Skip to main content
Übersichtsarbeit

Trauma und Sucht: Implikationen für die Psychotherapie

Published Online:https://doi.org/10.1024/0939-5911.a000191

Ziel: Die vorliegende narrative Übersichtsarbeit geht der Frage nach, welche Rolle traumatische Lebenserfahrungen und damit assoziierte Traumafolgestörungen bezüglich der Ätiologie und Pathogenese von Suchterkrankungen spielen und welche Implikationen sich daraus für die therapeutische Praxis ableiten. Ergebnisse: Die aktuelle empirische Befundlage belegt ein gehäuftes gemeinsames Auftreten von traumatischen Erfahrungen und substanzbezogenen Störungen sowie eine erhöhte Komorbidität von Posttraumatischer Belastungsstörung und Suchterkrankungen. Befunde aus Interview- und Fragebogenstudien sowie aus experimentellen Untersuchungen mit komorbiden Patienten zeigen, dass Betroffene psychotrope Substanzen als Selbstmedikation einsetzen, um ihre traumabedingte Symptomatik zu lindern. Es entsteht ein komplexes, sich gegenseitig aufrechterhaltendes Wechselspiel zwischen Traumafolge- und Suchtsymptomatik, welches die Behandlung deutlich erschwert. Schlussfolgerungen: Zur Unterbrechung dieses Wechselspiels erscheint ersten Befunden zufolge ein von Beginn an integrativer, traumafokussierter Behandlungsansatz besonders geeignet. Auch wenn diesbezüglich erste erfolgsversprechende traumakonfrontative Therapieansätze entwickelt wurden, stehen größere prospektive Untersuchungen sowie randomisiert kontrollierte Therapiestudien diesbezüglich noch aus und sollten einen Schwerpunkt zukünftiger Forschung auf diesem Gebiet bilden.


Trauma and Addiction: Implications for Psychotherapy

Aim: This narrative review focuses on the question of how traumatic life experiences and trauma-related disorders are implicated in the etiology and pathogenesis of addiction and the resulting implications for psychotherapy. Results: Current empirical evidence shows numerous co-occurrence of traumatic experiences and substance use disorders as well as an increased comorbidity of post-traumatic stress disorder and addiction. Findings from various clinical studies with patients suffering from trauma and substance related disorders point out that these individuals use psychotropic substances as a self-medication to alleviate trauma-related symptoms. This often results in a complex interaction between trauma sequelae and addiction symptoms whereby both conditions mutually sustain each other. Conclusions: This has important implications for the treatment of addiction. Preliminary evidence shows that, rather than focusing on the symptoms of addiction only, integrated approaches with a trauma focus should be applied in order to interrupt the vicious circle between trauma and substance use disorders. So far, first promising trauma focused treatment approaches have been developed, but there is still a paucity of large-scale prospective surveys as well as randomized controlled trials. Such empirical studies should be a priority for future research on this topic.

Literatur

  • Annis, H. M. , Graham, J. M. & Davis, C. S. (1987). Inventory of Drinking Situations (IDS) User’s Guide. Toronto: Addiction Research Foundation. First citation in articleGoogle Scholar

  • Back, S. E. (2010). Toward an improved model of treating co-occurring PTSD and substance use disorders. American Journal of Psychiatry, 167, 11 – 13. First citation in articleCrossrefGoogle Scholar

  • Back, S. E. , Brady, K. T. , Jaanimagi, U. & Jackson, C. L. (2006). Cocaine dependence and PTSD: A pilot study of symptom interplay and treatment preferences. Addictive Behaviors, 31, 351 – 354. First citation in articleCrossrefGoogle Scholar

  • Brady, K. T. (1997). Posttraumatic stress disorder and comorbidity: Recognizing the many faces of PTSD. The Journal of Clinical Psychiatry, 5(Suppl. 9), 12 – 15. First citation in articleGoogle Scholar

  • Brady, K. T. , Back, S. E. & Coffey, S. F. (2004). Substance abuse and posttraumatic stress disorder. Current Directions in Psychological Science, 13, 206 – 209. First citation in articleCrossrefGoogle Scholar

