras-Melainis A, Giannopoulos S, Katsaros I, Jawaid O, Jonnalagadda AK, et al. Statin therapy for reduction of cardiovascular and limb-related events in critical limb ischemia: A systematic review and meta-analysis. Vasc Med. 2020;25(2):106–17. First citation in articleCrossref MedlineGoogle Scholar

  • 24 Conte MS, Bradbury AW, Kolh P, White JV, Dick F, Fitridge R, et al. Global vascular guidelines on the management of chronic limb-threatening ischemia. Eur J Vasc Endovasc Surg. 2019;58(1S):S1–S109.e33. First citation in articleCrossref MedlineGoogle Scholar

  • 25 Alushi K, Hinterseher I, Peters F, Rother U, Bischoff MS, Mylonas S, et al. Distribution of mobile health applications amongst patients with symptomatic peripheral arterial disease in Germany: a cross-sectional survey study. J Clin Med. 2022;11(3):498. First citation in articleCrossref MedlineGoogle Scholar