Glutamate is the major mediator of excitatory signals in the mammalian central nervous system. Extreme amounts of glutamate in the extracellular spaces can lead to numerous neurodegenerative diseases. We aimed to clarify the potential of the following ...
New developments in the psychotherapeutic and pharmacological treatment of pediatric obsessivecompulsive disorder Abstract. Cognitive-behavioral therapy (CBT) and selective-serotonin reuptake inhibitors (SSRI) ...
Abstract.Objective: Research has implicated glutamatergic projections between the various frontal subregions in the pathogenesis of compulsivity and impulsivity. Reducing striatal glutamate release, or antagonising ...
Pharmacotherapy of Sleep-Wake DisordersAbstract. Sleep is a complex behavior, coordinated by many different brain regions and neurotransmitters. These neurochemical systems can be pharmacologically influenced to modulate ...
Molecular Mechanisms of Opiate AddictionObjective: A review is given over the biological basis and molecular mechanisms in opiate addiction. </P><P>
Method: Systematic analysis of the literature and own findings. </P><P>
Results: The mesolimbic reward ...
Abstract. Inflammational-immunological processes within the pathophysiology of schizophrenia seem to play an important role. Early signals of neurobiological changes in the embryonal phase of brain in later patients with schizophrenia ...