  • Brady, K. T. , Dansky, B. S. , Back, S. E. , Foa, E. B. & Carroll, K. M. (2001). Exposure therapy in the treatment of PTSD among cocaine-dependent individuals. Journal of Substance Abuse Treatment, 21, 47 – 54. First citation in articleCrossrefGoogle Scholar

  • Brems, C. & Namyniuk, L. (2002). The relationship of childhood abuse history and substance use in an Alaska sample. Substance Use & Misuse, 37, 473 – 494. First citation in articleCrossrefGoogle Scholar

  • Brems, C. , Johnson, M. E. , Neal, D. & Freemon, M. (2004). Childhood abuse history and substance use among men and women receiving detoxification services. The American Journal of Drug and Alcohol Abuse, 30, 799 – 821. First citation in articleCrossrefGoogle Scholar

  • Brown, P. (2000). Outcome in female patients with both substance use and post-traumatic stress disorders. Alcoholism Treatment Quarterly, 18, 127 – 135. First citation in articleCrossrefGoogle Scholar

  • Brown, P. J. & Wolfe, J. (1994). Substance abuse and post-traumatic stress disorder comorbidity. Drug and Alcohol Dependence, 35, 51 – 59. First citation in articleCrossrefGoogle Scholar

  • Bundespsychotherapeutenkammer (2011). Ambulante Psychotherapie für Suchtkranke verbessert: G-BA ändert Psychotherapie-Richtlinie. Zugriff am 04. 10. 2011. Verfügbar unter: www.bptk.de/uploads/media/110414_PM_BPtK_Ambulante_Psychotherapie_f%C3 %BCr_Suchtkranke_verbessert.pdf First citation in articleGoogle Scholar

  • Chapman, D. P. , Dube, S. R. & Anda, R. F. (2007). Adverse childhood events as risk factors for negative mental health outcomes. Psychiatric Annals, 37, 359 – 364. First citation in articleGoogle Scholar

  • Clark, D. B. , Lesnick, L. & Hegedus, A. M. (1997). Traumas and other adverse life events in adolescents with alcohol abuse and dependence. Journal of the American Academy of Child & Adolescent Psychiatry, 36, 1744 – 1751. First citation in articleCrossrefGoogle Scholar

  • Coffey, S. F. , Dansky, B. S. & Brady, K. T. (2003). Exposure-based, trauma-focused therapy for comorbid posttraumatic stress disorder-substance use disorder. In P. Ouimette & P. J. Brown (Eds.), Trauma and substance abuse. Causes, consequences, and treatment of comorbid disorders (1st ed., pp. 127 – 146). Washington, DC: American Psychological Association. First citation in articleCrossrefGoogle Scholar

  • Coffey, S. F. , Read, J. P. & Norberg, M. M. (2007). Posttraumatic stress disorder and substance use disorder: Neuroimaging, neuroendocrine, and psychophysiological findings. In S. Stewart & P. Conrod (Eds.), Anxiety and substance use disorders: The vicious cycle of comorbidity (pp. 37 – 57). New York: Springer. First citation in articleGoogle Scholar

  • Coffey, S. F. , Schumacher, J. A. , Stasiewicz, P. R. , Henslee, A. M. , Baillie, L. E. & Landy, N. (2010). Craving and physiological reactivity to trauma and alcohol cues in posttraumatic stress disorder and alcohol dependence. Experimental and Clinical Psychopharmacology, 18, 340 – 349. First citation in articleCrossrefGoogle Scholar

  • Coffey, S. F. , Stasiewicz, P. R. , Hughes, P. M. & Brimo, M. L. (2006). Trauma-focused imaginal exposure for individuals with comorbid posttraumatic stress disorder and alcohol dependence: Revealing mechanisms of alcohol craving in a cue reactivity paradigm. Psychology of Addictive Behaviors, 20, 425 – 435. First citation in articleCrossrefGoogle Scholar

