Background: Autoantibodies (Abs) against angiotensin-II type 1 (AT1R) and endothelin-1 type A receptors (ETAR) are investigated in the present study as B-cell originated humoral factors that may activate the respective receptors on endothelial cells. The ...
Background: Immunhistopathological and serological data favors an immunopathogenesis of thromboangiitis onliterans(TAO, Buergers disease). Autoantbodies seem to play a major role. Immunoadsorption (IA) proved to be therapeutically effective. We focused ...
Laboratory investigations play an important part in the diagnostic procedures of inflammatory rheumatic diseases. Besides the classical humoral inflammatory parameters (erythrocyte sedimentation rate, C-reactive protein, protein electrophoresis), ...
Abstract. Limbic encephalitis (LE) is an encephalopathic syndrome caused by antineuronal antibodies against extracellular or intracellular neuronal structures. LE may present clinically with a variety of symptoms, ...
Chances and Pitfalls of ANA and ANCA DiagnosticsAbstract. In the context of clinical manifestations, if analysed with high quality laboratory methods and correctly interpreted, ANA and ANCA are an essential tool ...