This review outlines the nature of inter-individual variation in trace element bioavailability, focusing on genetic and epigenetic determinants. We note that pathogenic mutations responsible for dangerously high (or low) status for the micronutrient are ...
Abstract. Folate, a water-soluble vitamin, is a key source of one-carbon groups for DNA methylation, but studies of the DNA methylation response to supplemental folic acid yield inconsistent results. These studies ...
Aim: Several lines of evidence from various scientific approaches indicate that alcohol dependence (AD) in humans is genetically influenced. The aim of this review is to report recent findings, new approaches and developments in revealing the genetic ...
Epigenetic modifications in children associated with maternal emotional stress during pregnancyAbstract. Besides typical physical and hormonal changes during pregnancy, this life period is often associated with an ...
Genetic risk factors and their influence on neural development in autism spectrum disordersAbstract. Abstract. Autism spectrum disorders are etiologically based on genetic and specific gene x biologically ...
Epigenetics–revolutionizing developmental psychopathology?Epigenetics, a discipline concerned with genes in the context of development, has shown that genetic influences on development are always based on an interaction between genome and environment. ...
Abstract. The impact of the environment early in life on long-term outcomes is well known. Stressful experiences during pre- and postnatal development can modulate the genetic programming of specific brain circuits underlying emotional and ...