  • Cooper, M. L. (1994). Motivations for alcohol use among adolescents: Development and validation of a four-factor model. Psychological Assessment, 6, 117 – 128. First citation in articleCrossrefGoogle Scholar

  • Cottler, L. B. , Compton, W. M. , Mager, D. , Spitznagel, E. L. & Janca, A. (1992). Posttraumatic stress disorder among substance users from the general population. The American Journal of Psychiatry, 149, 664 – 670. First citation in articleCrossrefGoogle Scholar

  • Danielson, C. K. , Amstadter, A. B. , Dangelmaier, R. E. , Resnick, H. S. , Saunders, B. E. & Kilpatrick, D. G. (2009). Does typography of substance abuse and dependence differ as a function of exposure to child maltreatment? Journal of Child & Adolescent Substance Abuse, 18, 323 – 342. First citation in articleCrossrefGoogle Scholar

  • Dass-Brailsford, P. & Myrick, A. C. (2010). Psychological trauma and substance abuse: The need for an integrated approach. Trauma, Violence & Abuse, 11, 202 – 213. First citation in articleCrossrefGoogle Scholar

  • Deutsche Hauptstelle für Suchtfragen e.V. (DHS). (2010). Jahrbuch Sucht 2010. Geesthacht: Neuland. First citation in articleGoogle Scholar

  • Dilling, H. (2006). Internationale Klassifikation psychischer Störungen: ICD-10 Kapitel V (F). Diagnostische Kriterien für Forschung und Praxis. Bern: Huber. First citation in articleGoogle Scholar

  • Douglas, K. R. , Chan, G. , Gelernter, J. , Arias, A. J. , Anton, R. F. , Weiss, R. D. et al. (2010). Adverse childhood events as risk factors for substance dependence: Partial mediation by mood and anxiety disorders. Addictive Behaviors, 35, 7 – 13. First citation in articleCrossrefGoogle Scholar

  • Driessen, M. , Schulte, S. , Luedecke, C. , Schaefer, I. , Sutmann, F. , Ohlmeier, M. et al. (2008). Trauma and PTSD in patients with alcohol, drug, or dual dependence: A multi-center study. Alcoholism: Clinical and Experimental Research, 32, 481 – 488. First citation in articleCrossrefGoogle Scholar

  • Dube, S. R. , Anda, R. F. , Felitti, V. J. , Edwards, V. J. & Croft, J. B. (2002). Adverse childhood experiences and personal alcohol abuse as an adult. Addictive Behaviors, 27, 713 – 725. First citation in articleCrossrefGoogle Scholar

  • Ehlers, A. & Clark, D. M. (2000). A cognitive model of posttraumatic stress disorder. Behaviour Research and Therapy, 38, 319 – 345. First citation in articleCrossrefGoogle Scholar

  • Euser, E. M. , van Ijzendoorn, M. H. , Prinzie, P. & Bakermans-Kranenburg, M. J. (2010). Prevalence of child maltreatment in the Netherlands. Child Maltreatment, 15, 5 – 17. First citation in articleCrossrefGoogle Scholar

  • Finkelhor, D. (2005). The victimization of children and youth: A comprehensive, national survey. Child Maltreatment, 10, 5 – 25. First citation in articleCrossrefGoogle Scholar

  • Foa, E. B. , Hembree, E. & Rothbaum, B. O. (2007). Prolonged exposure therapy for PTSD: Emotional processing of traumatic experiences. Therapist guide. New York: Oxford University Press. First citation in articleCrossrefGoogle Scholar

  • Foa, E. B. , Keane, T. M. & Friedman, M. J. (2000). Guidelines for treatment of PTSD. Journal of Traumatic Stress, 13, 539 – 588. First citation in articleCrossrefGoogle Scholar

  • Ford, J. D. , Russo, E. M. & Mallon, S. D. (2007). Integrating treatment of posttraumatic stress disorder and substance use disorder. Journal of Counseling & Development, 85, 475 – 489. First citation in articleCrossrefGoogle Scholar

