Arterial stiffness is associated with new-onset chronic kidney disease
Abstract
Summary:Background: A potential independent association between arterial stiffness (AS) and the development of new-onset chronic kidney disease (CKD) has not been thoroughly examined. Patients and methods: A total of 6929 participants were collected from the Kailuan study. All participants were free of CKD at the baseline. The participants were divided into four groups based on their brachial-ankle pulse wave velocity (baPWV) values. Cox regression models were used to analyze the relationship between baPWV values and the risk of new-onset CKD. Results: Over the course of a 10.06-year follow-up period, a total of 962 cases of new-onset CKD were documented. Cox proportional hazards analyses showed that a higher baPWV quartile was linked to an increased risk of new-onset CKD. Conclusions: Brachial-ankle pulse wave velocity has a strong correlation with the development of new-onset CKD. Therefore, baPWV can be considered an innovative indicator for predicting the occurrence of new-onset CKD.
References
1 . The global burden of chronic kidney disease. Lancet. 2020;395(10225):662–4.
2 . Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2020;395(10225):709–33.
3 . Prevalence of chronic kidney disease in China: a cross-sectional survey. Lancet. 2012;379(9818):815–22.
4 . The link between chronic kidney disease and cardiovascular disease. J Nephropathol. 2014;3(3):99–104.
5 . Chronic kidney disease and cardiovascular disease: is there any relationship? Curr Cardiol Rev. 2019;15(1):55–63.
6 Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation. 2003;108(17):2154–69.
7 . Cardiovascular disease in patients with chronic kidney disease: a neglected subgroup. Heart Asia. 2016;8(2):56–61.
8 . Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large managed care organization. Arch Intern Med. 2004;164(6):659–63.
9 . Systematic review: blood pressure target in chronic kidney disease and proteinuria as an effect modifier. Ann Intern Med. 2011;154(8):541–8.
10 . Chronic kidney disease and diabetes. Maturitas. 2012;71(2):94–103.
11 . Role of arterial stiffness in cardiovascular disease. JRSM. Cardiovasc Dis. 2012;1(4).
12 . Arterial Stiffness: A Focus on Vascular Calcification and Its Link to Bone Mineralization. Arterioscler Thromb Vasc Biol. 2020;40(5):1078–93.
13 . Pathophysiology and consequences of arterial stiffness in children with chronic kidney disease. Pediatr Nephrol. 2021;36(7):1683–95.
14 . Arterial stiffness and increased cardiovascular risk in chronic kidney disease. Int Urol Nephrol. 2015;47(7):1157–64.
15 . Chronic Kidney Disease and Arterial Stiffness: A Two-Way Path. Front Med (Lausanne). 2021;8):1157.
16 Brachial-ankle pulse wave velocity is a stronger predictor than blood pressure for atherosclerotic cardiovascular diseases and all-cause mortality: a cohort study. Hypertens Res. 2023;46(9):2100–12.
17 . Chronic Kidney Disease Diagnosis and Management: A Review. Jama. 2019;322(13):1294–304.
18 . Causal Association of Arterial Stiffness With the Risk of Chronic Kidney Disease. JACC: ASIA. 2023.
19 Brachial-ankle pulse wave velocity and systolic time intervals in risk stratification for progression of renal function decline. Am J Hypertens. 2012;25(9):1002–10.
20 Longitudinal Study of Brachial-Ankle Pulse Wave Velocity and Change in Estimated Glomerular Filtration Rate among Chinese Adults. Kidney Blood Press Res. 2021;46(3):266–74.
21 Brachial-ankle pulse wave velocity is independently associated with urine albumin-to-creatinine ratio in a Chinese community-based cohort. Int Urol Nephrol. 2020;52(4):713–20.
22 Temporal trends in prevalence and mortality for chronic kidney disease in China from 1990 to 2019: an analysis of the Global Burden of Disease Study 2019. Clin Kidney J. 2023;16(2):312–21.
23 Obesity and chronic kidney disease: A current review. Obes Sci Pract. 2023;9(2):61–74.
24 . Arterial stiffness in diabetes mellitus. Atherosclerosis. 2015;238(2):370–9.
25 Diabetes mellitus as a risk factor for incident chronic kidney disease and end-stage renal disease in women compared with men: a systematic review and meta-analysis. Endocrine. 2017;55(1):66–76.
26 . Brachial-Ankle Pulse Wave Velocity as a Novel Modality for Detecting Early Diabetic Nephropathy in Type 2 Diabetes Patients. J Diabetes Res. 2021;2021:8862573.
27 Association of Pulse Wave Velocity With Chronic Kidney Disease Progression and Mortality: Findings From the CRIC Study (Chronic Renal Insufficiency Cohort). Hypertension. 2018;71(6):1101–7.
28 Brachial-ankle pulse wave velocity and rate of renal function decline and mortality in chronic kidney disease. Clin J Am Soc Nephrol. 2011;6(4):724–32.
29 Brachial-ankle pulse wave velocity predicts decline in renal function and cardiovascular events in early stages of chronic kidney disease. Int J Med Sci. 2013;10(11):1430–6.
30 Relationship between brachial-ankle and heart-femoral pulse wave velocities and the rapid decline of kidney function. Sci Rep. 2018;8(1):821.
31 . Role of Pulse Wave Velocity in Patients with Chronic Kidney Disease Stages 3–5 on Long-Term Follow-Up. Pulse (Basel). 2014;2(1–4):1–10.
32 . Risk factors associated with brachial-ankle pulse wave velocity among peritoneal dialysis patients in Macao. BMC Nephrol. 2012;13:143.