  • Gilbert, R. , Widom, C. S. , Browne, K. , Fergusson, D. , Webb, E. & Janson, S. (2009). Burden and consequences of child maltreatment in high-income countries. The Lancet, 373, 68 – 81. First citation in articleCrossrefGoogle Scholar

  • Harrison, P. A. , Fulkerson, J. A. & Beebe, T. J. (1997). Multiple substance use among adolescent physical and sexual abuse victims. Child Abuse and Neglect, 21, 529 – 539. First citation in articleCrossrefGoogle Scholar

  • Henslee, A. M. & Coffey, S. F. (2010). Exposure therapy for posttraumatic stress disorder in a residential substance use treatment facility. Professional Psychology: Research and Practice, 41, 34 – 40. First citation in articleCrossrefGoogle Scholar

  • Hien, D. A. , Jiang, H. , Campbell, A. N. C. , Hu, M.-C. , Miele, G. M. , Cohen, L. R. et al. (2010). Do treatment improvements in PTSD severity affect substance use outcomes? A secondary analysis from a randomized clinical trial in NIDA’s Clinical Trials Network. The American Journal of Psychiatry, 167, 95 – 101. First citation in articleCrossrefGoogle Scholar

  • Jacobsen, L. K. , Southwick, S. M. & Kosten, T. R. (2001). Substance use disorders in patients with posttraumatic stress disorder: A review of the literature. American Journal of Psychiatry, 158, 1184 – 1190. First citation in articleCrossrefGoogle Scholar

  • Johnson, J. G. , Cohen, P. , Chen, H. , Kasen, S. & Brook, J. S. (2006). Parenting behaviors associated with risk for offspring personality disorder during adulthood. Archives of General Psychiatry, 63, 579 – 587. First citation in articleCrossrefGoogle Scholar

  • Kaysen, D. , Dillworth, T. M. , Simpson, T. , Waldrop, A. , Larimer, M. E. & Resick, P. A. (2007). Domestic violence and alcohol use: Trauma-related symptoms and motives for drinking. Addictive Behaviors, 32, 1272 – 1283. First citation in articleCrossrefGoogle Scholar

  • Khantzian, E. J. (1985). The self-medication hypothesis of addictive disorders: Focus on heroin and cocaine dependence. The American Journal of Psychiatry, 142, 1259 – 1264. First citation in articleCrossrefGoogle Scholar

  • Kilpatrick, D. G. , Aciern, R. , Saunders, B. , Resnick, H. S. , Best, C. L. & Schnurr, P. P. (2000). Risk factors for adolescent substance abuse and dependence data from a national sample. Journal of Consulting and Clinical Psychology, 68, 19 – 30. First citation in articleCrossrefGoogle Scholar

  • Körkel, J. & Schindler, C. (2008). Rückfallprävention mit Alkoholabhängigen: Das strukturierte Trainingsprogramm S. T. A. R. Heidelberg: Springer. First citation in articleGoogle Scholar

  • Lamers-Winkelman, F. , Slot, N. , Bijl, B. & Vijlbrief, A. (2007). Scholieren over mishandeling. Resultaten van een landelijk onderzoek naar de omvang van kindermishandeling onder leerlingen van het voortgezet onderwijs [Missbrauch bei Schülern: Ergebnisse einer Landesweiten Untersuchung über das Ausmaß von Kindesmissbrauch bei Schülern der Sekundarstufe] Duivendrecht: PI Research. First citation in articleGoogle Scholar

  • Leeb, R. T. , Paulozzi, L. , Melanson, C. , Simon, T. & Arias, I. (2008). Child maltreatment surveillance: Uniform definitions for public health and recommended data elements. Atlanta: Centers for Disease Control and Prevention, National Center for Injury Prevention and Control. First citation in articleGoogle Scholar

  • Lipschitz, D. S. , Rasmusson, A. M. , Anyan, W. , Gueorguieva, R. , Billingslea, E. M. , Cromwell, P. F. et al. (2003). Posttraumatic stress disorder and substance use in inner-city adolescent girls. The Journal of Nervous and Mental Disease, 191, 714 – 721. First citation in articleCrossrefGoogle Scholar

  • McMorris, B. J. , Hemphill, S. A. , Toumbourou, J. W. , Catalano, R. F. & Patton, G. C. (2006). Prevalence of substance use and delinquent behavior in adolescents from Victoria, Australia and Washington State, United States. Health Education & Behavior, 34, 634 – 650. First citation in articleCrossrefGoogle Scholar

  • Medrano, M. A. , Zule, W. A. , Hatch, J. & Desmond, D. P. (1999). Prevalence of childhood trauma in a community sample of substance-abusing women. The American Journal of Drug and Alcohol Abuse, 25, 449 – 462. First citation in articleCrossrefGoogle Scholar

  • Mills, K. L. , Teesson, M. , Ross, J. & Peters, L. (2006). Trauma, PTSD, and substance use disorders: Findings from the Australian national survey of mental health and well-being. American Journal of Psychiatry, 163, 652 – 658. First citation in articleCrossrefGoogle Scholar

  • Moberg, C. A. , Weber, S. M. & Curtin, J. J. (2011). Alcohol dose effects on stress response to cued threat vary by threat intensity. Psychopharmacology, 218, 217 – 227. First citation in articleCrossrefGoogle Scholar

  • Najavits, L. M. & Schäfer, I. (2009). Posttraumatische Belastungsstörung und Substanzmissbrauch: Das Therapieprogramm ”Sicherheit finden”. Göttingen: Hogrefe. First citation in articleGoogle Scholar

  • Najavits, L. M. , Harned, M. S. , Gallop, R. J. , Butler, S. F. , Barber, J. P. , Thase, M. E. et al. (2007). Six-month treatment outcomes of cocaine-dependent patients with and without PTSD in a multisite national trial. Journal of Studies on Alcohol and Drugs, 68, 353 – 361. First citation in articleCrossrefGoogle Scholar

  • Najavits, L. M. , Schmitz, M. , Gotthardt, S. & Weiss, R. D. (2005). Seeking Safety plus exposure therapy: An outcome study on dual diagnosis men. Journal of Psychoactive Drugs, 37, 425 – 435. First citation in articleCrossrefGoogle Scholar

  • Norman, S. B. , Tate, S. R. , Anderson, K. G. & Brown, S. A. (2007). Do trauma history and PTSD symptoms influence addiction relapse context? Drug and Alcohol Dependence, 90, 89 – 96. First citation in articleCrossrefGoogle Scholar

  • Ouimette, P. , Coolhart, D. , Funderburk, J. S. , Wade, M. & Brown, P. J. (2007). Precipitants of first substance use in recently abstinent substance use disorder patients with PTSD. Addictive Behaviors, 32, 1719 – 1727. First citation in articleCrossrefGoogle Scholar

  • Ouimette, P. , Moos, R. H. & Finney, J. W. (2003). PTSD treatment and 5-year remission among patients with substance use and posttraumatic stress disorders. Journal of Consulting and Clinical Psychology, 71, 410 – 414. First citation in articleCrossrefGoogle Scholar

  • Ouimette, P. , Read, J. P. , Wade, M. & Tirone, V. (2010). Modeling associations between posttraumatic stress symptoms and substance use. Addictive Behaviors, 35, 64 – 67. First citation in articleCrossrefGoogle Scholar

  • Perkonigg, A. , Kessler, R. C. , Storz, S. & Wittchen, H. U. (2000). Traumatic events and post-traumatic stress disorder in the community: Prevalence, risk factors and comorbidity. Acta Psychiatrica Scandinavica, 101, 46 – 59. First citation in articleCrossrefGoogle Scholar

  • Pirkis, J. E. , Irwin, C. E. , Brindis, C. , Patton, G. C. & Sawyer, M. G. (2003). Adolescent substance use: Beware of international comparisons. The Journal of Adolescent Health, 33, 279 – 286. First citation in articleCrossrefGoogle Scholar

  • Reynolds, M. , Mezey, G. , Chapman, M. , Wheeler, M. , Drummond, C. & Baldacchino, A. (2005). Co-morbid post-traumatic stress disorder in a substance misusing clinical population. Drug and Alcohol Dependence, 77, 251 – 258. First citation in articleCrossrefGoogle Scholar

  • Rothman, E. F. , Edwards, E. M. , Heeren, T. & Hingson, R. W. (2008). Adverse childhood experiences predict earlier age of drinking onset: Results from a representative US sample of current or former drinkers. Pediatrics, 122(2), e298-e304. First citation in articleGoogle Scholar

  • Saladin, M. E. , Brady, K. T. , Dansky, B. S. & Kilpatrick, D. G. (1995). Understanding comorbidity between PTSD and substance use disorders: Two preliminary investigations. Addictive Behaviors, 20, 643 – 655. First citation in articleCrossrefGoogle Scholar

  • Sartor, C. E. , McCutcheon, V. V. , Pommer, N. E. , Nelson, E. C. , Grant, J. D. , Duncan, A. E. et al. (2011). Common genetic and environmental contributions to post-traumatic stress disorder and alcohol dependence in young women. Psychological Medicine, 41, 1497 – 1505. First citation in articleCrossrefGoogle Scholar

  • Saß, H. (2003). Diagnostische Kriterien des Diagnostischen und statistischen Manuals psychischer Störungen DSM-IV-TR. Göttingen: Hogrefe. First citation in articleGoogle Scholar

  • Schäfer, I. & Najavits, L. M. (2007). Clinical challenges in the treatment of patients with posttraumatic stress disorder and substance abuse. Current Opinion in Psychiatry, 20, 614 – 618. First citation in articleCrossrefGoogle Scholar

  • Schäfer, I. , Schulze, C. & Stubenvoll, M. (2011). Psychotherapie bei Abhängigkeitserkrankungen und Posttraumatischer Belastungsstörung. SUCHT, 57, 353 – 361. First citation in articleLinkGoogle Scholar

  • Schauer, M. , Neuner, F. & Elbert, T. (2011). Narrative exposure therapy: A short-term treatment for traumatic stress disorders (2nd ed.). Cambridge, MA: Hogrefe. First citation in articleGoogle Scholar

  • Schnieders, M. , Rassaerts, I. , Schäfer, M. & Soyka, M. (2006). Der Einfluss kindlicher Traumatisierung auf eine spätere Drogenabhängigkeit. Fortschritte der Neurologie und Psychiatrie, 74, 511 – 521. First citation in articleCrossrefGoogle Scholar

  • Schuck, A. M. & Widom, C. S. (2001). Childhood victimization and alcohol symptoms in females: Causal inferences and hypothesized mediators. Child Abuse and Neglect, 25, 1069 – 1092. First citation in articleCrossrefGoogle Scholar

  • Secretary of Health and Human Services. (1993). Alcohol and health. Rockville, MD: U. S. Department of Health and Human Services. First citation in articleGoogle Scholar

  • Simpson, T. L. & Miller, W. R. (2002). Concomitance between childhood sexual and physical abuse and substance use problems. A review. Clinical Psychology Review, 22, 27 – 77. First citation in articleCrossrefGoogle Scholar

  • Simpson, T. L. , Stappenbeck, C. A. , Varra, A. A. , Moore, S. A. & Kaysen, D. (2012). Symptoms of posttraumatic stress predict craving among alcohol treatment seekers: Results of a daily monitoring study. Psychology of Addictive Behaviors. doi: 10.1037/a0027169. First citation in articleGoogle Scholar

  • Singh, V.-A. S. , Thornton, T. & Tonmyr, L. (2011). Determinants of substance abuse in a population of children and adolescents involved with the child welfare system. International Journal of Mental Health and Addiction, 9, 382 – 397. First citation in articleCrossrefGoogle Scholar

  • Stewart, S. , Conrod, P. , Samoluk, S. B. , Pihl, R. & Dongier, M. (2000). Posttraumatic stress disorder symptoms and situation-specific drinking in women substance abusers. Alcoholism Treatment Quarterly, 18(3), 31 – 47. First citation in articleGoogle Scholar

  • Tate, S. R. , Norman, S. B. , McQuaid, J. R. & Brown, S. A. (2007). Health problems of substance-dependent veterans with and those without trauma history. Journal of Substance Abuse Treatment, 33, 25 – 32. First citation in articleCrossrefGoogle Scholar

  • Tonmyr, L. , Thornton, T. , Draca, J. & Wekerle, C. (2010). A review of childhood maltreatment and adolescent substance use relationship. Current Psychiatry Reviews, 6, 223 – 234. First citation in articleCrossrefGoogle Scholar

  • Triffleman, E. (2000). Gender differences in a controlled plot pilot study of psychosocial treatments in substance dependent patients with post-traumatic stress disorder: Design considerations and outcomes. Alcoholism Treatment Quarterly, 18, 113 – 126. First citation in articleCrossrefGoogle Scholar

  • Trull, T. J. , Sher, K. J. , Minks-Brown, C. , Durbin, J. & Burr, R. (2000). Borderline personality disorder and substance use disorders: A review and integration. Clinical Psychology Review, 20, 235 – 253. First citation in articleCrossrefGoogle Scholar

  • U. S. Department of Health and Human Services. (2010). Child Maltreatment 2008. Zugriff am 12. 10. 2011. Verfügbar unter: www.acf.hhs.gov/programs/cb/stats_research/index.htm#can First citation in articleGoogle Scholar

  • Waldrop, A. E. , Back, S. E. , Verduin, M. L. & Brady, K. T. (2007). Triggers for cocaine and alcohol use in the presence and absence of posttraumatic stress disorder. Addictive Behaviors, 32, 634 – 639. First citation in articleCrossrefGoogle Scholar

  • Wekerle, C. , Leung, E. , Goldstein, A. , Thornton, T. & Tonmyr, L. (2009). Substance use among adolescents in child welfare versus adolescents in the general population: A comparison of the Maltreatment and Adolescent Pathways (MAP) longitudinal study and the Ontario Student Drug Use Survey (OSDUS) datasets. London, ON: University of Western Ontario. First citation in articleGoogle Scholar

  • Westermeyer, K. W. P. (2001). Effects of childhood physical abuse on course and severity of substance abuse. American Journal on Addictions, 10, 101 – 110. First citation in articleCrossrefGoogle Scholar

  • White, H. R. & Widom, C. S. (2008). Three potential mediators of the effects of child abuse and neglect on adulthood substance use among women. Journal of Studies on Alcohol and Drugs, 69, 337 – 347. First citation in articleCrossrefGoogle Scholar

  • Widom, C. S. & Maxfield, M. G. (2001). An update on the ”cycle of violence”. Washington, DC: National Institute of Justice. First citation in articleCrossrefGoogle Scholar

  • Wolitzky-Taylor, K. , Bobova, L. , Zinbarg, R. E. , Mineka, S. & Craske, M. G. (2012). Longitudinal investigation of the impact of anxiety and mood disorders in adolescence on subsequent substance use disorder onset and vice versa. Addictive Behaviors, 37, 982 – 985. First citation in articleCrossrefGoogle Scholar

  • Wu, P. , Bird, H. R. , Liu, X. , Duarte, C. S. , Fuller, C. , Fan, B. et al. (2010). Trauma, posttraumatic stress symptoms, and alcohol-use initiation in children. Journal of Studies on Alcohol and Drugs, 71, 326 – 334. First citation in articleCrossrefGoogle Scholar

  • Yeater, E. A. , Austin, J. L. , Green, M. J. & Smith, J. E. (2010). Coping mediates the relationship between posttraumatic stress disorder (PTSD) symptoms and alcohol use in homeless, ethnically diverse women: A preliminary study. Psychological Trauma: Theory, Research, Practice, and Policy, 2, 307 – 310. First citation in articleCrossrefGoogle Scholar

  • Zlotnick, C. (2002). Does subthreshold posttraumatic stress disorder have any clinical relevance? Comprehensive Psychiatry, 43, 413 – 419. First citation in articleCrossrefGoogle Scholar